SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vey'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2001_1
(SERUM ALBUMIN)		 5vey HISTONE H2B TYPE
1-J,HISTONE H2A TYPE
1-B/E
(Homo
sapiens) 		5 / 11 LEU A 140
ILE A  70
VAL A 132
GLY A 133
LEU A 123
 None
 1.33A 2bxeA-5veyA:
2.3		 2bxeA-5veyA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2001_1
(SERUM ALBUMIN)		 5vey HISTONE H2B TYPE
1-J,HISTONE H2A TYPE
1-B/E
(Homo
sapiens) 		5 / 12 LEU A 140
ILE A  70
VAL A 132
GLY A 133
LEU A 123
 None
 1.27A 2bxeB-5veyA:
undetectable		 2bxeB-5veyA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_A_NCAA300_0
(PROTOGLOBIN)		 5vey HISTONE H2B TYPE
1-J,HISTONE H2A TYPE
1-B/E
(Homo
sapiens) 		4 / 7 VAL A  20
PHE A 114
VAL A  42
ILE A  30
 None
 0.98A 3zjqA-5veyA:
undetectable		 3zjqA-5veyA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_B_NCAB300_0
(PROTOGLOBIN)		 5vey HISTONE H2B TYPE
1-J,HISTONE H2A TYPE
1-B/E
(Homo
sapiens) 		4 / 7 VAL A  20
PHE A 114
VAL A  42
ILE A  30
 None
 0.99A 3zjqB-5veyA:
undetectable		 3zjqB-5veyA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M10_A_NCAA603_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 5vey HISTONE H2B TYPE
1-J,HISTONE H2A TYPE
1-B/E
(Homo
sapiens) 		4 / 5 LEU A  78
ARG A  48
PHE A  41
LEU A 182
 None
 1.33A 5m10A-5veyA:
undetectable		 5m10A-5veyA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5vey HISTONE H2B TYPE
1-J,HISTONE H2A TYPE
1-B/E
(Homo
sapiens) 		5 / 12 ILE A 167
GLY A 156
HIS A  25
ILE A  37
ALA A  34
 None
 1.08A 5n0sA-5veyA:
undetectable		 5n0sA-5veyA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5vey HISTONE H2B TYPE
1-J,HISTONE H2A TYPE
1-B/E
(Homo
sapiens) 		6 / 12 ILE A 167
GLY A 156
HIS A  25
VAL A  24
ILE A  37
ALA A  34
 None
 1.36A 5n0tA-5veyA:
undetectable		 5n0tA-5veyA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5vey HISTONE H2B TYPE
1-J,HISTONE H2A TYPE
1-B/E
(Homo
sapiens) 		5 / 12 ILE A 167
GLY A 156
HIS A  25
ILE A  37
ALA A  34
 None
 1.02A 5n0tB-5veyA:
undetectable		 5n0tB-5veyA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5vey HISTONE H2B TYPE
1-J,HISTONE H2A TYPE
1-B/E
(Homo
sapiens) 		5 / 12 ILE A 167
GLY A 156
HIS A  25
ILE A  37
ALA A  34
 None
 1.06A 5n0wB-5veyA:
undetectable		 5n0wB-5veyA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5vey HISTONE H2B TYPE
1-J,HISTONE H2A TYPE
1-B/E
(Homo
sapiens) 		5 / 12 ILE A 167
GLY A 156
HIS A  25
ILE A  37
ALA A  34
 None
 1.05A 5n0xA-5veyA:
undetectable		 5n0xA-5veyA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5vey HISTONE H2B TYPE
1-J,HISTONE H2A TYPE
1-B/E
(Homo
sapiens) 		5 / 12 ILE A 167
GLY A 156
HIS A  25
ILE A  37
ALA A  34
 None
 1.08A 5n4iA-5veyA:
undetectable		 5n4iA-5veyA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_2
(SCRFP-TAG,GP41)		 5vey E3 UBIQUITIN-PROTEIN
LIGASE RNF169
(Homo
sapiens) 		4 / 7 GLN C 675
LEU C 672
ASP C 669
LEU C 663
 None
 1.03A 5nwvA-5veyC:
undetectable		 5nwvA-5veyC:
18.64