SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5va4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM9_A_FVXA603_1
(TRANSPORTER)		 5va4 TRIM5/CYCLOPHILIN A
V4 FUSION PROTEIN
(Aotus
trivirgatus;
Thermus
thermophilus) 		5 / 11 ASP A 216
VAL A 135
ALA A 136
TYR A 139
PHE A 130
 None
 1.29A 4mm9A-5va4A:
undetectable		 4mm9A-5va4A:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA603_1
(SERUM ALBUMIN)		 5va4 TRIM5/CYCLOPHILIN A
V4 FUSION PROTEIN
(Aotus
trivirgatus;
Thermus
thermophilus) 		5 / 11 LEU A 143
ARG A 221
ASP A 199
LEU A 200
LEU A 211
 None
 1.44A 4or0A-5va4A:
undetectable		 4or0A-5va4A:
13.55