SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vf3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AXW_A_MTXA732_1
(THYMIDYLATE SYNTHASE)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		5 / 12 ILE A 254
GLY A 251
PHE A 252
VAL A 136
ALA A 137
 None
 1.10A 1axwA-5vf3A:
undetectable		 1axwA-5vf3A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		5 / 9 TYR A 424
ASP A 110
VAL A 307
ILE A 310
PHE A 375
 None
 1.39A 1bkfA-5vf3A:
undetectable		 1bkfA-5vf3A:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J3J_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5vf3 CAPSID VERTEX
PROTEIN GP24
(Escherichia
virus
T4) 		5 / 10 ILE a  39
ALA a  41
PHE a 271
SER a 265
ILE a 261
 None
 1.17A 1j3jA-5vf3a:
undetectable		 1j3jA-5vf3a:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KB9_A_PCFA514_0
(CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN
UBIQUINOL-CYTOCHROME
C REDUCTASE COMPLEX
CORE PROTEIN I
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		4 / 8 ILE A 340
PHE A 334
VAL A 382
SER A 388
 None
 0.99A 1kb9A-5vf3A:
undetectable
1kb9C-5vf3A:
undetectable
1kb9D-5vf3A:
undetectable
1kb9E-5vf3A:
undetectable		 1kb9A-5vf3A:
22.13
1kb9C-5vf3A:
23.67
1kb9D-5vf3A:
19.60
1kb9E-5vf3A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_A_DMEA998_1
(ACETYLCHOLINESTERASE)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		5 / 12 TYR A 189
GLY A 186
PHE A 181
TYR A 131
HIS A 145
 None
 1.20A 1maaA-5vf3A:
undetectable		 1maaA-5vf3A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_C_DMEC997_1
(ACETYLCHOLINESTERASE)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		5 / 12 TYR A 189
GLY A 186
PHE A 181
TYR A 131
HIS A 145
 None
 1.13A 1maaC-5vf3A:
undetectable		 1maaC-5vf3A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_A_FK5A301_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		5 / 9 TYR A 424
ASP A 110
VAL A 307
ILE A 310
PHE A 375
 None
 1.42A 1q6iA-5vf3A:
undetectable		 1q6iA-5vf3A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_B_FK5B401_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		5 / 10 TYR A 424
ASP A 110
VAL A 307
ILE A 310
PHE A 375
 None
 1.41A 1q6iB-5vf3A:
undetectable		 1q6iB-5vf3A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA502_1
(YKOF)		 5vf3 CAPSID VERTEX
PROTEIN GP24
(Escherichia
virus
T4) 		4 / 6 PHE a 197
ALA a 194
LEU a 198
ILE a 179
 None
 1.03A 1sbrA-5vf3a:
undetectable
1sbrB-5vf3a:
undetectable		 1sbrA-5vf3a:
18.07
1sbrB-5vf3a:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLS_A_C2FA266_0
(THYMIDYLATE SYNTHASE)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		5 / 12 ILE A 254
GLY A 251
PHE A 252
VAL A 136
ALA A 137
 None
 1.05A 1tlsA-5vf3A:
undetectable		 1tlsA-5vf3A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TSN_A_C2FA266_0
(THYMIDYLATE SYNTHASE)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		5 / 12 ILE A 254
GLY A 251
PHE A 252
VAL A 136
ALA A 137
 None
 1.09A 1tsnA-5vf3A:
undetectable		 1tsnA-5vf3A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2001_1
(SERUM ALBUMIN)		 5vf3 CAPSID VERTEX
PROTEIN GP24
(Escherichia
virus
T4) 		4 / 8 ALA a 117
PHE a 116
ALA a 131
LEU a 128
 None
 0.80A 2bxmA-5vf3a:
undetectable		 2bxmA-5vf3a:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_1
(ESTROGEN RECEPTOR)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		4 / 6 ALA A 288
ASP A 287
GLU A 289
ARG A 100
 None
 1.01A 2ouzA-5vf3A:
undetectable		 2ouzA-5vf3A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_G_CPFG1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 5vf3 HIGHLY IMMUNOGENIC
OUTER CAPSID PROTEIN
MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		3 / 3 ARG A 341
GLY A 342
SER Z 302
 None
 0.64A 2xctB-5vf3A:
undetectable		 2xctB-5vf3A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_D_SAMD603_0
(HYPOTHETICAL PROTEIN)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		5 / 12 ILE A 232
GLY A 158
GLY A 156
ALA A 233
ALA A 152
 None
 1.18A 2yvlD-5vf3A:
undetectable		 2yvlD-5vf3A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_2
(PROTEASE)		 5vf3 CAPSID VERTEX
PROTEIN GP24
(Escherichia
virus
T4) 		5 / 9 ALA a 395
VAL a 388
ILE a 163
PRO a 385
ILE a 398
 None
 1.03A 3ekvB-5vf3a:
undetectable		 3ekvB-5vf3a:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHZ_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		5 / 10 TYR A 424
ASP A 110
VAL A 307
ILE A 310
PHE A 375
 None
 1.42A 3ihzA-5vf3A:
undetectable		 3ihzA-5vf3A:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP5_B_KANB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5vf3 CAPSID VERTEX
PROTEIN GP24
(Escherichia
virus
T4) 		3 / 3 ALA a 407
ARG a 409
LYS a 393
 None
 1.01A 3kp5B-5vf3a:
undetectable		 3kp5B-5vf3a:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KZ7_A_RAPA225_1
(FK506-BINDING
PROTEIN 3)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		5 / 10 TYR A 424
ASP A 110
VAL A 307
ILE A 310
PHE A 375
 None
 1.34A 3kz7A-5vf3A:
undetectable		 3kz7A-5vf3A:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5vf3 CAPSID VERTEX
PROTEIN GP24
(Escherichia
virus
T4) 		5 / 11 ALA a 278
ALA a 274
VAL a 418
ALA a 246
GLY a 247
 None
 0.96A 3mg0K-5vf3a:
undetectable
3mg0L-5vf3a:
undetectable		 3mg0K-5vf3a:
19.47
3mg0L-5vf3a:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O5R_A_FK5A1001_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		5 / 11 TYR A 424
ASP A 110
VAL A 307
ILE A 310
PHE A 375
 None
 1.43A 3o5rA-5vf3A:
undetectable		 3o5rA-5vf3A:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SU9_A_ACTA426_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5vf3 SMALL OUTER CAPSID
PROTEIN
(Escherichia
virus
T4) 		3 / 3 GLN O  47
GLU O  27
LYS O  11
 None
 1.13A 3su9A-5vf3O:
undetectable		 3su9A-5vf3O:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQ8_A_TOPA2001_1
(DIHYDROFOLATE
REDUCTASE)		 5vf3 CAPSID VERTEX
PROTEIN GP24
(Escherichia
virus
T4) 		5 / 9 ILE a  39
ALA a  41
PHE a 271
SER a 265
ILE a 261
 None
 1.19A 3tq8A-5vf3a:
undetectable		 3tq8A-5vf3a:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_2
(CARBONIC ANHYDRASE)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		3 / 3 GLN A 183
PHE A 181
TYR A 148
 None
 0.72A 3ucjB-5vf3A:
undetectable		 3ucjB-5vf3A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_1
(CARBONIC ANHYDRASE)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		3 / 3 GLN A 183
PHE A 181
TYR A 148
 None
 0.74A 3ucjA-5vf3A:
undetectable		 3ucjA-5vf3A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UF8_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		5 / 10 TYR A 424
ASP A 110
VAL A 307
ILE A 310
PHE A 375
 None
 1.40A 3uf8A-5vf3A:
undetectable		 3uf8A-5vf3A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQA_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		5 / 10 TYR A 424
ASP A 110
VAL A 307
ILE A 310
PHE A 375
 None
 1.42A 3uqaA-5vf3A:
undetectable		 3uqaA-5vf3A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAW_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN
SMT3,PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		5 / 11 TYR A 424
ASP A 110
VAL A 307
ILE A 310
PHE A 375
 None
 1.40A 3vawA-5vf3A:
undetectable		 3vawA-5vf3A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		4 / 8 PHE A 434
VAL A 382
ILE A 521
GLU A 360
 None
 1.08A 4a97C-5vf3A:
undetectable		 4a97C-5vf3A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		4 / 8 PHE A 434
VAL A 382
ILE A 521
GLU A 360
 None
 1.08A 4a97G-5vf3A:
undetectable		 4a97G-5vf3A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BB2_B_STRB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5vf3 CAPSID VERTEX
PROTEIN GP24
(Escherichia
virus
T4) 		5 / 11 ALA a 274
SER a 275
THR a 270
ILE a  39
SER a 339
 None
 1.27A 4bb2A-5vf3a:
undetectable
4bb2B-5vf3a:
undetectable		 4bb2A-5vf3a:
23.13
4bb2B-5vf3a:
7.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_1
(ASPARTYL PROTEASE)		 5vf3 CAPSID VERTEX
PROTEIN GP24
(Escherichia
virus
T4) 		5 / 10 ALA a 395
VAL a 388
ILE a 163
PRO a 385
ILE a 398
 None
 1.06A 4dqcA-5vf3a:
undetectable		 4dqcA-5vf3a:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRH_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		5 / 12 TYR A 424
ASP A 110
VAL A 307
ILE A 310
PHE A 375
 None
 1.33A 4drhA-5vf3A:
undetectable		 4drhA-5vf3A:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ2_A_FK5A200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		5 / 11 TYR A 424
ASP A 110
VAL A 307
ILE A 310
PHE A 375
 None
 1.40A 4dz2A-5vf3A:
undetectable
4dz2B-5vf3A:
undetectable		 4dz2A-5vf3A:
12.90
4dz2B-5vf3A:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ2_B_FK5B200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		5 / 11 TYR A 424
ASP A 110
VAL A 307
ILE A 310
PHE A 375
 None
 1.40A 4dz2A-5vf3A:
undetectable
4dz2B-5vf3A:
undetectable		 4dz2A-5vf3A:
12.90
4dz2B-5vf3A:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ3_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		5 / 10 TYR A 424
ASP A 110
VAL A 307
ILE A 310
PHE A 375
 None
 1.42A 4dz3A-5vf3A:
undetectable		 4dz3A-5vf3A:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ3_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		5 / 10 TYR A 424
ASP A 110
VAL A 307
ILE A 310
PHE A 375
 None
 1.42A 4dz3B-5vf3A:
undetectable		 4dz3B-5vf3A:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_D_D16D301_1
(THYMIDYLATE SYNTHASE)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		5 / 12 ILE A 254
GLY A 251
PHE A 252
VAL A 136
ALA A 137
 None
 1.10A 4foxD-5vf3A:
undetectable		 4foxD-5vf3A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FQS_A_LYAA302_1
(THYMIDYLATE SYNTHASE)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		5 / 12 ILE A 254
GLY A 251
PHE A 252
VAL A 136
ALA A 137
 None
 1.14A 4fqsA-5vf3A:
undetectable		 4fqsA-5vf3A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FQS_B_LYAB302_1
(THYMIDYLATE SYNTHASE)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		5 / 12 ILE A 254
GLY A 251
PHE A 252
VAL A 136
ALA A 137
 None
 1.14A 4fqsB-5vf3A:
undetectable		 4fqsB-5vf3A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA501_1
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 5vf3 CAPSID VERTEX
PROTEIN GP24
(Escherichia
virus
T4) 		5 / 12 ILE a 210
ASP a 213
THR a 220
VAL a 221
ILE a 340
 None
 1.22A 4i41A-5vf3a:
undetectable		 4i41A-5vf3a:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAX_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		5 / 10 TYR A 424
ASP A 110
VAL A 307
ILE A 310
PHE A 375
 None
 1.44A 4laxA-5vf3A:
undetectable		 4laxA-5vf3A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1W_A_017A104_2
(ASPARTYL PROTEASE)		 5vf3 CAPSID VERTEX
PROTEIN GP24
(Escherichia
virus
T4) 		5 / 10 ALA a 395
VAL a 388
ILE a 163
PRO a 385
ILE a 398
 None
 1.08A 4q1wB-5vf3a:
undetectable		 4q1wB-5vf3a:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QT2_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		5 / 10 TYR A 424
ASP A 110
VAL A 307
ILE A 310
PHE A 375
 None
 1.40A 4qt2A-5vf3A:
undetectable		 4qt2A-5vf3A:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QT3_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		5 / 10 TYR A 424
ASP A 110
VAL A 307
ILE A 310
PHE A 375
 None
 1.37A 4qt3A-5vf3A:
undetectable		 4qt3A-5vf3A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_LZUA3008_1
(ALDEHYDE OXIDASE)		 5vf3 CAPSID VERTEX
PROTEIN GP24
(Escherichia
virus
T4) 		4 / 8 GLU a 199
ASP a 200
ARG a  29
PRO a 195
 None
 1.14A 4uhxA-5vf3a:
undetectable		 4uhxA-5vf3a:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_RTZA3009_1
(ALDEHYDE OXIDASE)		 5vf3 CAPSID VERTEX
PROTEIN GP24
(Escherichia
virus
T4) 		4 / 8 GLU a 199
ASP a 200
ARG a  29
PRO a 195
 None
 1.14A 4uhxA-5vf3a:
undetectable		 4uhxA-5vf3a:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UY8_7_TRP71002_0
(TRYPTOPHANASE)		 5vf3 CAPSID VERTEX
PROTEIN GP24
(Escherichia
virus
T4) 		4 / 4 ILE a 210
ASN a 211
ILE a  39
VAL a  40
 None
 1.00A 4uy87-5vf3a:
undetectable		 4uy87-5vf3a:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_A_QI9A602_0
(CYTOCHROME P450 2D6)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		5 / 9 PHE A 404
SER A 388
THR A 391
VAL A 423
LEU A 354
 None
 1.15A 4wnvA-5vf3A:
undetectable		 4wnvA-5vf3A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_B_QI9B602_0
(CYTOCHROME P450 2D6)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		5 / 9 PHE A 404
SER A 388
THR A 391
VAL A 423
PHE A 434
 None
 1.50A 4wnvB-5vf3A:
undetectable		 4wnvB-5vf3A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_D_QI9D602_0
(CYTOCHROME P450 2D6)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		5 / 7 PHE A 404
SER A 388
THR A 391
VAL A 423
PHE A 434
 None
 1.46A 4wnvD-5vf3A:
undetectable		 4wnvD-5vf3A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		4 / 6 PHE A 125
LYS A 256
ASN A 482
PRO A 483
 None
 1.05A 4yv5B-5vf3A:
undetectable		 4yv5B-5vf3A:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		4 / 6 PHE A 125
LYS A 256
ASN A 482
PRO A 483
 None
 1.06A 4yv5A-5vf3A:
undetectable		 4yv5A-5vf3A:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_1
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		3 / 3 ARG A 304
ASN A 311
ASP A 432
 None
 0.88A 5gwxA-5vf3A:
undetectable		 5gwxA-5vf3A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HUA_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		5 / 11 TYR A 424
ASP A 110
VAL A 307
ILE A 310
PHE A 375
 None
 1.43A 5huaA-5vf3A:
undetectable		 5huaA-5vf3A:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWC_A_FK5A201_1
(FK506-BINDING
PROTEIN 1A)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		5 / 11 TYR A 424
ASP A 110
VAL A 307
ILE A 310
PHE A 375
 None
 1.40A 5hwcA-5vf3A:
undetectable		 5hwcA-5vf3A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_1
(METHYLTRANSFERASE)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		4 / 7 PHE A 434
ILE A 425
ASP A 432
ASN A 384
 None
 1.00A 5n5dA-5vf3A:
undetectable		 5n5dA-5vf3A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_C_SAMC201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		5 / 12 ILE A 340
ILE A 521
GLY A 520
LEU A 353
VAL A 385
 None
 1.17A 5twjC-5vf3A:
undetectable		 5twjC-5vf3A:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5vf3 CAPSID VERTEX
PROTEIN GP24
(Escherichia
virus
T4) 		3 / 3 TYR a 342
ALA a 207
TYR a  36
 None
 0.86A 5uunB-5vf3a:
undetectable		 5uunB-5vf3a:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7B_B_PA1B204_1
(ACYLOXYACYL
HYDROLASE SMALL
SUBUNIT
ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT)		 5vf3 CAPSID VERTEX
PROTEIN GP24
(Escherichia
virus
T4) 		3 / 3 GLY a 191
ASN a 190
ARG a  21
 None
 0.68A 5w7bD-5vf3a:
undetectable		 5w7bD-5vf3a:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_B_SAMB301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		5 / 12 TYR A 421
GLY A 373
ILE A 377
TYR A 433
GLY A 437
 None
 0.94A 5wyqB-5vf3A:
undetectable		 5wyqB-5vf3A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		4 / 6 TYR A 433
GLN A 427
VAL A 412
ALA A 314
 None
 1.25A 6djzB-5vf3A:
undetectable		 6djzB-5vf3A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_1
(PEPTIDYLPROLYL
ISOMERASE)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		5 / 10 TYR A 424
ASP A 110
VAL A 307
ILE A 310
PHE A 375
 None
 1.39A 6mkeC-5vf3A:
undetectable		 6mkeC-5vf3A:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_1
(PEPTIDYLPROLYL
ISOMERASE)		 5vf3 MAJOR CAPSID PROTEIN
(Escherichia
virus
T4) 		5 / 10 TYR A 424
ASP A 110
VAL A 307
ILE A 310
PHE A 375
 None
 1.41A 6mkeD-5vf3A:
undetectable		 6mkeD-5vf3A:
11.81