SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vem'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEA_A_ACAA90_1
(PLASMINOGEN)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		4 / 8 ASP A 191
ASP A  36
TYR A  42
ARG A  39
 ZN  A 502 (-2.0A)
ZN  A 501 (-2.0A)
None
None
 1.35A 1ceaA-5vemA:
undetectable
1ceaB-5vemA:
undetectable		 1ceaA-5vemA:
14.42
1ceaB-5vemA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEA_B_ACAB90_1
(PLASMINOGEN)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		4 / 7 ASP A 191
ASP A  36
TYR A  42
ARG A  39
 ZN  A 502 (-2.0A)
ZN  A 501 (-2.0A)
None
None
 1.39A 1ceaB-5vemA:
undetectable		 1ceaB-5vemA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_A_AMHA90_1
(PLASMINOGEN)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		4 / 7 ASP A 191
ASP A  36
TYR A  42
ARG A  39
 ZN  A 502 (-2.0A)
ZN  A 501 (-2.0A)
None
None
 1.40A 1cebA-5vemA:
undetectable		 1cebA-5vemA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_B_AMHB90_1
(PLASMINOGEN)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		4 / 7 ASP A 191
ASP A  36
TYR A  42
ARG A  39
 ZN  A 502 (-2.0A)
ZN  A 501 (-2.0A)
None
None
 1.35A 1cebB-5vemA:
undetectable		 1cebB-5vemA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_A_PPFA410_1
(PHOSPHONOACETATE
HYDROLASE)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		5 / 5 THR A  72
ASP A 191
HIS A 195
HIS A 239
HIS A 339
 ZN  A 501 (-2.4A)
ZN  A 502 (-2.0A)
ZN  A 502 (-3.2A)
ZN  A 501 (-3.1A)
ZN  A 502 (-3.2A)
 0.36A 1ei6A-5vemA:
27.9		 1ei6A-5vemA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_C_PPFC413_1
(PHOSPHONOACETATE
HYDROLASE)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		6 / 8 ASP A  36
THR A  72
ASP A 191
HIS A 195
HIS A 239
HIS A 339
 ZN  A 501 (-2.0A)
ZN  A 501 (-2.4A)
ZN  A 502 (-2.0A)
ZN  A 502 (-3.2A)
ZN  A 501 (-3.1A)
ZN  A 502 (-3.2A)
 0.41A 1ei6C-5vemA:
27.9		 1ei6C-5vemA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_D_PPFD412_1
(PHOSPHONOACETATE
HYDROLASE)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		4 / 8 THR A  72
ASP A 191
HIS A 195
HIS A 339
 ZN  A 501 (-2.4A)
ZN  A 502 (-2.0A)
ZN  A 502 (-3.2A)
ZN  A 502 (-3.2A)
 0.37A 1ei6D-5vemA:
8.1		 1ei6D-5vemA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA652_1
(AMYLOMALTASE)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		4 / 6 TYR A 341
GLY A 340
GLY A 337
SER A 267
 None
 0.97A 1eswA-5vemA:
undetectable		 1eswA-5vemA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		6 / 12 HIS A 195
THR A 242
GLY A 337
GLY A 198
GLY A 194
GLY A 340
 ZN  A 502 (-3.2A)
None
None
None
None
None
 1.27A 1n2xB-5vemA:
undetectable		 1n2xB-5vemA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_A_DEXA1999_1
(GLUCOCORTICOID
RECEPTOR)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		5 / 12 MET A 193
LEU A 197
LEU A 336
GLY A 337
GLN A 243
 None
 1.46A 1p93A-5vemA:
undetectable		 1p93A-5vemA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		5 / 12 ILE A 170
ALA A 137
LEU A 233
ILE A 235
PHE A 174
 None
 1.22A 1xzxX-5vemA:
undetectable		 1xzxX-5vemA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		5 / 12 ILE A 170
ALA A 137
LEU A 233
ILE A 235
PHE A 174
 None
 1.23A 1y0xX-5vemA:
undetectable		 1y0xX-5vemA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1434_1
(CHITINASE)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		3 / 3 TRP A 124
THR A  81
TYR A  77
 None
 1.18A 2a3aA-5vemA:
undetectable		 2a3aA-5vemA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2434_1
(CHITINASE)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		3 / 3 TRP A 124
THR A  81
TYR A  77
 None
 1.18A 2a3aB-5vemA:
undetectable		 2a3aB-5vemA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		3 / 3 TRP A 124
THR A  81
TYR A  77
 None
 1.16A 2a3bA-5vemA:
undetectable		 2a3bA-5vemA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		4 / 6 TYR A 157
GLY A  37
PHE A  35
SER A 237
 None
ZN  A 501 ( 4.9A)
None
None
 1.21A 2a3cA-5vemA:
undetectable		 2a3cA-5vemA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2434_1
(CHITINASE)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		4 / 6 TYR A 157
GLY A  37
PHE A  35
SER A 237
 None
ZN  A 501 ( 4.9A)
None
None
 1.30A 2a3cB-5vemA:
undetectable		 2a3cB-5vemA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA502_1
(CYTOCHROME P450 2B4)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		5 / 12 PHE A 359
LEU A 182
LEU A 184
ILE A 234
LEU A 373
 None
 1.05A 2bdmA-5vemA:
undetectable		 2bdmA-5vemA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		5 / 12 VAL A  59
ILE A 234
THR A 236
LEU A  32
LEU A 399
 None
 1.02A 2jn3A-5vemA:
undetectable		 2jn3A-5vemA:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BU1_A_HSMA301_1
(LIPOCALIN)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		4 / 7 VAL A  91
TYR A 307
ILE A 317
ASP A 265
 None
 1.11A 3bu1A-5vemA:
undetectable		 3bu1A-5vemA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_2
(GLUCOCORTICOID
RECEPTOR)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		3 / 3 MET A 348
CYH A 244
PRO A 268
 None
 1.22A 3h52C-5vemA:
undetectable		 3h52C-5vemA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEC_A_STIA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		4 / 4 LEU A 182
MET A 155
ILE A 235
ASP A 238
 None
None
None
ZN  A 501 (-2.3A)
 1.44A 3hecA-5vemA:
undetectable		 3hecA-5vemA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OI8_A_ADNA2_1
(UNCHARACTERIZED
PROTEIN)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		4 / 6 ASN A 338
HIS A 195
PRO A 199
ASP A  36
 None
ZN  A 502 (-3.2A)
None
ZN  A 501 (-2.0A)
 1.05A 3oi8A-5vemA:
undetectable		 3oi8A-5vemA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T01_A_PPFA503_1
(PHOSPHONOACETATE
HYDROLASE)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		4 / 7 THR A  72
ASP A 191
HIS A 195
HIS A 339
 ZN  A 501 (-2.4A)
ZN  A 502 (-2.0A)
ZN  A 502 (-3.2A)
ZN  A 502 (-3.2A)
 0.32A 3t01A-5vemA:
27.5		 3t01A-5vemA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UG8_A_IMNA2001_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		5 / 12 TRP A 117
MET A 109
TYR A 186
SER A  34
SER A 237
 None
 1.49A 3ug8A-5vemA:
undetectable		 3ug8A-5vemA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_D_ECND403_1
(FLAVOHEMOGLOBIN)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		5 / 12 ILE A 235
TYR A  53
LEU A 233
LEU A 218
ILE A 171
 None
 0.99A 4g1bD-5vemA:
undetectable		 4g1bD-5vemA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		5 / 12 ILE A 170
ALA A 137
LEU A 233
ILE A 235
PHE A 174
 None
 1.17A 4lnwA-5vemA:
undetectable		 4lnwA-5vemA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		5 / 12 ILE A 170
ALA A 137
LEU A 233
ILE A 235
PHE A 174
 None
 1.17A 4lnxA-5vemA:
undetectable		 4lnxA-5vemA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_C_SHHC406_1
(HISTONE DEACETYLASE
2)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		5 / 12 HIS A 339
HIS A 195
GLY A 194
ASP A  36
GLY A  37
 ZN  A 502 (-3.2A)
ZN  A 502 (-3.2A)
None
ZN  A 501 (-2.0A)
ZN  A 501 ( 4.9A)
 1.22A 4lxzC-5vemA:
undetectable		 4lxzC-5vemA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA301_0
(THAUMATIN-1)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		3 / 3 THR A  65
ASN A 369
SER A 370
 None
NAG  A 506 (-1.8A)
None
 0.67A 4tvtA-5vemA:
undetectable		 4tvtA-5vemA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		5 / 12 THR A  78
THR A  81
ALA A 120
ASN A  87
TYR A 307
 None
None
None
NAG  A 507 (-2.7A)
None
 1.49A 4u15A-5vemA:
undetectable		 4u15A-5vemA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		5 / 12 THR A  78
THR A  81
ALA A 120
ASN A  87
TYR A 307
 None
None
None
NAG  A 507 (-2.7A)
None
 1.44A 4u15B-5vemA:
undetectable		 4u15B-5vemA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DLV_A_5D5A930_0
(ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 2)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		5 / 12 ASP A  36
THR A  72
PRO A 122
ILE A 125
ARG A 166
 ZN  A 501 (-2.0A)
ZN  A 501 (-2.4A)
None
None
None
 0.68A 5dlvA-5vemA:
44.0		 5dlvA-5vemA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DLV_B_5D5B927_0
(ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 2)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		6 / 12 ASP A  36
THR A  72
PRO A 122
TRP A 124
ILE A 125
ARG A 166
 ZN  A 501 (-2.0A)
ZN  A 501 (-2.4A)
None
None
None
None
 0.73A 5dlvB-5vemA:
44.0		 5dlvB-5vemA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		4 / 6 LEU A  43
ARG A  39
ILE A 351
PHE A  38
 None
 0.93A 5jw1A-5vemA:
undetectable		 5jw1A-5vemA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		4 / 4 LEU A  43
ARG A  39
ILE A 351
PHE A  38
 None
 0.89A 5kirB-5vemA:
undetectable		 5kirB-5vemA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		3 / 3 THR A  81
MET A 386
HIS A 388
 None
 0.94A 5uunA-5vemA:
undetectable		 5uunA-5vemA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_1
(PROTEASE)		 5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5
(Homo
sapiens) 		5 / 12 LEU A 353
VAL A  33
ILE A 208
LEU A 185
ILE A 235
 None
 1.03A 6dgxB-5vemA:
undetectable		 6dgxB-5vemA:
11.28