SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5v8e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_A_ESTA351_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 5v8e BACILLUS CEREUS
PATB1
(Bacillus
cereus) 		5 / 12 GLY A 207
TYR A 196
PRO A 140
TYR A 307
SER A 337
 None
None
None
None
CIT  A 401 (-2.5A)
 1.09A 1fduA-5v8eA:
undetectable		 1fduA-5v8eA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCN_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-D-HIS-L-PRO
-NH2)		 5v8e BACILLUS CEREUS
PATB1
(Bacillus
cereus) 		3 / 3 PHE A 274
TYR A 212
PRO A 344
 None
 1.11A 1mcnA-5v8eA:
undetectable
1mcnB-5v8eA:
undetectable
1mcnP-5v8eA:
undetectable		 1mcnA-5v8eA:
17.45
1mcnB-5v8eA:
17.45
1mcnP-5v8eA:
1.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_C_SUEC1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 5v8e BACILLUS CEREUS
PATB1
(Bacillus
cereus) 		4 / 5 TYR A 165
ILE A 177
LEU A 179
LYS A 178
 None
 1.14A 3sueC-5v8eA:
undetectable		 3sueC-5v8eA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 5v8e BACILLUS CEREUS
PATB1
(Bacillus
cereus) 		3 / 3 TYR A 158
LEU A 170
LYS A 169
 None
 0.72A 3sueD-5v8eA:
undetectable		 3sueD-5v8eA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		 5v8e BACILLUS CEREUS
PATB1
(Bacillus
cereus) 		4 / 8 GLU A 263
TRP A 100
ASN A 204
GLY A 207
 None
 0.99A 4f93B-5v8eA:
undetectable		 4f93B-5v8eA:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_D_ACTD201_0
(RETINOL-BINDING
PROTEIN 2)		 5v8e BACILLUS CEREUS
PATB1
(Bacillus
cereus) 		3 / 3 ASP A 283
HIS A 289
LYS A 282
 None
 0.96A 4qzuD-5v8eA:
undetectable		 4qzuD-5v8eA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5v8e BACILLUS CEREUS
PATB1
(Bacillus
cereus) 		4 / 6 ILE A 295
LEU A 346
HIS A 345
PHE A 137
 None
 0.87A 5vkqA-5v8eA:
undetectable
5vkqB-5v8eA:
undetectable		 5vkqA-5v8eA:
11.09
5vkqB-5v8eA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5v8e BACILLUS CEREUS
PATB1
(Bacillus
cereus) 		4 / 6 PHE A 137
ILE A 295
LEU A 346
HIS A 345
 None
 0.86A 5vkqA-5v8eA:
undetectable
5vkqD-5v8eA:
undetectable		 5vkqA-5v8eA:
11.09
5vkqD-5v8eA:
11.09