SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vfk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 5vfk UNCHARACTERIZED
PROTEIN
(Sulfolobus
solfataricus) 		3 / 3 GLY A   9
GLU A   7
ASP A  12
 None
 0.63A 2b25B-5vfkA:
undetectable		 2b25B-5vfkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 5vfk UNCHARACTERIZED
PROTEIN
(Sulfolobus
solfataricus) 		4 / 5 LEU A 111
ALA A  90
SER A  92
LYS A 110
 None
 1.05A 2othA-5vfkA:
undetectable		 2othA-5vfkA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CO4_A_GCSA401_1
(CHITINASE)		 5vfk UNCHARACTERIZED
PROTEIN
(Sulfolobus
solfataricus) 		3 / 3 GLU A 134
HIS A 144
HIS A 145
 None
 0.80A 3co4A-5vfkA:
undetectable		 3co4A-5vfkA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_F_H3PF552_1
(GLUTAMATE
DEHYDROGENASE)		 5vfk UNCHARACTERIZED
PROTEIN
(Sulfolobus
solfataricus) 		4 / 7 ILE A  24
LYS A  31
ILE A  44
TYR A 115
 None
 1.14A 3eteD-5vfkA:
undetectable
3eteF-5vfkA:
undetectable		 3eteD-5vfkA:
8.79
3eteF-5vfkA:
8.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1F_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 5vfk UNCHARACTERIZED
PROTEIN
(Sulfolobus
solfataricus) 		5 / 12 LEU A 111
LEU A  95
HIS A 145
LEU A 104
ILE A 103
 None
 0.98A 4x1fA-5vfkA:
undetectable		 4x1fA-5vfkA:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1G_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 5vfk UNCHARACTERIZED
PROTEIN
(Sulfolobus
solfataricus) 		5 / 12 LEU A 111
LEU A  95
HIS A 145
LEU A 104
ILE A 103
 None
 0.99A 4x1gA-5vfkA:
undetectable		 4x1gA-5vfkA:
13.83