SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vc1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1C4D_D_DVAD8_0 (GRAMICIDIN A)	5vc1	L-SELECTIN (Homo sapiens)	3 / 3	TRP A 50 VAL A 27 TRP A 12	None	1.24A	1c4dC-5vc1A: undetectable 1c4dD-5vc1A: undetectable	1c4dC-5vc1A: 5.26 1c4dD-5vc1A: 5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NK7_B_SAMB770_0 (23S RRNA METHYLTRANSFERASE)	5vc1	L-SELECTIN (Homo sapiens)	5 / 12	GLY A 58 GLY A 57 ILE A 53 SER A 68 LEU A 69	None None None None PEG A 207 (-4.4A)	0.99A	3nk7B-5vc1A: undetectable	3nk7B-5vc1A: 17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V81_C_NVPC901_1 (HIV-1 REVERSE TRANSCRIPTASE P66 SUBUNIT)	5vc1	L-SELECTIN (Homo sapiens)	4 / 8	VAL A 27 TYR A 49 TYR A 5 TYR A 37	None	1.10A	3v81C-5vc1A: undetectable	3v81C-5vc1A: 14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZQ8_D_DVAD8_0 (VAL-GRAMICIDIN A)	5vc1	L-SELECTIN (Homo sapiens)	3 / 3	TRP A 50 VAL A 27 TRP A 12	None	0.99A	3zq8C-5vc1A: undetectable 3zq8D-5vc1A: undetectable	3zq8C-5vc1A: 5.26 3zq8D-5vc1A: 5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PWD_C_NVPC901_1 (HIV-1 REVERSE TRANSCRIPTASE, P66 SUBUNIT)	5vc1	L-SELECTIN (Homo sapiens)	4 / 8	VAL A 27 TYR A 49 TYR A 5 TYR A 37	None	1.11A	4pwdC-5vc1A: undetectable	4pwdC-5vc1A: 14.63

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1C4D_D_DVAD8_0","GRAMICIDIN A","5vc1","L-SELECTIN","Homo sapiens",3,"TRP A  50;VAL A  27;TRP A  12","None","1.24A","1c4dC-5vc1A:undetectable;1c4dD-5vc1A:undetectable","1c4dC-5vc1A:5.26;1c4dD-5vc1A:5.26"],["3NK7_B_SAMB770_0","23S RRNA METHYLTRANSFERASE","5vc1","L-SELECTIN","Homo sapiens",5,"GLY A  58;GLY A  57;ILE A  53;SER A  68;LEU A  69","None;None;None;None;PEG A 207 (-4.4A)","0.99A","3nk7B-5vc1A:undetectable","3nk7B-5vc1A:17.44"],["3V81_C_NVPC901_1","HIV-1 REVERSE TRANSCRIPTASE P66 SUBUNIT","5vc1","L-SELECTIN","Homo sapiens",4,"VAL A  27;TYR A  49;TYR A   5;TYR A  37","None","1.10A","3v81C-5vc1A:undetectable","3v81C-5vc1A:14.63"],["3ZQ8_D_DVAD8_0","VAL-GRAMICIDIN A","5vc1","L-SELECTIN","Homo sapiens",3,"TRP A  50;VAL A  27;TRP A  12","None","0.99A","3zq8C-5vc1A:undetectable;3zq8D-5vc1A:undetectable","3zq8C-5vc1A:5.26;3zq8D-5vc1A:5.26"],["4PWD_C_NVPC901_1","HIV-1 REVERSE TRANSCRIPTASE, P66 SUBUNIT","5vc1","L-SELECTIN","Homo sapiens",4,"VAL A  27;TYR A  49;TYR A   5;TYR A  37","None","1.11A","4pwdC-5vc1A:undetectable","4pwdC-5vc1A:14.63"]]