SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5veg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_A_RBFA301_1
(PROTEIN (FLAVODOXIN))		 5veg FLAVODOXIN
(Lactobacillus
reuteri) 		6 / 7 THR A  12
ASN A  14
THR A  58
GLY A  91
ASP A  92
TYR A  95
 FMN  A 201 (-3.6A)
FMN  A 201 (-3.8A)
FMN  A 201 (-3.8A)
FMN  A 201 (-3.4A)
None
FMN  A 201 (-3.4A)
 0.44A 1bu5A-5vegA:
22.6		 1bu5A-5vegA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_B_RBFB302_1
(PROTEIN (FLAVODOXIN))		 5veg FLAVODOXIN
(Lactobacillus
reuteri) 		6 / 8 THR A  12
ASN A  14
THR A  58
GLY A  91
ASP A  92
TYR A  95
 FMN  A 201 (-3.6A)
FMN  A 201 (-3.8A)
FMN  A 201 (-3.8A)
FMN  A 201 (-3.4A)
None
FMN  A 201 (-3.4A)
 0.42A 1bu5B-5vegA:
22.5		 1bu5B-5vegA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A933_1
(ANDROGEN RECEPTOR)		 5veg FLAVODOXIN
(Lactobacillus
reuteri) 		5 / 10 ILE A 133
GLY A  89
ASN A 100
ASN A  14
GLU A  17
 None
None
FMN  A 201 (-4.6A)
FMN  A 201 (-3.8A)
None
 1.21A 2piwA-5vegA:
undetectable		 2piwA-5vegA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_2
(CYTOCHROME P450 2R1)		 5veg FLAVODOXIN
(Lactobacillus
reuteri) 		3 / 3 MET A  64
VAL A  54
GLU A  67
 None
 0.77A 3c6gA-5vegA:
undetectable		 3c6gA-5vegA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_B_FLPB701_1
(CYCLOOXYGENASE-2)		 5veg FLAVODOXIN
(Lactobacillus
reuteri) 		5 / 11 VAL A  22
LEU A  26
VAL A 122
GLY A  89
ALA A  88
 None
 1.21A 3pghB-5vegA:
undetectable		 3pghB-5vegA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 5veg FLAVODOXIN
(Lactobacillus
reuteri) 		5 / 12 TYR A  85
VAL A 103
ALA A 113
PHE A  71
PHE A  46
 None
 1.30A 3qowA-5vegA:
2.5		 3qowA-5vegA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_B_LLLB301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5veg FLAVODOXIN
(Lactobacillus
reuteri) 		4 / 7 TYR A  95
GLU A  61
ASP A  60
GLU A  66
 FMN  A 201 (-3.4A)
None
FMN  A 201 ( 4.7A)
None
 1.27A 6mn5B-5vegA:
undetectable		 6mn5B-5vegA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_C_LLLC301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5veg FLAVODOXIN
(Lactobacillus
reuteri) 		4 / 6 TYR A  95
GLU A  61
ASP A  60
GLU A  66
 FMN  A 201 (-3.4A)
None
FMN  A 201 ( 4.7A)
None
 1.46A 6mn5C-5vegA:
undetectable		 6mn5C-5vegA:
20.13