SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vc2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1CQP_B_803B311_1 (ANTIGEN CD11A (P180))	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	4 / 7	VAL A 206 LEU A 237 VAL A 220 LEU A 228	None	0.74A	1cqpA-5vc2A: 2.7 1cqpB-5vc2A: 2.6	1cqpA-5vc2A: 18.10 1cqpB-5vc2A: 18.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_A_FFOA1002_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	5 / 12	ALA A 173 ASN A 342 SER A 350 PHE A 352 ARG A 358	None	0.88A	1dfoA-5vc2A: 53.2	1dfoA-5vc2A: 52.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_A_FFOA1002_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	5 / 12	SER A 172 ALA A 173 ASN A 342 PHE A 352 ARG A 358	None	0.85A	1dfoA-5vc2A: 53.2	1dfoA-5vc2A: 52.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_B_FFOB2002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	5 / 12	ALA A 173 ASN A 342 SER A 350 PHE A 352 ARG A 358	None	0.89A	1dfoB-5vc2A: 53.1	1dfoB-5vc2A: 52.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_B_FFOB2002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	5 / 12	SER A 172 ALA A 173 ASN A 342 PHE A 352 ARG A 358	None	0.85A	1dfoB-5vc2A: 53.1	1dfoB-5vc2A: 52.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_C_FFOC3002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	5 / 12	ALA A 173 ASN A 342 SER A 350 PHE A 352 ARG A 358	None	0.88A	1dfoC-5vc2A: 53.1	1dfoC-5vc2A: 52.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_C_FFOC3002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	5 / 12	SER A 172 ALA A 173 ASN A 342 PHE A 352 ARG A 358	None	0.86A	1dfoC-5vc2A: 53.1	1dfoC-5vc2A: 52.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_D_FFOD4002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	5 / 12	ALA A 173 ASN A 342 SER A 350 PHE A 352 ARG A 358	None	0.89A	1dfoD-5vc2A: 53.2	1dfoD-5vc2A: 52.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DFO_D_FFOD4002_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	5 / 12	SER A 172 ALA A 173 ASN A 342 PHE A 352 ARG A 358	None	0.86A	1dfoD-5vc2A: 53.2	1dfoD-5vc2A: 52.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DYR_A_TOPA407_1 (DIHYDROFOLATE REDUCTASE)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	5 / 11	ILE A 359 ALA A 31 ILE A 344 PRO A 345 ILE A 357	None	1.07A	1dyrA-5vc2A: 2.2	1dyrA-5vc2A: 20.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_A_FFOA1293_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	5 / 12	ALA A 173 ASN A 342 SER A 350 PHE A 352 ARG A 358	None	0.90A	1eqbA-5vc2A: 53.1	1eqbA-5vc2A: 51.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_A_FFOA1293_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	5 / 12	SER A 172 ALA A 173 ASN A 342 PHE A 352 ARG A 358	None	0.90A	1eqbA-5vc2A: 53.1	1eqbA-5vc2A: 51.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_A_GLYA1292_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	4 / 8	SER A 32 SER A 172 LYS A 226 ARG A 358	None	0.71A	1eqbA-5vc2A: 53.1 1eqbB-5vc2A: 51.7	1eqbA-5vc2A: 51.88 1eqbB-5vc2A: 51.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_B_FFOB2293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	5 / 12	ALA A 173 ASN A 342 SER A 350 PHE A 352 ARG A 358	None	0.90A	1eqbB-5vc2A: 51.7	1eqbB-5vc2A: 51.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_B_GLYB2292_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	4 / 8	SER A 32 SER A 172 LYS A 226 ARG A 358	None	0.72A	1eqbA-5vc2A: 53.1 1eqbB-5vc2A: 51.7	1eqbA-5vc2A: 51.88 1eqbB-5vc2A: 51.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_C_FFOC3293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	5 / 12	ALA A 173 ASN A 342 SER A 350 PHE A 352 ARG A 358	None	0.90A	1eqbC-5vc2A: 52.9	1eqbC-5vc2A: 51.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_C_FFOC3293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	5 / 12	SER A 172 ALA A 173 ASN A 342 PHE A 352 ARG A 358	None	0.90A	1eqbC-5vc2A: 52.9	1eqbC-5vc2A: 51.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_C_GLYC3292_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	4 / 8	SER A 32 SER A 172 LYS A 226 ARG A 358	None	0.72A	1eqbC-5vc2A: 52.9 1eqbD-5vc2A: 53.0	1eqbC-5vc2A: 51.88 1eqbD-5vc2A: 51.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_D_FFOD4293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	5 / 12	ALA A 173 ASN A 342 SER A 350 PHE A 352 ARG A 358	None	0.90A	1eqbD-5vc2A: 53.0	1eqbD-5vc2A: 51.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_D_FFOD4293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	5 / 12	SER A 172 ALA A 173 ASN A 342 PHE A 352 ARG A 358	None	0.90A	1eqbD-5vc2A: 53.0	1eqbD-5vc2A: 51.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1EQB_D_GLYD4292_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	4 / 8	SER A 32 SER A 172 LYS A 226 ARG A 358	None	0.71A	1eqbC-5vc2A: 52.9 1eqbD-5vc2A: 53.0	1eqbC-5vc2A: 51.88 1eqbD-5vc2A: 51.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SDT_B_MK1B902_1 (PROTEASE RETROPEPSIN)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	6 / 10	LEU A 195 ASP A 197 GLY A 233 GLY A 234 ILE A 235 VAL A 102	None	1.27A	1sdtA-5vc2A: undetectable	1sdtA-5vc2A: 14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BFP_D_H4BD1290_1 (PTERIDINE REDUCTASE 1)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	4 / 8	PHE A 318 TYR A 323 LEU A 297 LEU A 304	None	0.75A	2bfpD-5vc2A: undetectable	2bfpD-5vc2A: 21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CD2_A_FOLA307_0 (DIHYDROFOLATE REDUCTASE)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	5 / 12	ALA A 296 LEU A 293 ILE A 381 LEU A 401 ILE A 376	None	0.97A	2cd2A-5vc2A: undetectable	2cd2A-5vc2A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HW2_A_RFPA1200_1 (RIFAMPIN ADP-RIBOSYL TRANSFERASE)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	5 / 12	ALA A 335 GLY A 333 MET A 29 GLY A 360 LEU A 314	None	1.07A	2hw2A-5vc2A: undetectable	2hw2A-5vc2A: 14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2O4P_A_TPVA300_1 (PROTEASE)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	5 / 11	LEU A 195 ASP A 197 GLY A 234 ILE A 235 VAL A 102	None	1.10A	2o4pA-5vc2A: undetectable	2o4pA-5vc2A: 13.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2VMY_B_GLYB502_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	4 / 8	SER A 32 SER A 172 LYS A 226 ARG A 358	None	0.75A	2vmyA-5vc2A: 51.4 2vmyB-5vc2A: 48.8	2vmyA-5vc2A: 54.01 2vmyB-5vc2A: 54.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WEK_B_DIFB1374_1 (ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	4 / 6	PRO A 231 ILE A 235 ASN A 274 LEU A 82	None	1.30A	2wekB-5vc2A: undetectable	2wekB-5vc2A: 22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7K_A_SALA1302_1 (LYSR-TYPE REGULATORY PROTEIN)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	5 / 11	ILE A 198 GLY A 196 GLY A 170 HIS A 210 ILE A 178	None	1.12A	2y7kA-5vc2A: undetectable	2y7kA-5vc2A: 18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A25_A_SAMA279_0 (UNCHARACTERIZED PROTEIN PH0793)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	5 / 12	SER A 221 ASN A 99 ILE A 30 THR A 227 ASN A 340	None	1.06A	3a25A-5vc2A: undetectable	3a25A-5vc2A: 22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A2Q_A_ACAA602_1 (6-AMINOHEXANOATE-CYC LIC-DIMER HYDROLASE)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	4 / 7	ASN A 89 ALA A 75 ALA A 79 GLN A 91	None	0.59A	3a2qA-5vc2A: undetectable	3a2qA-5vc2A: 22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D1Y_A_ROCA201_2 (HIV-1 PROTEASE)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	5 / 9	LEU A 195 ASP A 197 GLY A 234 ILE A 235 VAL A 102	None	1.17A	3d1yB-5vc2A: undetectable	3d1yB-5vc2A: 13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OWX_A_XRAA233_2 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	4 / 5	VAL A 144 PHE A 183 ILE A 178 PHE A 180	None	0.91A	3owxB-5vc2A: undetectable	3owxB-5vc2A: 20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OZV_B_ECNB411_1 (FLAVOHEMOGLOBIN)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	5 / 9	ILE A 359 ILE A 357 ALA A 331 LEU A 332 LEU A 297	None	0.89A	3ozvB-5vc2A: undetectable	3ozvB-5vc2A: 21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RFM_A_CFFA330_1 (ADENOSINE RECEPTOR A2A)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	4 / 7	VAL A 144 PHE A 171 LEU A 315 ASN A 342	None	0.97A	3rfmA-5vc2A: undetectable	3rfmA-5vc2A: 20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VW1_D_CVID301_1 (PUTATIVE REGULATORY PROTEIN)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	3 / 3	TYR A 411 MET A 404 LEU A 364	None	0.92A	3vw1D-5vc2A: undetectable	3vw1D-5vc2A: 18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5N_A_PXLA300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	4 / 7	GLY A 170 GLY A 196 VAL A 201 CYH A 217	None	0.89A	4c5nA-5vc2A: 5.1	4c5nA-5vc2A: 18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IJI_F_BEZF501_0 (GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN YIBF)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	4 / 8	ASN A 289 SER A 361 LEU A 285 ARG A 229	None	1.18A	4ijiF-5vc2A: undetectable	4ijiF-5vc2A: 20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KRH_B_SAMB900_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE 2)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	5 / 12	PHE A 83 GLY A 234 GLY A 95 SER A 221 ARG A 232	None	0.89A	4krhB-5vc2A: 3.2	4krhB-5vc2A: 21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Q15_A_HFGA803_1 (PROLINE--TRNA LIGASE)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	3 / 3	GLU A 19 THR A 338 HIS A 26	None	0.77A	4q15A-5vc2A: undetectable	4q15A-5vc2A: 21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Q15_B_HFGB803_1 (PROLINE--TRNA LIGASE)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	3 / 3	GLU A 19 THR A 338 HIS A 26	None	0.78A	4q15B-5vc2A: undetectable	4q15B-5vc2A: 21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TXN_A_URFA302_1 (URIDINE PHOSPHORYLASE)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	4 / 7	GLY A 333 MET A 29 ALA A 331 ILE A 384	None	0.83A	4txnA-5vc2A: undetectable	4txnA-5vc2A: 22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TXN_B_URFB302_1 (URIDINE PHOSPHORYLASE)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	4 / 7	GLY A 333 MET A 29 ALA A 331 ILE A 384	None	0.84A	4txnB-5vc2A: undetectable	4txnB-5vc2A: 22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TXN_C_URFC302_1 (URIDINE PHOSPHORYLASE)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	4 / 7	GLY A 333 MET A 29 ALA A 331 ILE A 384	None	0.81A	4txnC-5vc2A: undetectable	4txnC-5vc2A: 22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TXN_D_URFD302_1 (URIDINE PHOSPHORYLASE)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	4 / 7	GLY A 333 MET A 29 ALA A 331 ILE A 384	None	0.83A	4txnD-5vc2A: undetectable	4txnD-5vc2A: 22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	4 / 4	ASN A 99 LEU A 194 PHE A 171 TYR A 142	None	1.41A	4u14A-5vc2A: undetectable	4u14A-5vc2A: 21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Y8W_C_STRC603_1 (CYTOCHROME P450 21-HYDROXYLASE)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	5 / 12	LEU A 297 VAL A 339 ILE A 337 ILE A 357 GLY A 356	None	0.94A	4y8wC-5vc2A: undetectable	4y8wC-5vc2A: 22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YDQ_B_HFGB802_1 (PROLINE--TRNA LIGASE)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	3 / 3	GLU A 19 THR A 338 HIS A 26	None	0.83A	4ydqB-5vc2A: undetectable	4ydqB-5vc2A: 19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IMS_B_ACTB713_0 (ACETOLACTATE SYNTHASE CATALYTIC SUBUNIT, MITOCHONDRIAL)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	3 / 3	GLY A 308 GLN A 291 LYS A 298	None	0.89A	5imsB-5vc2A: undetectable	5imsB-5vc2A: 22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NUN_A_Z80A201_1 (BETA-LACTOGLOBULIN)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	5 / 9	ALA A 88 ILE A 198 ASN A 84 PHE A 83 ALA A 79	None	0.89A	5nunA-5vc2A: undetectable	5nunA-5vc2A: 12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YCN_A_8LXA501_0 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	5vc2	SERINE HYDROXYMETHYLTRANSFE RASE (Helicobacter pylori)	6 / 12	GLY A 378 TYR A 323 VAL A 339 ILE A 337 MET A 29 MET A 316	None	1.45A	5ycnA-5vc2A: undetectable	5ycnA-5vc2A: 21.66

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1CQP_B_803B311_1","ANTIGEN CD11A (P180);ANTIGEN CD11A (P180)","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",4,"VAL A 206;LEU A 237;VAL A 220;LEU A 228","None","0.74A","1cqpA-5vc2A:2.7;1cqpB-5vc2A:2.6","1cqpA-5vc2A:18.10;1cqpB-5vc2A:18.10"],["1DFO_A_FFOA1002_0","SERINE HYDROXYMETHYLTRANSFERASE","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",5,"ALA A 173;ASN A 342;SER A 350;PHE A 352;ARG A 358","None","0.88A","1dfoA-5vc2A:53.2","1dfoA-5vc2A:52.11"],["1DFO_A_FFOA1002_0","SERINE HYDROXYMETHYLTRANSFERASE","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",5,"SER A 172;ALA A 173;ASN A 342;PHE A 352;ARG A 358","None","0.85A","1dfoA-5vc2A:53.2","1dfoA-5vc2A:52.11"],["1DFO_B_FFOB2002_1","SERINE HYDROXYMETHYLTRANSFERASE","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",5,"ALA A 173;ASN A 342;SER A 350;PHE A 352;ARG A 358","None","0.89A","1dfoB-5vc2A:53.1","1dfoB-5vc2A:52.11"],["1DFO_B_FFOB2002_1","SERINE HYDROXYMETHYLTRANSFERASE","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",5,"SER A 172;ALA A 173;ASN A 342;PHE A 352;ARG A 358","None","0.85A","1dfoB-5vc2A:53.1","1dfoB-5vc2A:52.11"],["1DFO_C_FFOC3002_1","SERINE HYDROXYMETHYLTRANSFERASE","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",5,"ALA A 173;ASN A 342;SER A 350;PHE A 352;ARG A 358","None","0.88A","1dfoC-5vc2A:53.1","1dfoC-5vc2A:52.11"],["1DFO_C_FFOC3002_1","SERINE HYDROXYMETHYLTRANSFERASE","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",5,"SER A 172;ALA A 173;ASN A 342;PHE A 352;ARG A 358","None","0.86A","1dfoC-5vc2A:53.1","1dfoC-5vc2A:52.11"],["1DFO_D_FFOD4002_1","SERINE HYDROXYMETHYLTRANSFERASE","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",5,"ALA A 173;ASN A 342;SER A 350;PHE A 352;ARG A 358","None","0.89A","1dfoD-5vc2A:53.2","1dfoD-5vc2A:52.11"],["1DFO_D_FFOD4002_1","SERINE HYDROXYMETHYLTRANSFERASE","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",5,"SER A 172;ALA A 173;ASN A 342;PHE A 352;ARG A 358","None","0.86A","1dfoD-5vc2A:53.2","1dfoD-5vc2A:52.11"],["1DYR_A_TOPA407_1","DIHYDROFOLATE REDUCTASE","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",5,"ILE A 359;ALA A  31;ILE A 344;PRO A 345;ILE A 357","None","1.07A","1dyrA-5vc2A:2.2","1dyrA-5vc2A:20.00"],["1EQB_A_FFOA1293_0","SERINE HYDROXYMETHYLTRANSFERASE","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",5,"ALA A 173;ASN A 342;SER A 350;PHE A 352;ARG A 358","None","0.90A","1eqbA-5vc2A:53.1","1eqbA-5vc2A:51.88"],["1EQB_A_FFOA1293_0","SERINE HYDROXYMETHYLTRANSFERASE","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",5,"SER A 172;ALA A 173;ASN A 342;PHE A 352;ARG A 358","None","0.90A","1eqbA-5vc2A:53.1","1eqbA-5vc2A:51.88"],["1EQB_A_GLYA1292_0","SERINE HYDROXYMETHYLTRANSFERASE","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",4,"SER A  32;SER A 172;LYS A 226;ARG A 358","None","0.71A","1eqbA-5vc2A:53.1;1eqbB-5vc2A:51.7","1eqbA-5vc2A:51.88;1eqbB-5vc2A:51.88"],["1EQB_B_FFOB2293_1","SERINE HYDROXYMETHYLTRANSFERASE","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",5,"ALA A 173;ASN A 342;SER A 350;PHE A 352;ARG A 358","None","0.90A","1eqbB-5vc2A:51.7","1eqbB-5vc2A:51.88"],["1EQB_B_GLYB2292_0","SERINE HYDROXYMETHYLTRANSFERASE","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",4,"SER A  32;SER A 172;LYS A 226;ARG A 358","None","0.72A","1eqbA-5vc2A:53.1;1eqbB-5vc2A:51.7","1eqbA-5vc2A:51.88;1eqbB-5vc2A:51.88"],["1EQB_C_FFOC3293_1","SERINE HYDROXYMETHYLTRANSFERASE","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",5,"ALA A 173;ASN A 342;SER A 350;PHE A 352;ARG A 358","None","0.90A","1eqbC-5vc2A:52.9","1eqbC-5vc2A:51.88"],["1EQB_C_FFOC3293_1","SERINE HYDROXYMETHYLTRANSFERASE","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",5,"SER A 172;ALA A 173;ASN A 342;PHE A 352;ARG A 358","None","0.90A","1eqbC-5vc2A:52.9","1eqbC-5vc2A:51.88"],["1EQB_C_GLYC3292_0","SERINE HYDROXYMETHYLTRANSFERASE","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",4,"SER A  32;SER A 172;LYS A 226;ARG A 358","None","0.72A","1eqbC-5vc2A:52.9;1eqbD-5vc2A:53.0","1eqbC-5vc2A:51.88;1eqbD-5vc2A:51.88"],["1EQB_D_FFOD4293_1","SERINE HYDROXYMETHYLTRANSFERASE","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",5,"ALA A 173;ASN A 342;SER A 350;PHE A 352;ARG A 358","None","0.90A","1eqbD-5vc2A:53.0","1eqbD-5vc2A:51.88"],["1EQB_D_FFOD4293_1","SERINE HYDROXYMETHYLTRANSFERASE","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",5,"SER A 172;ALA A 173;ASN A 342;PHE A 352;ARG A 358","None","0.90A","1eqbD-5vc2A:53.0","1eqbD-5vc2A:51.88"],["1EQB_D_GLYD4292_0","SERINE HYDROXYMETHYLTRANSFERASE","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",4,"SER A  32;SER A 172;LYS A 226;ARG A 358","None","0.71A","1eqbC-5vc2A:52.9;1eqbD-5vc2A:53.0","1eqbC-5vc2A:51.88;1eqbD-5vc2A:51.88"],["1SDT_B_MK1B902_1","PROTEASE RETROPEPSIN;PROTEASE RETROPEPSIN","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",6,"LEU A 195;ASP A 197;GLY A 233;GLY A 234;ILE A 235;VAL A 102","None","1.27A","1sdtA-5vc2A:undetectable","1sdtA-5vc2A:14.15"],["2BFP_D_H4BD1290_1","PTERIDINE REDUCTASE 1","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",4,"PHE A 318;TYR A 323;LEU A 297;LEU A 304","None","0.75A","2bfpD-5vc2A:undetectable","2bfpD-5vc2A:21.35"],["2CD2_A_FOLA307_0","DIHYDROFOLATE REDUCTASE","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",5,"ALA A 296;LEU A 293;ILE A 381;LEU A 401;ILE A 376","None","0.97A","2cd2A-5vc2A:undetectable","2cd2A-5vc2A:20.00"],["2HW2_A_RFPA1200_1","RIFAMPIN ADP-RIBOSYL TRANSFERASE","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",5,"ALA A 335;GLY A 333;MET A  29;GLY A 360;LEU A 314","None","1.07A","2hw2A-5vc2A:undetectable","2hw2A-5vc2A:14.76"],["2O4P_A_TPVA300_1","PROTEASE","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",5,"LEU A 195;ASP A 197;GLY A 234;ILE A 235;VAL A 102","None","1.10A","2o4pA-5vc2A:undetectable","2o4pA-5vc2A:13.44"],["2VMY_B_GLYB502_0","SERINE HYDROXYMETHYLTRANSFERASE","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",4,"SER A  32;SER A 172;LYS A 226;ARG A 358","None","0.75A","2vmyA-5vc2A:51.4;2vmyB-5vc2A:48.8","2vmyA-5vc2A:54.01;2vmyB-5vc2A:54.01"],["2WEK_B_DIFB1374_1","ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",4,"PRO A 231;ILE A 235;ASN A 274;LEU A  82","None","1.30A","2wekB-5vc2A:undetectable","2wekB-5vc2A:22.97"],["2Y7K_A_SALA1302_1","LYSR-TYPE REGULATORY PROTEIN","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",5,"ILE A 198;GLY A 196;GLY A 170;HIS A 210;ILE A 178","None","1.12A","2y7kA-5vc2A:undetectable","2y7kA-5vc2A:18.50"],["3A25_A_SAMA279_0","UNCHARACTERIZED PROTEIN PH0793","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",5,"SER A 221;ASN A  99;ILE A  30;THR A 227;ASN A 340","None","1.06A","3a25A-5vc2A:undetectable","3a25A-5vc2A:22.85"],["3A2Q_A_ACAA602_1","6-AMINOHEXANOATE-CYCLIC-DIMER HYDROLASE","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",4,"ASN A  89;ALA A  75;ALA A  79;GLN A  91","None","0.59A","3a2qA-5vc2A:undetectable","3a2qA-5vc2A:22.14"],["3D1Y_A_ROCA201_2","HIV-1 PROTEASE;HIV-1 PROTEASE","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",5,"LEU A 195;ASP A 197;GLY A 234;ILE A 235;VAL A 102","None","1.17A","3d1yB-5vc2A:undetectable","3d1yB-5vc2A:13.92"],["3OWX_A_XRAA233_2","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE];RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",4,"VAL A 144;PHE A 183;ILE A 178;PHE A 180","None","0.91A","3owxB-5vc2A:undetectable","3owxB-5vc2A:20.47"],["3OZV_B_ECNB411_1","FLAVOHEMOGLOBIN","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",5,"ILE A 359;ILE A 357;ALA A 331;LEU A 332;LEU A 297","None","0.89A","3ozvB-5vc2A:undetectable","3ozvB-5vc2A:21.89"],["3RFM_A_CFFA330_1","ADENOSINE RECEPTOR A2A","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",4,"VAL A 144;PHE A 171;LEU A 315;ASN A 342","None","0.97A","3rfmA-5vc2A:undetectable","3rfmA-5vc2A:20.92"],["3VW1_D_CVID301_1","PUTATIVE REGULATORY PROTEIN","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",3,"TYR A 411;MET A 404;LEU A 364","None","0.92A","3vw1D-5vc2A:undetectable","3vw1D-5vc2A:18.31"],["4C5N_A_PXLA300_1","PHOSPHOMETHYLPYRIMIDINE KINASE","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",4,"GLY A 170;GLY A 196;VAL A 201;CYH A 217","None","0.89A","4c5nA-5vc2A:5.1","4c5nA-5vc2A:18.89"],["4IJI_F_BEZF501_0","GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN YIBF","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",4,"ASN A 289;SER A 361;LEU A 285;ARG A 229","None","1.18A","4ijiF-5vc2A:undetectable","4ijiF-5vc2A:20.19"],["4KRH_B_SAMB900_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE 2","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",5,"PHE A  83;GLY A 234;GLY A  95;SER A 221;ARG A 232","None","0.89A","4krhB-5vc2A:3.2","4krhB-5vc2A:21.40"],["4Q15_A_HFGA803_1","PROLINE--TRNA LIGASE","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",3,"GLU A  19;THR A 338;HIS A  26","None","0.77A","4q15A-5vc2A:undetectable","4q15A-5vc2A:21.13"],["4Q15_B_HFGB803_1","PROLINE--TRNA LIGASE","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",3,"GLU A  19;THR A 338;HIS A  26","None","0.78A","4q15B-5vc2A:undetectable","4q15B-5vc2A:21.13"],["4TXN_A_URFA302_1","URIDINE PHOSPHORYLASE","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",4,"GLY A 333;MET A  29;ALA A 331;ILE A 384","None","0.83A","4txnA-5vc2A:undetectable","4txnA-5vc2A:22.76"],["4TXN_B_URFB302_1","URIDINE PHOSPHORYLASE","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",4,"GLY A 333;MET A  29;ALA A 331;ILE A 384","None","0.84A","4txnB-5vc2A:undetectable","4txnB-5vc2A:22.76"],["4TXN_C_URFC302_1","URIDINE PHOSPHORYLASE","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",4,"GLY A 333;MET A  29;ALA A 331;ILE A 384","None","0.81A","4txnC-5vc2A:undetectable","4txnC-5vc2A:22.76"],["4TXN_D_URFD302_1","URIDINE PHOSPHORYLASE","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",4,"GLY A 333;MET A  29;ALA A 331;ILE A 384","None","0.83A","4txnD-5vc2A:undetectable","4txnD-5vc2A:22.76"],["4U14_A_0HKA2000_2","MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARINIC ACETYLCHOLINE RECEPTOR M3","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",4,"ASN A  99;LEU A 194;PHE A 171;TYR A 142","None","1.41A","4u14A-5vc2A:undetectable","4u14A-5vc2A:21.57"],["4Y8W_C_STRC603_1","CYTOCHROME P450 21-HYDROXYLASE","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",5,"LEU A 297;VAL A 339;ILE A 337;ILE A 357;GLY A 356","None","0.94A","4y8wC-5vc2A:undetectable","4y8wC-5vc2A:22.71"],["4YDQ_B_HFGB802_1","PROLINE--TRNA LIGASE","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",3,"GLU A  19;THR A 338;HIS A  26","None","0.83A","4ydqB-5vc2A:undetectable","4ydqB-5vc2A:19.96"],["5IMS_B_ACTB713_0","ACETOLACTATE SYNTHASE CATALYTIC SUBUNIT, MITOCHONDRIAL","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",3,"GLY A 308;GLN A 291;LYS A 298","None","0.89A","5imsB-5vc2A:undetectable","5imsB-5vc2A:22.64"],["5NUN_A_Z80A201_1","BETA-LACTOGLOBULIN","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",5,"ALA A  88;ILE A 198;ASN A  84;PHE A  83;ALA A  79","None","0.89A","5nunA-5vc2A:undetectable","5nunA-5vc2A:12.47"],["5YCN_A_8LXA501_0","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","5vc2","SERINE HYDROXYMETHYLTRANSFERASE","Helicobacter pylori",6,"GLY A 378;TYR A 323;VAL A 339;ILE A 337;MET A  29;MET A 316","None","1.45A","5ycnA-5vc2A:undetectable","5ycnA-5vc2A:21.66"]]