SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vfz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3003_1
(SERUM ALBUMIN)		 5vfz GP33
(Mycobacterium
virus
Brujita) 		3 / 4 LYS A 137
ALA A 141
MET A 196
 None
 0.98A 1hk3A-5vfzA:
2.3		 1hk3A-5vfzA:
7.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5vfz GP33
(Mycobacterium
virus
Brujita) 		4 / 6 ILE A 313
GLY A 241
ALA A 243
HIS A 238
 None
 1.00A 1wpuA-5vfzA:
undetectable		 1wpuA-5vfzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5vfz GP33
(Mycobacterium
virus
Brujita) 		4 / 6 ILE A 313
GLY A 241
ALA A 243
HIS A 238
 None
 1.00A 1wpuB-5vfzA:
2.3		 1wpuB-5vfzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_D_CHDD702_0
(FERROCHELATASE)		 5vfz GP33
(Mycobacterium
virus
Brujita) 		3 / 3 ARG A 138
GLY A 205
PRO A 206
 None
 0.63A 2hreD-5vfzA:
undetectable		 2hreD-5vfzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_1
(ANDROGEN RECEPTOR)		 5vfz GP33
(Mycobacterium
virus
Brujita) 		5 / 12 LEU A 257
GLY A 150
GLN A 149
ALA A 243
LEU A 245
 None
 1.17A 2oz7A-5vfzA:
undetectable		 2oz7A-5vfzA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0I_A_BEZA990_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 5vfz GP33
(Mycobacterium
virus
Brujita) 		4 / 8 LEU A 251
SER A 262
LEU A 263
HIS A 260
 None
 1.11A 2q0iA-5vfzA:
undetectable		 2q0iA-5vfzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_2
(PHOSPHOLIPASE A2)		 5vfz GP33
(Mycobacterium
virus
Brujita) 		4 / 6 GLN A 275
GLY A 280
ARG A 277
LEU A 257
 None
 1.04A 3bjwE-5vfzA:
undetectable		 3bjwE-5vfzA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_A_ADNA438_1
(ADENOSYLHOMOCYSTEINA
SE)		 5vfz GP33
(Mycobacterium
virus
Brujita) 		5 / 12 LEU A 145
LEU A 166
LEU A 164
GLY A 161
PHE A 203
 None
 1.31A 3g1uA-5vfzA:
undetectable		 3g1uA-5vfzA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_1
(ADENOSYLHOMOCYSTEINA
SE)		 5vfz GP33
(Mycobacterium
virus
Brujita) 		5 / 12 LEU A 145
LEU A 166
LEU A 164
GLY A 161
PHE A 203
 None
 1.32A 3g1uB-5vfzA:
undetectable		 3g1uB-5vfzA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_1
(ADENOSYLHOMOCYSTEINA
SE)		 5vfz GP33
(Mycobacterium
virus
Brujita) 		5 / 12 LEU A 145
LEU A 166
LEU A 164
GLY A 161
PHE A 203
 None
 1.31A 3g1uC-5vfzA:
undetectable		 3g1uC-5vfzA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_1
(ADENOSYLHOMOCYSTEINA
SE)		 5vfz GP33
(Mycobacterium
virus
Brujita) 		5 / 12 LEU A 145
LEU A 166
LEU A 164
GLY A 161
PHE A 203
 None
 1.30A 3glqA-5vfzA:
undetectable		 3glqA-5vfzA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_1
(ADENOSYLHOMOCYSTEINA
SE)		 5vfz GP33
(Mycobacterium
virus
Brujita) 		5 / 12 LEU A 145
LEU A 166
LEU A 164
GLY A 161
PHE A 203
 None
 1.29A 3glqB-5vfzA:
undetectable		 3glqB-5vfzA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5vfz GP33
(Mycobacterium
virus
Brujita) 		5 / 12 LEU A 145
LEU A 166
LEU A 164
GLY A 161
PHE A 203
 None
 1.28A 3n58A-5vfzA:
undetectable		 3n58A-5vfzA:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5vfz GP33
(Mycobacterium
virus
Brujita) 		5 / 12 VAL A  23
ALA A  52
TRP A  69
LEU A  93
PHE A  92
 None
GOL  A 401 (-3.6A)
None
NA  A 402 ( 4.8A)
None
 1.39A 4iaqA-5vfzA:
undetectable		 4iaqA-5vfzA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_RTZA3009_1
(ALDEHYDE OXIDASE)		 5vfz GP33
(Mycobacterium
virus
Brujita) 		4 / 8 HIS A 210
SER A 215
ARG A 212
ARG A 213
 None
 1.20A 4uhxA-5vfzA:
undetectable		 4uhxA-5vfzA:
5.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WCX_C_SAMC503_0
(BIOTIN AND THIAMIN
SYNTHESIS ASSOCIATED)		 5vfz GP33
(Mycobacterium
virus
Brujita) 		5 / 12 GLU A 214
GLY A 218
GLU A 222
PRO A 206
HIS A 210
 None
 1.18A 4wcxC-5vfzA:
undetectable		 4wcxC-5vfzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5vfz GP33
(Mycobacterium
virus
Brujita) 		4 / 5 ARG A 169
MET A 171
THR A 170
LEU A 183
 None
 1.36A 5z86J-5vfzA:
undetectable		 5z86J-5vfzA:
undetectable