SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5veh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KW0_A_H4BA429_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 5veh KYNURENINE
AMINOTRANSFERASE
(Aedes
aegypti) 		5 / 12 LEU A 274
LEU A 105
LEU A  86
THR A 117
TYR A  90
 None
 1.32A 1kw0A-5vehA:
undetectable		 1kw0A-5vehA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMT_A_H4BA1426_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 5veh KYNURENINE
AMINOTRANSFERASE
(Aedes
aegypti) 		5 / 11 LEU A 274
LEU A 105
LEU A  86
THR A 117
TYR A  90
 None
 1.29A 1mmtA-5vehA:
undetectable		 1mmtA-5vehA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_ACTH611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 5veh KYNURENINE
AMINOTRANSFERASE
(Aedes
aegypti) 		4 / 6 LEU A 422
TRP A 425
LEU A 355
PHE A 373
 None
 1.38A 1ru9H-5vehA:
undetectable
1ru9L-5vehA:
undetectable		 1ru9H-5vehA:
19.52
1ru9L-5vehA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_L_ACTL611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 5veh KYNURENINE
AMINOTRANSFERASE
(Aedes
aegypti) 		4 / 6 LEU A 422
TRP A 425
LEU A 355
PHE A 373
 None
 1.46A 1rukH-5vehA:
undetectable
1rukL-5vehA:
undetectable		 1rukH-5vehA:
19.52
1rukL-5vehA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOZ_A_CIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5veh KYNURENINE
AMINOTRANSFERASE
(Aedes
aegypti) 		5 / 12 ALA A 267
ILE A 250
VAL A 219
ILE A 237
MET A 243
 None
 1.02A 1xozA-5vehA:
undetectable		 1xozA-5vehA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_2
(ADENOSYLHOMOCYSTEINA
SE)		 5veh KYNURENINE
AMINOTRANSFERASE
(Aedes
aegypti) 		4 / 5 GLN A 278
THR A  74
HIS A  79
HIS A 281
 None
 1.36A 3g1uC-5vehA:
undetectable		 3g1uC-5vehA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID6_C_SAMC301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 5veh KYNURENINE
AMINOTRANSFERASE
(Aedes
aegypti) 		5 / 12 GLY A 109
ALA A 113
GLU A 112
ILE A 264
GLN A 293
 LLP  A 255 ( 3.2A)
None
None
None
None
 0.99A 3id6C-5vehA:
undetectable		 3id6C-5vehA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 5veh KYNURENINE
AMINOTRANSFERASE
(Aedes
aegypti) 		3 / 3 LEU A  89
TRP A 266
GLY A 251
 None
 0.74A 3l35A-5vehA:
undetectable
3l35H-5vehA:
undetectable		 3l35A-5vehA:
6.62
3l35H-5vehA:
3.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 5veh KYNURENINE
AMINOTRANSFERASE
(Aedes
aegypti) 		3 / 3 LEU A  89
TRP A 266
GLY A 251
 None
 0.76A 3l35B-5vehA:
undetectable
3l35K-5vehA:
undetectable		 3l35B-5vehA:
6.62
3l35K-5vehA:
3.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_B_SAMB401_0
(MNMC2)		 5veh KYNURENINE
AMINOTRANSFERASE
(Aedes
aegypti) 		5 / 12 GLY A 345
GLY A 196
LEU A 195
ASN A 193
LEU A 321
 None
None
None
LLP  A 255 ( 3.9A)
None
 1.26A 3vywB-5vehA:
undetectable		 3vywB-5vehA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_C_MIYC392_1
(TETX2 PROTEIN)		 5veh KYNURENINE
AMINOTRANSFERASE
(Aedes
aegypti) 		5 / 12 PRO A 140
GLU A 139
VAL A 122
ILE A 118
ILE A 130
 None
 1.49A 4a99A-5vehA:
undetectable
4a99C-5vehA:
undetectable		 4a99A-5vehA:
22.22
4a99C-5vehA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 5veh KYNURENINE
AMINOTRANSFERASE
(Aedes
aegypti) 		5 / 12 TYR A  90
GLY A 265
GLY A 254
LEU A 105
GLY A  78
 None
None
LLP  A 255 ( 2.4A)
None
None
 1.10A 4blvA-5vehA:
3.8		 4blvA-5vehA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_B_SHHB408_1
(HISTONE DEACETYLASE
2)		 5veh KYNURENINE
AMINOTRANSFERASE
(Aedes
aegypti) 		5 / 11 PRO A 194
ASP A 136
PHE A 391
ASP A 370
GLY A 400
 None
 1.35A 4lxzB-5vehA:
2.7		 4lxzB-5vehA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5veh KYNURENINE
AMINOTRANSFERASE
(Aedes
aegypti) 		5 / 10 THR A 256
GLU A 222
LEU A  86
VAL A  94
LEU A  93
 LLP  A 255 ( 4.4A)
None
None
None
None
 1.08A 4r3aB-5vehA:
undetectable		 4r3aB-5vehA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5veh KYNURENINE
AMINOTRANSFERASE
(Aedes
aegypti) 		4 / 4 LEU A 178
TYR A 138
PRO A 149
ILE A 148
 None
 1.26A 5esgA-5vehA:
undetectable		 5esgA-5vehA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5veh KYNURENINE
AMINOTRANSFERASE
(Aedes
aegypti) 		3 / 3 LEU A 321
TYR A  49
SER A 258
 None
None
LLP  A 255 ( 4.3A)
 0.76A 5iktA-5vehA:
undetectable		 5iktA-5vehA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_A_ASCA502_0
(OS09G0567300 PROTEIN)		 5veh KYNURENINE
AMINOTRANSFERASE
(Aedes
aegypti) 		4 / 5 GLU A  29
PRO A 387
PHE A 391
ARG A 405
 None
 1.45A 5jcnA-5vehA:
0.5		 5jcnA-5vehA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_B_ASCB502_0
(OS09G0567300 PROTEIN)		 5veh KYNURENINE
AMINOTRANSFERASE
(Aedes
aegypti) 		4 / 6 GLU A  29
PRO A 387
PHE A 391
ARG A 405
 None
 1.49A 5jcnB-5vehA:
undetectable		 5jcnB-5vehA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KXI_D_NCTD402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 5veh KYNURENINE
AMINOTRANSFERASE
(Aedes
aegypti) 		4 / 8 TYR A  54
THR A 256
TYR A 313
LEU A 259
 None
LLP  A 255 ( 4.4A)
None
None
 1.33A 5kxiD-5vehA:
undetectable
5kxiE-5vehA:
undetectable		 5kxiD-5vehA:
20.13
5kxiE-5vehA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		 5veh KYNURENINE
AMINOTRANSFERASE
(Aedes
aegypti) 		4 / 8 SER A 258
PRO A  52
TYR A  54
SER A 318
 LLP  A 255 ( 4.3A)
None
None
BR  A 501 ( 4.9A)
 1.12A 5l1fA-5vehA:
undetectable
5l1fB-5vehA:
4.0		 5l1fA-5vehA:
19.16
5l1fB-5vehA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_A_ACRA1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)		 5veh KYNURENINE
AMINOTRANSFERASE
(Aedes
aegypti) 		4 / 6 GLU A 320
PHE A 314
TYR A 313
PHE A 409
 None
 1.33A 5lrbA-5vehA:
undetectable		 5lrbA-5vehA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_B_ACRB1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)		 5veh KYNURENINE
AMINOTRANSFERASE
(Aedes
aegypti) 		5 / 9 GLU A 320
PHE A 257
THR A 256
TYR A 313
GLY A 319
 None
None
LLP  A 255 ( 4.4A)
None
BR  A 501 ( 4.2A)
 1.49A 5lrbB-5vehA:
0.0		 5lrbB-5vehA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5veh KYNURENINE
AMINOTRANSFERASE
(Aedes
aegypti) 		4 / 4 GLY A 120
ALA A 116
MET A 141
THR A 107
 None
 1.37A 5n0sB-5vehA:
1.5		 5n0sB-5vehA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_E_DVAE7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 5veh KYNURENINE
AMINOTRANSFERASE
(Aedes
aegypti) 		3 / 3 TYR A 268
SER A  87
TRP A 244
 None
 0.75A 5n8jB-5vehA:
undetectable		 5n8jB-5vehA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_E_DVAE7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 5veh KYNURENINE
AMINOTRANSFERASE
(Aedes
aegypti) 		3 / 3 TYR A 268
SER A  91
TRP A 244
 None
 1.07A 5n8jB-5vehA:
undetectable		 5n8jB-5vehA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_O_DVAO7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 5veh KYNURENINE
AMINOTRANSFERASE
(Aedes
aegypti) 		3 / 3 TYR A 268
SER A  87
TRP A 244
 None
 0.71A 5n8jA-5vehA:
undetectable		 5n8jA-5vehA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_O_DVAO7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 5veh KYNURENINE
AMINOTRANSFERASE
(Aedes
aegypti) 		3 / 3 TYR A 268
SER A  91
TRP A 244
 None
 1.01A 5n8jA-5vehA:
undetectable		 5n8jA-5vehA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_P_DVAP5_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 5veh KYNURENINE
AMINOTRANSFERASE
(Aedes
aegypti) 		3 / 3 TYR A 268
SER A  87
TRP A 244
 None
 0.73A 5n8jD-5vehA:
undetectable		 5n8jD-5vehA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_P_DVAP5_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 5veh KYNURENINE
AMINOTRANSFERASE
(Aedes
aegypti) 		3 / 3 TYR A 268
SER A  91
TRP A 244
 None
 0.99A 5n8jD-5vehA:
undetectable		 5n8jD-5vehA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 5veh KYNURENINE
AMINOTRANSFERASE
(Aedes
aegypti) 		5 / 12 PRO A 270
ILE A 250
LEU A 273
ILE A 188
THR A 190
 None
 1.30A 5tiwB-5vehA:
undetectable		 5tiwB-5vehA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_0
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 5veh KYNURENINE
AMINOTRANSFERASE
(Aedes
aegypti) 		5 / 12 PHE A 134
GLU A 132
PRO A 149
THR A  23
GLY A  21
 None
 1.49A 5xioA-5vehA:
undetectable		 5xioA-5vehA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EUQ_A_DXCA502_0
(MULTIDRUG
TRANSPORTER MDFA)		 5veh KYNURENINE
AMINOTRANSFERASE
(Aedes
aegypti) 		5 / 11 MET A 337
LEU A 332
GLY A  45
LEU A 422
MET A 328
 None
 1.38A 6euqA-5vehA:
undetectable		 6euqA-5vehA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNR_A_6J3A201_0
(TRANSTHYRETIN)		 5veh KYNURENINE
AMINOTRANSFERASE
(Aedes
aegypti) 		4 / 4 LYS A 417
LEU A  40
ALA A 419
LEU A 383
 None
 1.47A 6gnrA-5vehA:
undetectable		 6gnrA-5vehA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNR_B_6J3B201_0
(TRANSTHYRETIN)		 5veh KYNURENINE
AMINOTRANSFERASE
(Aedes
aegypti) 		4 / 4 LYS A 417
LEU A  40
ALA A 419
LEU A 383
 None
 1.46A 6gnrB-5vehA:
undetectable		 6gnrB-5vehA:
15.49