SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ve3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		4 / 7 TYR B  17
PHE B 130
ILE B 137
GLY B 132
 None
 0.93A 11gsA-5ve3B:
undetectable		 11gsA-5ve3B:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FB7_A_ROCA100_1
(HIV-1 PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.90A 1fb7A-5ve3B:
undetectable		 1fb7A-5ve3B:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_2
(HIV-1 PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.80A 1hsgB-5ve3B:
undetectable		 1hsgB-5ve3B:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OHR_A_1UNA201_1
(ASPARTYLPROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 11 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.83A 1ohrA-5ve3B:
undetectable		 1ohrA-5ve3B:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.82A 1sdtB-5ve3B:
undetectable		 1sdtB-5ve3B:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.77A 1sduB-5ve3B:
undetectable		 1sduB-5ve3B:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_1
(HIV-1 PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 10 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.80A 2aquA-5ve3B:
undetectable		 2aquA-5ve3B:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_2
(HIV-1 PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 11 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.79A 2aquB-5ve3B:
undetectable		 2aquB-5ve3B:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_2
(POL POLYPROTEIN)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.77A 2avoB-5ve3B:
undetectable		 2avoB-5ve3B:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_3
(POL POLYPROTEIN)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.85A 2avvE-5ve3B:
undetectable		 2avvE-5ve3B:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BPX_B_MK1B902_2
(HIV-1 PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.86A 2bpxB-5ve3B:
undetectable		 2bpxB-5ve3B:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_1
(POL POLYPROTEIN)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.84A 2f80A-5ve3B:
undetectable		 2f80A-5ve3B:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_2
(POL POLYPROTEIN)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.78A 2f80B-5ve3B:
undetectable		 2f80B-5ve3B:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_1
(POL POLYPROTEIN)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.92A 2f81A-5ve3B:
undetectable		 2f81A-5ve3B:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_2
(POL POLYPROTEIN)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.93A 2f81B-5ve3B:
undetectable		 2f81B-5ve3B:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_1
(POL POLYPROTEIN)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.81A 2f8gA-5ve3B:
undetectable		 2f8gA-5ve3B:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_2
(POL PROTEIN)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 11 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.81A 2fxeB-5ve3B:
undetectable		 2fxeB-5ve3B:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_1
(PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.79A 2hs2A-5ve3B:
undetectable		 2hs2A-5ve3B:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_2
(PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.85A 2hs2B-5ve3B:
undetectable		 2hs2B-5ve3B:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4S_A_AB1A400_1
(PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.74A 2o4sA-5ve3B:
undetectable		 2o4sA-5ve3B:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4S_A_AB1A400_2
(PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.76A 2o4sB-5ve3B:
undetectable		 2o4sB-5ve3B:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_2
(MINERALOCORTICOID
RECEPTOR)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		4 / 5 LEU B   2
LEU B  19
LEU B   7
MET B 128
 None
 1.05A 2oaxF-5ve3B:
undetectable		 2oaxF-5ve3B:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.74A 2pymA-5ve3B:
undetectable		 2pymA-5ve3B:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.76A 2pynA-5ve3B:
undetectable		 2pynA-5ve3B:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_2
(PROTEASE RETROPEPSIN)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.68A 2qhcB-5ve3B:
undetectable		 2qhcB-5ve3B:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_2
(PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 11 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.73A 2r5qB-5ve3B:
undetectable		 2r5qB-5ve3B:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_1
(HIV-1 PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.76A 2z54A-5ve3B:
undetectable		 2z54A-5ve3B:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_B_SHHB301_1
(HISTONE DEACETYLASE
7A)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 8 HIS B  58
HIS B  60
ASP B 133
HIS B 174
GLY B 132
 FE  B 500 (-3.3A)
None
FE  B 500 (-3.1A)
None
None
 1.41A 3c0zB-5ve3B:
undetectable		 3c0zB-5ve3B:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_C_SHHC301_1
(HISTONE DEACETYLASE
7A)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		4 / 6 ASP B 144
HIS B  58
HIS B 114
ASP B  62
 None
FE  B 500 (-3.3A)
FE  B 500 (-3.3A)
None
 0.81A 3c0zC-5ve3B:
undetectable		 3c0zC-5ve3B:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYW_A_017A201_1
(HIV-1 PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.82A 3cywA-5ve3B:
undetectable		 3cywA-5ve3B:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYW_A_017A201_2
(HIV-1 PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.87A 3cywB-5ve3B:
undetectable		 3cywB-5ve3B:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_1
(HIV-1 PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.81A 3cyxA-5ve3B:
undetectable		 3cyxA-5ve3B:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D20_A_017A201_2
(HIV-1 PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.90A 3d20B-5ve3B:
undetectable		 3d20B-5ve3B:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_1
(PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 10 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.78A 3ekyA-5ve3B:
undetectable		 3ekyA-5ve3B:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_1
(PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		4 / 8 GLY B  88
ALA B  89
ASP B  90
ILE B  80
 None
 0.68A 3el0A-5ve3B:
undetectable		 3el0A-5ve3B:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_1
(PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 11 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.83A 3el1A-5ve3B:
undetectable		 3el1A-5ve3B:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_1
(PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 11 ALA B  89
ASP B  90
LEU B 230
VAL B  59
ILE B  80
 None
 0.87A 3em4A-5ve3B:
undetectable		 3em4A-5ve3B:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_1
(PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 11 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.89A 3em4A-5ve3B:
undetectable		 3em4A-5ve3B:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_1
(PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 11 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.78A 3em4U-5ve3B:
undetectable		 3em4U-5ve3B:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_A_EAAA212_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		4 / 7 TYR B  17
PHE B 130
ILE B 137
GLY B 132
 None
 0.99A 3gssA-5ve3B:
undetectable		 3gssA-5ve3B:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		4 / 7 TYR B  17
PHE B 130
ILE B 137
GLY B 132
 None
 1.00A 3gssB-5ve3B:
undetectable		 3gssB-5ve3B:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_2
(GAG-POL POLYPROTEIN)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.81A 3jvyB-5ve3B:
undetectable		 3jvyB-5ve3B:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_3
(HIV-1 PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.90A 3k4vD-5ve3B:
undetectable		 3k4vD-5ve3B:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_1
(HIV-1 PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.72A 3lzsA-5ve3B:
undetectable		 3lzsA-5ve3B:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_2
(HIV-1 PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.83A 3lzsB-5ve3B:
undetectable		 3lzsB-5ve3B:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_1
(HIV-1 PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.80A 3lzuA-5ve3B:
undetectable		 3lzuA-5ve3B:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_A_EAAA210_1
(GLUTATHIONE
S-TRANSFERASE P)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		4 / 8 TYR B  17
PHE B 130
ILE B 137
GLY B 132
 None
 0.96A 3n9jA-5ve3B:
undetectable		 3n9jA-5ve3B:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_2
(PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.92A 3ndtD-5ve3B:
undetectable		 3ndtD-5ve3B:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_1
(PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.80A 3nduA-5ve3B:
undetectable		 3nduA-5ve3B:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_2
(PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.79A 3nduB-5ve3B:
undetectable		 3nduB-5ve3B:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_2
(PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.89A 3nduD-5ve3B:
undetectable		 3nduD-5ve3B:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_1
(PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.86A 3ndwA-5ve3B:
undetectable		 3ndwA-5ve3B:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_1
(PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.88A 3ndxA-5ve3B:
undetectable		 3ndxA-5ve3B:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_2
(PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 11 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.84A 3ndxB-5ve3B:
undetectable		 3ndxB-5ve3B:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_1
(HIV-1 PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.85A 3oxxC-5ve3B:
undetectable		 3oxxC-5ve3B:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_2
(PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.93A 3pwmB-5ve3B:
undetectable		 3pwmB-5ve3B:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_1
(PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.90A 3pwrA-5ve3B:
undetectable		 3pwrA-5ve3B:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_1
(PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.81A 3tkgA-5ve3B:
undetectable		 3tkgA-5ve3B:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_1
(PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.88A 3tkgC-5ve3B:
undetectable		 3tkgC-5ve3B:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_1
(PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.85A 3tkwA-5ve3B:
undetectable		 3tkwA-5ve3B:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_A_SHHA700_1
(HISTONE DEACETYLASE
8)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 10 HIS B  58
HIS B  60
ASP B 133
HIS B 174
GLY B 132
 FE  B 500 (-3.3A)
None
FE  B 500 (-3.1A)
None
None
 1.44A 4bz6A-5ve3B:
undetectable		 4bz6A-5ve3B:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_B_SHHB700_1
(HISTONE DEACETYLASE
8)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 HIS B  58
HIS B  60
ASP B 133
HIS B 174
GLY B 132
 FE  B 500 (-3.3A)
None
FE  B 500 (-3.1A)
None
None
 1.43A 4bz6A-5ve3B:
undetectable
4bz6B-5ve3B:
undetectable		 4bz6A-5ve3B:
23.08
4bz6B-5ve3B:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_C_SHHC700_1
(HISTONE DEACETYLASE
8)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 HIS B 114
GLY B 132
HIS B  60
ASP B  62
HIS B  63
 FE  B 500 (-3.3A)
None
None
None
None
 1.27A 4bz6C-5ve3B:
undetectable		 4bz6C-5ve3B:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_D_SHHD700_1
(HISTONE DEACETYLASE
8)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 10 HIS B  58
HIS B  60
ASP B 133
HIS B 174
GLY B 132
 FE  B 500 (-3.3A)
None
FE  B 500 (-3.1A)
None
None
 1.45A 4bz6D-5ve3B:
undetectable		 4bz6D-5ve3B:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_1
(PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.76A 4hlaA-5ve3B:
undetectable		 4hlaA-5ve3B:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_2
(PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 11 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.77A 4hlaB-5ve3B:
undetectable		 4hlaB-5ve3B:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN0_A_MTXA301_1
(FOLATE RECEPTOR BETA)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 PHE B 332
ASP B 307
ARG B 290
ARG B 300
GLY B 299
 None
 1.31A 4kn0A-5ve3B:
0.0		 4kn0A-5ve3B:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MGH_A_ACTA1320_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 5 VAL B 271
LEU B 304
ILE B 292
LEU B 291
ARG B 290
 None
 1.16A 4mghA-5ve3B:
undetectable		 4mghA-5ve3B:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_B_AC2B301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 10 SER B 320
VAL B 311
GLU B 255
ASP B 272
ILE B 270
 None
 1.18A 5i3cB-5ve3B:
undetectable		 5i3cB-5ve3B:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_B_BEZB306_0
(BETA-LACTAMASE VIM-2)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		3 / 3 HIS B  60
ASN B 225
ALA B  86
 None
 0.71A 5n4tB-5ve3B:
6.0		 5n4tB-5ve3B:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NN8_A_ACRA1015_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 ASP B  62
ILE B  30
ASP B  31
ASP B 133
LEU B 136
 None
None
None
FE  B 500 (-3.1A)
None
 1.50A 5nn8A-5ve3B:
undetectable		 5nn8A-5ve3B:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA601_0
(THIOCYANATE
DEHYDROGENASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		3 / 3 HIS B 174
ASP B  62
HIS B  63
 None
 0.78A 5oexA-5ve3B:
undetectable		 5oexA-5ve3B:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA604_0
(THIOCYANATE
DEHYDROGENASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		3 / 3 HIS B 114
HIS B  58
HIS B  60
 FE  B 500 (-3.3A)
FE  B 500 (-3.3A)
None
 1.02A 5oexA-5ve3B:
undetectable		 5oexA-5ve3B:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB601_0
(THIOCYANATE
DEHYDROGENASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		3 / 3 HIS B 174
ASP B  62
HIS B  63
 None
 0.75A 5oexB-5ve3B:
undetectable		 5oexB-5ve3B:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC601_0
(THIOCYANATE
DEHYDROGENASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		3 / 3 HIS B 174
ASP B  62
HIS B  63
 None
 0.72A 5oexC-5ve3B:
undetectable		 5oexC-5ve3B:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD601_0
(THIOCYANATE
DEHYDROGENASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		3 / 3 HIS B 174
ASP B  62
HIS B  63
 None
 0.69A 5oexD-5ve3B:
undetectable		 5oexD-5ve3B:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDZ_A_ADNA905_1
(ATP-CITRATE SYNTHASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		4 / 6 ARG B  39
THR B  16
ASP B  31
LEU B  29
 None
 1.19A 5tdzA-5ve3B:
undetectable		 5tdzA-5ve3B:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_B_ADNB503_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		4 / 5 LEU B 297
VAL B 271
GLU B 269
LEU B 304
 None
 0.75A 5xooB-5ve3B:
undetectable		 5xooB-5ve3B:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_0
(PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.92A 6dgxA-5ve3B:
undetectable		 6dgxA-5ve3B:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_0
(PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.92A 6dh6A-5ve3B:
undetectable		 6dh6A-5ve3B:
11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ1_B_AB1B201_0
(HIV-1 PROTEASE)		 5ve3 BPPRF
(Paraburkholderia
phytofirmans) 		5 / 12 GLY B  88
ALA B  89
ASP B  90
VAL B  59
ILE B  80
 None
 0.71A 6dj1A-5ve3B:
undetectable		 6dj1A-5ve3B:
12.68