SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vfd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		 5vfd BETA-LACTAMASE
(Acinetobacter
baumannii) 		7 / 12 ALA A  80
SER A  81
SER A 128
LYS A 218
SER A 219
GLY A 220
ARG A 261
 9CP  A 306 (-3.3A)
9CP  A 306 (-1.4A)
9CP  A 306 (-2.8A)
9CP  A 306 (-3.0A)
9CP  A 306 (-2.9A)
9CP  A 306 (-3.5A)
9CP  A 306 (-2.7A)
 0.63A 1ghmA-5vfdA:
17.8		 1ghmA-5vfdA:
24.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EFJ_A_37TA502_1
(3,7-DIMETHYLXANTHINE
METHYLTRANSFERASE)		 5vfd BETA-LACTAMASE
(Acinetobacter
baumannii) 		5 / 12 TYR A  45
ILE A 274
ILE A  57
ILE A  42
TYR A  66
 None
 1.34A 2efjA-5vfdA:
undetectable		 2efjA-5vfdA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_C_CHDC1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5vfd BETA-LACTAMASE
(Acinetobacter
baumannii) 		4 / 5 PHE A 182
PHE A 154
LEU A 172
PHE A 166
 None
 1.35A 2y69C-5vfdA:
undetectable
2y69J-5vfdA:
undetectable		 2y69C-5vfdA:
18.37
2y69J-5vfdA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5vfd BETA-LACTAMASE
(Acinetobacter
baumannii) 		4 / 5 PHE A 182
PHE A 154
LEU A 172
PHE A 166
 None
 1.32A 3abmC-5vfdA:
undetectable
3abmJ-5vfdA:
undetectable		 3abmC-5vfdA:
18.37
3abmJ-5vfdA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5vfd BETA-LACTAMASE
(Acinetobacter
baumannii) 		4 / 5 PHE A 182
PHE A 154
LEU A 172
PHE A 166
 None
 1.38A 3abmP-5vfdA:
undetectable
3abmW-5vfdA:
undetectable		 3abmP-5vfdA:
18.37
3abmW-5vfdA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5vfd BETA-LACTAMASE
(Acinetobacter
baumannii) 		4 / 5 PHE A 182
PHE A 154
LEU A 172
PHE A 166
 None
 1.34A 3ag3C-5vfdA:
undetectable
3ag3J-5vfdA:
undetectable		 3ag3C-5vfdA:
18.37
3ag3J-5vfdA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_A_SAMA220_0
(16S RRNA METHYLASE)		 5vfd BETA-LACTAMASE
(Acinetobacter
baumannii) 		5 / 12 GLY A 122
VAL A 201
ALA A 217
LEU A 127
THR A  82
 None
None
None
9CM  A 307 (-3.9A)
None
 1.14A 3mteA-5vfdA:
undetectable		 3mteA-5vfdA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA308_1
(BETA-LACTAMASE)		 5vfd BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 12 SER A  81
SER A 128
ARG A 261
LYS A 218
GLY A 220
GLY A 222
 9CP  A 306 (-1.4A)
9CP  A 306 (-2.8A)
9CP  A 306 (-2.7A)
9CP  A 306 (-3.0A)
9CP  A 306 (-3.5A)
9CP  A 306 ( 4.4A)
 0.94A 3ny4A-5vfdA:
18.9		 3ny4A-5vfdA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		 5vfd BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 12 ALA A  80
SER A  81
SER A 128
LYS A 218
GLY A 220
ARG A 261
 9CP  A 306 (-3.3A)
9CP  A 306 (-1.4A)
9CP  A 306 (-2.8A)
9CP  A 306 (-3.0A)
9CP  A 306 (-3.5A)
9CP  A 306 (-2.7A)
 0.59A 3sh8A-5vfdA:
19.2		 3sh8A-5vfdA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		 5vfd BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 12 ALA A  80
SER A  81
SER A 128
LYS A 218
GLY A 220
ARG A 261
 9CP  A 306 (-3.3A)
9CP  A 306 (-1.4A)
9CP  A 306 (-2.8A)
9CP  A 306 (-3.0A)
9CP  A 306 (-3.5A)
9CP  A 306 (-2.7A)
 0.58A 3sh8B-5vfdA:
19.3		 3sh8B-5vfdA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AT0_A_ACTA1490_0
(3-KETOSTEROID-DELTA4
-5ALPHA-DEHYDROGENAS
E)		 5vfd BETA-LACTAMASE
(Acinetobacter
baumannii) 		3 / 3 GLU A  39
TYR A  66
SER A  64
 None
 0.99A 4at0A-5vfdA:
undetectable		 4at0A-5vfdA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1Y_A_RBFA1176_1
(PUTATIVE PROTEASE I)		 5vfd BETA-LACTAMASE
(Acinetobacter
baumannii) 		4 / 8 GLN A 178
LYS A 150
ASN A 156
THR A 157
 None
 1.31A 4d1yA-5vfdA:
undetectable
4d1yB-5vfdA:
undetectable		 4d1yA-5vfdA:
22.18
4d1yB-5vfdA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		 5vfd BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 12 ALA A  80
SER A  81
SER A 128
LYS A 218
GLY A 220
ARG A 261
 9CP  A 306 (-3.3A)
9CP  A 306 (-1.4A)
9CP  A 306 (-2.8A)
9CP  A 306 (-3.0A)
9CP  A 306 (-3.5A)
9CP  A 306 (-2.7A)
 0.61A 4n9kA-5vfdA:
19.1		 4n9kA-5vfdA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		 5vfd BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 12 ALA A  80
SER A  81
SER A 128
LYS A 218
GLY A 220
ARG A 261
 9CP  A 306 (-3.3A)
9CP  A 306 (-1.4A)
9CP  A 306 (-2.8A)
9CP  A 306 (-3.0A)
9CP  A 306 (-3.5A)
9CP  A 306 (-2.7A)
 0.58A 4n9kB-5vfdA:
19.2		 4n9kB-5vfdA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_0
(PROLINE--TRNA LIGASE)		 5vfd BETA-LACTAMASE
(Acinetobacter
baumannii) 		5 / 12 LEU A 168
VAL A 130
THR A  82
SER A 247
GLY A 234
 9CP  A 306 ( 4.6A)
KCX  A  84 (-3.8A)
None
None
None
 1.06A 4q15A-5vfdA:
undetectable		 4q15A-5vfdA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		 5vfd BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 12 ALA A  80
SER A  81
SER A 128
LYS A 218
GLY A 220
ARG A 261
 9CP  A 306 (-3.3A)
9CP  A 306 (-1.4A)
9CP  A 306 (-2.8A)
9CP  A 306 (-3.0A)
9CP  A 306 (-3.5A)
9CP  A 306 (-2.7A)
 0.59A 5ghyA-5vfdA:
19.3		 5ghyA-5vfdA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		 5vfd BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 12 ALA A  80
SER A  81
SER A 128
LYS A 218
GLY A 220
ARG A 261
 9CP  A 306 (-3.3A)
9CP  A 306 (-1.4A)
9CP  A 306 (-2.8A)
9CP  A 306 (-3.0A)
9CP  A 306 (-3.5A)
9CP  A 306 (-2.7A)
 0.58A 5ghyB-5vfdA:
19.3		 5ghyB-5vfdA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		 5vfd BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 11 ALA A  80
SER A  81
SER A 128
LYS A 218
GLY A 220
ARG A 261
 9CP  A 306 (-3.3A)
9CP  A 306 (-1.4A)
9CP  A 306 (-2.8A)
9CP  A 306 (-3.0A)
9CP  A 306 (-3.5A)
9CP  A 306 (-2.7A)
 0.58A 5ghzA-5vfdA:
19.1		 5ghzA-5vfdA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		 5vfd BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 10 ALA A  80
SER A  81
SER A 128
LYS A 218
GLY A 220
ARG A 261
 9CP  A 306 (-3.3A)
9CP  A 306 (-1.4A)
9CP  A 306 (-2.8A)
9CP  A 306 (-3.0A)
9CP  A 306 (-3.5A)
9CP  A 306 (-2.7A)
 0.60A 5ghzB-5vfdA:
19.1		 5ghzB-5vfdA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMF_A_6U9A1301_1
(ION TRANSPORT
PROTEIN)		 5vfd BETA-LACTAMASE
(Acinetobacter
baumannii) 		4 / 6 THR A 120
GLY A 122
GLU A 123
ILE A 207
 None
 0.57A 5kmfA-5vfdA:
undetectable
5kmfC-5vfdA:
undetectable		 5kmfA-5vfdA:
21.21
5kmfC-5vfdA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5vfd BETA-LACTAMASE
(Acinetobacter
baumannii) 		4 / 5 PHE A 182
PHE A 154
LEU A 172
PHE A 166
 None
 1.30A 5wauC-5vfdA:
undetectable
5wauJ-5vfdA:
undetectable		 5wauC-5vfdA:
18.37
5wauJ-5vfdA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5vfd BETA-LACTAMASE
(Acinetobacter
baumannii) 		4 / 5 PHE A 182
PHE A 154
LEU A 172
PHE A 166
 None
 1.32A 5wauc-5vfdA:
undetectable
5wauj-5vfdA:
undetectable		 5wauc-5vfdA:
18.37
5wauj-5vfdA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5vfd BETA-LACTAMASE
(Acinetobacter
baumannii) 		4 / 5 PHE A 182
PHE A 154
LEU A 172
PHE A 166
 None
 1.33A 5xdqC-5vfdA:
undetectable
5xdqJ-5vfdA:
undetectable		 5xdqC-5vfdA:
18.37
5xdqJ-5vfdA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5vfd BETA-LACTAMASE
(Acinetobacter
baumannii) 		4 / 5 PHE A 182
PHE A 154
LEU A 172
PHE A 166
 None
 1.33A 5xdqP-5vfdA:
undetectable
5xdqW-5vfdA:
undetectable		 5xdqP-5vfdA:
18.37
5xdqW-5vfdA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		 5vfd BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 12 SER A  81
SER A 128
ARG A 261
LYS A 218
GLY A 220
GLY A 222
 9CP  A 306 (-1.4A)
9CP  A 306 (-2.8A)
9CP  A 306 (-2.7A)
9CP  A 306 (-3.0A)
9CP  A 306 (-3.5A)
9CP  A 306 ( 4.4A)
 0.92A 6b5yB-5vfdA:
19.0		 6b5yB-5vfdA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		 5vfd BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 12 SER A  81
SER A 128
ARG A 261
LYS A 218
GLY A 220
GLY A 222
 9CP  A 306 (-1.4A)
9CP  A 306 (-2.8A)
9CP  A 306 (-2.7A)
9CP  A 306 (-3.0A)
9CP  A 306 (-3.5A)
9CP  A 306 ( 4.4A)
 0.89A 6b68D-5vfdA:
18.9		 6b68D-5vfdA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		 5vfd BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 12 SER A  81
SER A 128
ARG A 261
LYS A 218
GLY A 220
GLY A 222
 9CP  A 306 (-1.4A)
9CP  A 306 (-2.8A)
9CP  A 306 (-2.7A)
9CP  A 306 (-3.0A)
9CP  A 306 (-3.5A)
9CP  A 306 ( 4.4A)
 0.85A 6b69D-5vfdA:
18.9		 6b69D-5vfdA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		 5vfd BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 12 SER A  81
SER A 128
ARG A 261
LYS A 218
GLY A 220
GLY A 222
 9CP  A 306 (-1.4A)
9CP  A 306 (-2.8A)
9CP  A 306 (-2.7A)
9CP  A 306 (-3.0A)
9CP  A 306 (-3.5A)
9CP  A 306 ( 4.4A)
 0.86A 6b6aB-5vfdA:
19.0		 6b6aB-5vfdA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		 5vfd BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 12 SER A  81
SER A 128
ARG A 261
LYS A 218
GLY A 220
GLY A 222
 9CP  A 306 (-1.4A)
9CP  A 306 (-2.8A)
9CP  A 306 (-2.7A)
9CP  A 306 (-3.0A)
9CP  A 306 (-3.5A)
9CP  A 306 ( 4.4A)
 0.84A 6b6aD-5vfdA:
18.9		 6b6aD-5vfdA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		 5vfd BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 12 SER A  81
SER A 128
ARG A 261
LYS A 218
GLY A 220
GLY A 222
 9CP  A 306 (-1.4A)
9CP  A 306 (-2.8A)
9CP  A 306 (-2.7A)
9CP  A 306 (-3.0A)
9CP  A 306 (-3.5A)
9CP  A 306 ( 4.4A)
 0.90A 6b6cA-5vfdA:
19.0		 6b6cA-5vfdA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		 5vfd BETA-LACTAMASE
(Acinetobacter
baumannii) 		6 / 12 SER A  81
SER A 128
ARG A 261
LYS A 218
GLY A 220
GLY A 222
 9CP  A 306 (-1.4A)
9CP  A 306 (-2.8A)
9CP  A 306 (-2.7A)
9CP  A 306 (-3.0A)
9CP  A 306 (-3.5A)
9CP  A 306 ( 4.4A)
 0.86A 6b6eA-5vfdA:
19.0		 6b6eA-5vfdA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_1
(RIFAMPIN
MONOOXYGENASE)		 5vfd BETA-LACTAMASE
(Acinetobacter
baumannii) 		5 / 12 PHE A 182
GLY A 230
VAL A 229
THR A 175
GLY A 155
 None
 1.18A 6brdB-5vfdA:
undetectable		 6brdB-5vfdA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA813_0
(GEPHYRIN)		 5vfd BETA-LACTAMASE
(Acinetobacter
baumannii) 		3 / 3 THR A  65
ALA A  73
LYS A  75
 None
 0.70A 6fgcA-5vfdA:
undetectable		 6fgcA-5vfdA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA817_0
(GEPHYRIN)		 5vfd BETA-LACTAMASE
(Acinetobacter
baumannii) 		3 / 3 THR A  65
ALA A  73
LYS A  75
 None
 0.70A 6fgdA-5vfdA:
undetectable		 6fgdA-5vfdA:
19.81