SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vai'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA8_0
(GRAMICIDIN A)		 5vai UNCHARACTERIZED
PROTEIN
(Oryctolagus
cuniculus) 		3 / 3 VAL R 276
TRP R 274
TRP R 243
 None
 1.28A 1c4dA-5vaiR:
undetectable
1c4dB-5vaiR:
undetectable		 1c4dA-5vaiR:
3.15
1c4dB-5vaiR:
3.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J0D_A_ERYA1498_0
(CYTOCHROME P450 3A4)		 5vai UNCHARACTERIZED
PROTEIN
(Oryctolagus
cuniculus) 		5 / 12 PHE R 184
ILE R 317
ILE R 313
ALA R 238
GLU R 247
 None
 1.12A 2j0dA-5vaiR:
undetectable		 2j0dA-5vaiR:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA801_1
(PROSTAGLANDIN
REDUCTASE 1)		 5vai UNCHARACTERIZED
PROTEIN
(Oryctolagus
cuniculus) 		4 / 8 VAL R 237
TYR R 241
TYR R 145
VAL R 194
 None
 1.21A 2y05A-5vaiR:
undetectable
2y05B-5vaiR:
undetectable		 2y05A-5vaiR:
22.32
2y05B-5vaiR:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5vai UNCHARACTERIZED
PROTEIN
(Oryctolagus
cuniculus) 		4 / 6 GLN R 410
PHE R 413
PHE R 169
LEU R 172
 None
 1.09A 3ablP-5vaiR:
undetectable
3ablW-5vaiR:
undetectable		 3ablP-5vaiR:
19.18
3ablW-5vaiR:
10.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 5vai UNCHARACTERIZED
PROTEIN
(Oryctolagus
cuniculus) 		5 / 12 GLU R 364
ASN R 320
GLY R 361
ASN R 240
PHE R 187
 None
 1.25A 3k13A-5vaiR:
undetectable		 3k13A-5vaiR:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_2
(ADENOSINE KINASE,
PUTATIVE)		 5vai UNCHARACTERIZED
PROTEIN
(Oryctolagus
cuniculus) 		4 / 5 LEU R 359
ALA R 399
PHE R 184
ASN R 406
 None
 1.16A 3uq6A-5vaiR:
undetectable		 3uq6A-5vaiR:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_B_MXMB606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5vai UNCHARACTERIZED
PROTEIN
(Oryctolagus
cuniculus) 		5 / 12 ILE R 188
LEU R 192
ALA R 153
SER R 155
LEU R 159
 None
 1.02A 4m11B-5vaiR:
undetectable		 4m11B-5vaiR:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5vai UNCHARACTERIZED
PROTEIN
(Oryctolagus
cuniculus) 		4 / 8 ASN R 240
GLU R 247
TYR R 242
TYR R 252
 None
 1.16A 4mj8A-5vaiR:
undetectable
4mj8C-5vaiR:
undetectable		 4mj8A-5vaiR:
15.07
4mj8C-5vaiR:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVP_B_GBMB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 5vai UNCHARACTERIZED
PROTEIN
(Oryctolagus
cuniculus) 		5 / 12 LEU R 356
VAL R 327
ILE R 323
LEU R 183
LEU R 244
 None
 1.31A 4yvpB-5vaiR:
undetectable		 4yvpB-5vaiR:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5vai UNCHARACTERIZED
PROTEIN
(Oryctolagus
cuniculus) 		4 / 6 GLN R 410
PHE R 413
PHE R 169
LEU R 172
 None
 1.12A 5b1bC-5vaiR:
2.0
5b1bJ-5vaiR:
undetectable		 5b1bC-5vaiR:
19.18
5b1bJ-5vaiR:
10.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5vai UNCHARACTERIZED
PROTEIN
(Oryctolagus
cuniculus) 		4 / 6 GLN R 410
PHE R 413
PHE R 169
LEU R 172
 None
 1.01A 5z84P-5vaiR:
2.1
5z84W-5vaiR:
undetectable		 5z84P-5vaiR:
19.18
5z84W-5vaiR:
10.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5vai UNCHARACTERIZED
PROTEIN
(Oryctolagus
cuniculus) 		4 / 6 GLN R 410
PHE R 413
PHE R 169
LEU R 172
 None
 1.04A 5z85P-5vaiR:
2.6
5z85W-5vaiR:
undetectable		 5z85P-5vaiR:
19.18
5z85W-5vaiR:
10.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5vai UNCHARACTERIZED
PROTEIN
(Oryctolagus
cuniculus) 		4 / 6 GLN R 410
PHE R 413
PHE R 169
LEU R 172
 None
 1.01A 5z86C-5vaiR:
2.7
5z86J-5vaiR:
undetectable		 5z86C-5vaiR:
19.18
5z86J-5vaiR:
10.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5vai UNCHARACTERIZED
PROTEIN
(Oryctolagus
cuniculus) 		4 / 6 GLN R 410
PHE R 413
PHE R 169
LEU R 172
 None
 1.04A 5z86P-5vaiR:
2.6
5z86W-5vaiR:
undetectable		 5z86P-5vaiR:
19.18
5z86W-5vaiR:
10.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5vai UNCHARACTERIZED
PROTEIN
(Oryctolagus
cuniculus) 		4 / 6 GLN R 410
PHE R 413
PHE R 169
LEU R 172
 None
 1.06A 5zcoP-5vaiR:
3.6
5zcoW-5vaiR:
undetectable		 5zcoP-5vaiR:
19.18
5zcoW-5vaiR:
10.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5vai UNCHARACTERIZED
PROTEIN
(Oryctolagus
cuniculus) 		4 / 6 GLN R 410
PHE R 413
PHE R 169
LEU R 172
 None
 1.00A 5zcpC-5vaiR:
2.6
5zcpJ-5vaiR:
undetectable		 5zcpC-5vaiR:
19.18
5zcpJ-5vaiR:
10.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5vai UNCHARACTERIZED
PROTEIN
(Oryctolagus
cuniculus) 		4 / 6 GLN R 410
PHE R 413
PHE R 169
LEU R 172
 None
 1.02A 5zcpP-5vaiR:
2.1
5zcpW-5vaiR:
undetectable		 5zcpP-5vaiR:
19.18
5zcpW-5vaiR:
10.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H3D_A_DHIA601_0
(DUF2338
DOMAIN-CONTAINING
PROTEIN)		 5vai UNCHARACTERIZED
PROTEIN
(Oryctolagus
cuniculus) 		4 / 5 TYR R 250
ASN R 177
TYR R 178
PHE R 266
 None
 1.15A 6h3dA-5vaiR:
2.3		 6h3dA-5vaiR:
19.80