SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ve6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NK2_X_LDPX433_1 (6-HYDROXY-L-NICOTINE OXIDASE)	5ve6	TYROSINE-PROTEIN KINASE SGK223 (Homo sapiens)	4 / 7	ASN A1046 LEU A1125 LEU A1383 PHE A1045	None	0.97A	3nk2X-5ve6A: undetectable	3nk2X-5ve6A: 21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ODO_B_FK5B203_1 (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE SLYD)	5ve6	TYROSINE-PROTEIN KINASE SGK223 (Homo sapiens)	5 / 10	ASP A1145 LEU A1260 LEU A1129 ILE A1214 LEU A1133	None	1.09A	4odoB-5ve6A: undetectable	4odoB-5ve6A: 14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N0S_B_SAMB501_0 (PEPTIDE N-METHYLTRANSFERASE)	5ve6	TYROSINE-PROTEIN KINASE SGK223 (Homo sapiens)	5 / 12	ILE A1318 HIS A1143 PHE A1252 ILE A1316 ALA A1321	None	1.13A	5n0sB-5ve6A: undetectable	5n0sB-5ve6A: 22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NWU_A_ACAA18_2 (WTFP-TAG,GP41)	5ve6	TYROSINE-PROTEIN KINASE SGK223 (Homo sapiens)	3 / 3	LEU A1329 LEU A1383 TRP A1382	None	0.82A	5nwuA-5ve6A: undetectable	5nwuA-5ve6A: 5.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X6Y_C_SAMC902_0 (MRNA CAPPING ENZYME P5)	5ve6	TYROSINE-PROTEIN KINASE SGK223 (Homo sapiens)	5 / 12	LEU A1287 TYR A1262 ALA A1304 HIS A1305 GLU A1149	None	1.29A	5x6yC-5ve6A: undetectable	5x6yC-5ve6A: 19.19

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3NK2_X_LDPX433_1","6-HYDROXY-L-NICOTINE OXIDASE","5ve6","TYROSINE-PROTEIN KINASE SGK223","Homo sapiens",4,"ASN A1046;LEU A1125;LEU A1383;PHE A1045","None","0.97A","3nk2X-5ve6A:undetectable","3nk2X-5ve6A:21.37"],["4ODO_B_FK5B203_1","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE SLYD","5ve6","TYROSINE-PROTEIN KINASE SGK223","Homo sapiens",5,"ASP A1145;LEU A1260;LEU A1129;ILE A1214;LEU A1133","None","1.09A","4odoB-5ve6A:undetectable","4odoB-5ve6A:14.40"],["5N0S_B_SAMB501_0","PEPTIDE N-METHYLTRANSFERASE","5ve6","TYROSINE-PROTEIN KINASE SGK223","Homo sapiens",5,"ILE A1318;HIS A1143;PHE A1252;ILE A1316;ALA A1321","None","1.13A","5n0sB-5ve6A:undetectable","5n0sB-5ve6A:22.92"],["5NWU_A_ACAA18_2","WTFP-TAG,GP41","5ve6","TYROSINE-PROTEIN KINASE SGK223","Homo sapiens",3,"LEU A1329;LEU A1383;TRP A1382","None","0.82A","5nwuA-5ve6A:undetectable","5nwuA-5ve6A:5.94"],["5X6Y_C_SAMC902_0","MRNA CAPPING ENZYME P5","5ve6","TYROSINE-PROTEIN KINASE SGK223","Homo sapiens",5,"LEU A1287;TYR A1262;ALA A1304;HIS A1305;GLU A1149","None","1.29A","5x6yC-5ve6A:undetectable","5x6yC-5ve6A:19.19"]]