SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5veb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2503_0
(FERROCHELATASE)		 5veb CADHERIN-6
(Homo
sapiens) 		4 / 4 LEU X 566
PRO X 567
LEU X 527
ARG X 552
 None
A2G  X2002 ( 4.9A)
None
None
 1.41A 1hrkB-5vebX:
undetectable		 1hrkB-5vebX:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5veb CADHERIN-6
(Homo
sapiens) 		5 / 10 VAL X 568
LEU X 527
LEU X 550
GLY X 548
ALA X 547
 None
 1.12A 1pxxA-5vebX:
undetectable		 1pxxA-5vebX:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_C_DIFC2701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5veb CADHERIN-6
(Homo
sapiens) 		5 / 12 VAL X 568
LEU X 527
SER X 526
GLY X 548
ALA X 547
 None
 0.93A 1pxxC-5vebX:
undetectable		 1pxxC-5vebX:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_D_DIFD3701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5veb CADHERIN-6
(Homo
sapiens) 		5 / 10 VAL X 568
LEU X 527
LEU X 550
GLY X 548
ALA X 547
 None
 1.13A 1pxxD-5vebX:
undetectable		 1pxxD-5vebX:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T03_P_TFOP822_1
(POL POLYPROTEIN
SYNTHETIC
OLIGONUCLEOTIDE
PRIMER)		 5veb CADHERIN-6
(Homo
sapiens) 		4 / 7 ASP X 572
TYR X 575
ASP X 574
HIS X 521
 None
 1.48A 1t03A-5vebX:
undetectable		 1t03A-5vebX:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1604_0
(FERROCHELATASE)		 5veb CADHERIN-6
(Homo
sapiens) 		4 / 4 LEU X 566
PRO X 567
LEU X 527
ARG X 552
 None
A2G  X2002 ( 4.9A)
None
None
 1.40A 2hrcB-5vebX:
undetectable		 2hrcB-5vebX:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5veb CADHERIN-6
(Homo
sapiens) 		5 / 11 VAL X 568
LEU X 527
SER X 526
GLY X 548
ALA X 547
 None
 1.01A 3n8yA-5vebX:
undetectable		 3n8yA-5vebX:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5veb CADHERIN-6
(Homo
sapiens) 		6 / 12 VAL X 568
LEU X 527
SER X 526
LEU X 550
GLY X 548
ALA X 547
 None
 1.06A 4otyA-5vebX:
undetectable		 4otyA-5vebX:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5veb CADHERIN-6
(Homo
sapiens) 		6 / 12 VAL X 568
LEU X 527
SER X 526
LEU X 550
GLY X 548
ALA X 547
 None
 1.06A 4otyB-5vebX:
undetectable		 4otyB-5vebX:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5veb CADHERIN-6
(Homo
sapiens) 		5 / 12 VAL X 568
LEU X 527
SER X 526
GLY X 548
ALA X 547
 None
 0.99A 4rrwA-5vebX:
undetectable		 4rrwA-5vebX:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5veb CADHERIN-6
(Homo
sapiens) 		5 / 12 VAL X 568
LEU X 527
SER X 526
GLY X 548
ALA X 547
 None
 0.98A 4rrwB-5vebX:
undetectable		 4rrwB-5vebX:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5veb CADHERIN-6
(Homo
sapiens) 		6 / 12 VAL X 568
LEU X 527
SER X 526
LEU X 550
GLY X 548
ALA X 547
 None
 1.11A 4rrwC-5vebX:
undetectable		 4rrwC-5vebX:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_A_LURA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5veb CADHERIN-6
(Homo
sapiens) 		5 / 12 VAL X 568
LEU X 527
LEU X 550
GLY X 548
ALA X 547
 None
 1.10A 4rrxA-5vebX:
undetectable		 4rrxA-5vebX:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_B_LURB706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5veb CADHERIN-6
(Homo
sapiens) 		5 / 12 VAL X 568
LEU X 527
LEU X 550
GLY X 548
ALA X 547
 None
 1.10A 4rrxB-5vebX:
undetectable		 4rrxB-5vebX:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5veb CADHERIN-6
(Homo
sapiens) 		5 / 12 VAL X 568
LEU X 527
SER X 526
GLY X 548
ALA X 547
 None
 0.99A 4rrzA-5vebX:
undetectable		 4rrzA-5vebX:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5veb CADHERIN-6
(Homo
sapiens) 		5 / 12 VAL X 568
LEU X 527
SER X 526
GLY X 548
ALA X 547
 None
 0.98A 4rrzB-5vebX:
undetectable		 4rrzB-5vebX:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5veb CADHERIN-6
(Homo
sapiens) 		6 / 12 VAL X 568
LEU X 527
SER X 526
LEU X 550
GLY X 548
ALA X 547
 None
 1.11A 4rrzC-5vebX:
undetectable		 4rrzC-5vebX:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_B_FLPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5veb CADHERIN-6
(Homo
sapiens) 		5 / 12 VAL X 568
LEU X 527
SER X 526
GLY X 548
ALA X 547
 None
 1.06A 5jvzB-5vebX:
undetectable		 5jvzB-5vebX:
12.62