SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5v8l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_H_FUAH709_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5v8l PGT145 ANTIBODY,
LIGHT CHAIN
(Homo
sapiens) 		5 / 12 THR N  72
SER N  22
LEU N  11
VAL N  13
ALA N  18
 None
 1.21A 1q23H-5v8lN:
undetectable
1q23I-5v8lN:
undetectable		 1q23H-5v8lN:
21.29
1q23I-5v8lN:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2001_1
(SERUM ALBUMIN)		 5v8l PGT145 ANTIBODY,
LIGHT CHAIN
(Homo
sapiens) 		5 / 11 ARG N  39
VAL N  58
GLY N  57
ALA N  55
LEU N  47
 None
 1.28A 2bxgA-5v8lN:
undetectable		 2bxgA-5v8lN:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5v8l PGT145 ANTIBODY,
LIGHT CHAIN
(Homo
sapiens) 		5 / 11 PHE N  62
ARG N  39
ASP N  82
GLY N  84
THR N 102
 None
 1.12A 3rukD-5v8lN:
undetectable		 3rukD-5v8lN:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_A_AG2A505_1
(HOMOSPERMIDINE
SYNTHASE)		 5v8l PGT145 ANTIBODY,
LIGHT CHAIN
(Homo
sapiens) 		4 / 8 ARG N  61
VAL N  78
ASP N  81
ASP N  82
 None
 0.93A 4xqgA-5v8lN:
undetectable		 4xqgA-5v8lN:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 5v8l PGT145 ANTIBODY,
LIGHT CHAIN
(Homo
sapiens) 		4 / 8 ARG N  61
VAL N  78
ASP N  81
ASP N  82
 None
 0.93A 4xqgB-5v8lN:
undetectable		 4xqgB-5v8lN:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 5v8l PGT145 ANTIBODY,
LIGHT CHAIN
(Homo
sapiens) 		5 / 12 ILE N   4
THR N   5
GLN N   6
THR N 102
VAL N 104
 None
 1.37A 6bzoC-5v8lN:
undetectable		 6bzoC-5v8lN:
11.31