SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ve2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_C_ESTC353_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 5ve2 ENOYL-COA HYDRATASE
(Pseudoalteromona
s
atlantica) 		5 / 12 LEU A  35
TYR A  32
GLY A 107
PHE A  60
VAL A  51
 LEU  A  35 ( 0.6A)
TYR  A  32 ( 1.3A)
GLY  A 107 ( 0.0A)
PHE  A  60 ( 1.3A)
VAL  A  51 ( 0.6A)
 1.10A 1fduC-5ve2A:
undetectable		 1fduC-5ve2A:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1502_0
(FERROCHELATASE)		 5ve2 ENOYL-COA HYDRATASE
(Pseudoalteromona
s
atlantica) 		4 / 8 ARG A 161
LEU A 163
VAL A 148
GLY A 149
 ARG  A 161 ( 0.6A)
LEU  A 163 ( 0.5A)
VAL  A 148 ( 0.6A)
GLY  A 149 ( 0.0A)
 1.02A 1hrkA-5ve2A:
undetectable		 1hrkA-5ve2A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5ve2 ENOYL-COA HYDRATASE
(Pseudoalteromona
s
atlantica) 		4 / 8 ARG A 161
LEU A 163
VAL A 148
GLY A 149
 ARG  A 161 ( 0.6A)
LEU  A 163 ( 0.5A)
VAL  A 148 ( 0.6A)
GLY  A 149 ( 0.0A)
 0.90A 2po5A-5ve2A:
undetectable		 2po5A-5ve2A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_B_QPSB1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 5ve2 ENOYL-COA HYDRATASE
(Pseudoalteromona
s
atlantica) 		5 / 10 VAL A 184
SER A  15
SER A   8
ASN A  11
ALA A 191
 VAL  A 184 ( 0.6A)
SER  A  15 ( 0.0A)
SER  A   8 ( 0.0A)
ASN  A  11 ( 0.6A)
ALA  A 191 ( 0.0A)
 1.47A 2x2iB-5ve2A:
undetectable		 2x2iB-5ve2A:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_G_CPFG1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 5ve2 ENOYL-COA HYDRATASE
(Pseudoalteromona
s
atlantica) 		3 / 3 ARG A 161
GLY A 160
SER A 140
 ARG  A 161 ( 0.6A)
GLY  A 160 ( 0.0A)
SER  A 140 ( 0.0A)
 0.60A 2xctB-5ve2A:
undetectable		 2xctB-5ve2A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_1
(16S RRNA METHYLASE)		 5ve2 ENOYL-COA HYDRATASE
(Pseudoalteromona
s
atlantica) 		4 / 5 ASN A  43
GLU A 137
THR A 109
SER A  42
 ASN  A  43 ( 0.6A)
GLU  A 137 ( 0.6A)
THR  A 109 ( 0.8A)
SER  A  42 (-0.0A)
 1.14A 3p2kC-5ve2A:
undetectable		 3p2kC-5ve2A:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AWU_A_4CHA502_0
(OXIDOREDUCTASE,
FMN-BINDING)		 5ve2 ENOYL-COA HYDRATASE
(Pseudoalteromona
s
atlantica) 		4 / 7 THR A  61
TYR A  32
LEU A  35
PHE A  60
 THR  A  61 ( 0.8A)
TYR  A  32 ( 1.3A)
LEU  A  35 ( 0.6A)
PHE  A  60 ( 1.3A)
 1.33A 4awuA-5ve2A:
undetectable		 4awuA-5ve2A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 5ve2 ENOYL-COA HYDRATASE
(Pseudoalteromona
s
atlantica) 		5 / 12 LEU A 144
GLY A 105
LEU A 156
GLY A 160
PRO A 136
 LEU  A 144 ( 0.6A)
GLY  A 105 ( 0.0A)
LEU  A 156 ( 0.5A)
GLY  A 160 ( 0.0A)
PRO  A 136 ( 1.1A)
 1.03A 4blvA-5ve2A:
undetectable		 4blvA-5ve2A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 5ve2 ENOYL-COA HYDRATASE
(Pseudoalteromona
s
atlantica) 		3 / 3 VAL A 106
ALA A 138
PHE A 129
 VAL  A 106 ( 0.6A)
ALA  A 138 ( 0.0A)
PHE  A 129 ( 1.3A)
 0.82A 4z4iA-5ve2A:
undetectable		 4z4iA-5ve2A:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS1_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5ve2 ENOYL-COA HYDRATASE
(Pseudoalteromona
s
atlantica) 		3 / 3 VAL A 106
ALA A 138
PHE A 129
 VAL  A 106 ( 0.6A)
ALA  A 138 ( 0.0A)
PHE  A 129 ( 1.3A)
 0.83A 5js1A-5ve2A:
undetectable		 5js1A-5ve2A:
15.25