SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vg2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_A_DEXA1999_1
(GLUCOCORTICOID
RECEPTOR)		 5vg2 INTRADIOL
RING-CLEAVAGE
DIOXYGENASE
(Tetranychus
urticae) 		5 / 12 LEU U  91
ASN U  92
LEU U  93
GLY U 151
ILE U 243
 None
 1.23A 1p93A-5vg2U:
undetectable		 1p93A-5vg2U:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9A_A_BEZA306_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 5vg2 INTRADIOL
RING-CLEAVAGE
DIOXYGENASE
(Tetranychus
urticae) 		7 / 11 GLY U  65
PRO U  66
TYR U 118
TYR U 163
ARG U 166
HIS U 169
HIS U 171
 None
None
FE  U 301 (-4.3A)
FE  U 301 (-4.8A)
FE  U 301 ( 4.9A)
FE  U 301 (-3.5A)
FE  U 301 (-3.3A)
 0.46A 1s9aA-5vg2U:
17.1		 1s9aA-5vg2U:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9A_B_BEZB307_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 5vg2 INTRADIOL
RING-CLEAVAGE
DIOXYGENASE
(Tetranychus
urticae) 		8 / 12 GLY U  65
PRO U  66
TYR U 118
TYR U 163
ARG U 166
HIS U 169
HIS U 171
GLN U 185
 None
None
FE  U 301 (-4.3A)
FE  U 301 (-4.8A)
FE  U 301 ( 4.9A)
FE  U 301 (-3.5A)
FE  U 301 (-3.3A)
None
 0.49A 1s9aB-5vg2U:
19.0		 1s9aB-5vg2U:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9A_B_BEZB307_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 5vg2 INTRADIOL
RING-CLEAVAGE
DIOXYGENASE
(Tetranychus
urticae) 		5 / 12 GLY U  65
PRO U  66
TYR U 163
HIS U 169
GLN U 185
 None
None
FE  U 301 (-4.8A)
FE  U 301 (-3.5A)
None
 1.50A 1s9aB-5vg2U:
19.0		 1s9aB-5vg2U:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_A_BEZA881_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 5vg2 INTRADIOL
RING-CLEAVAGE
DIOXYGENASE
(Tetranychus
urticae) 		7 / 11 GLY U  65
PRO U  66
TYR U 118
TYR U 163
ARG U 166
HIS U 169
HIS U 171
 None
None
FE  U 301 (-4.3A)
FE  U 301 (-4.8A)
FE  U 301 ( 4.9A)
FE  U 301 (-3.5A)
FE  U 301 (-3.3A)
 0.40A 1tmxA-5vg2U:
16.6		 1tmxA-5vg2U:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_B_BEZB882_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 5vg2 INTRADIOL
RING-CLEAVAGE
DIOXYGENASE
(Tetranychus
urticae) 		7 / 12 GLY U  65
PRO U  66
TYR U 118
TYR U 163
ARG U 166
HIS U 169
HIS U 171
 None
None
FE  U 301 (-4.3A)
FE  U 301 (-4.8A)
FE  U 301 ( 4.9A)
FE  U 301 (-3.5A)
FE  U 301 (-3.3A)
 0.35A 1tmxB-5vg2U:
17.4		 1tmxB-5vg2U:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_B_BEZB882_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 5vg2 INTRADIOL
RING-CLEAVAGE
DIOXYGENASE
(Tetranychus
urticae) 		5 / 12 GLY U  65
TYR U 163
ARG U 166
HIS U 169
HIS U 171
 None
FE  U 301 (-4.8A)
FE  U 301 ( 4.9A)
FE  U 301 (-3.5A)
FE  U 301 (-3.3A)
 1.40A 1tmxB-5vg2U:
17.4		 1tmxB-5vg2U:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_1
(GLUCOCORTICOID
RECEPTOR)		 5vg2 INTRADIOL
RING-CLEAVAGE
DIOXYGENASE
(Tetranychus
urticae) 		5 / 12 LEU U 256
GLY U 184
GLN U 185
ARG U 166
PHE U 221
 None
None
None
FE  U 301 ( 4.9A)
None
 1.48A 3h52C-5vg2U:
undetectable		 3h52C-5vg2U:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGI_A_BEZA284_0
(CATECHOL
1,2-DIOXYGENASE)		 5vg2 INTRADIOL
RING-CLEAVAGE
DIOXYGENASE
(Tetranychus
urticae) 		8 / 12 GLY U  65
PRO U  66
TYR U  67
TYR U 118
TYR U 163
ARG U 166
HIS U 169
HIS U 171
 None
None
None
FE  U 301 (-4.3A)
FE  U 301 (-4.8A)
FE  U 301 ( 4.9A)
FE  U 301 (-3.5A)
FE  U 301 (-3.3A)
 0.44A 3hgiA-5vg2U:
17.9		 3hgiA-5vg2U:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G5J_A_0WMA1102_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 5vg2 INTRADIOL
RING-CLEAVAGE
DIOXYGENASE
(Tetranychus
urticae) 		4 / 7 PHE U 159
ILE U 109
PRO U 160
HIS U 169
 None
None
None
FE  U 301 (-3.5A)
 1.07A 4g5jA-5vg2U:
undetectable		 4g5jA-5vg2U:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QKN_A_JMSA602_1
(ALPHA-KETOGLUTARATE-
DEPENDENT
DIOXYGENASE FTO)		 5vg2 INTRADIOL
RING-CLEAVAGE
DIOXYGENASE
(Tetranychus
urticae) 		4 / 8 LEU U 158
PRO U 201
SER U 115
HIS U 162
 None
 1.18A 4qknA-5vg2U:
undetectable		 4qknA-5vg2U:
9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 5vg2 INTRADIOL
RING-CLEAVAGE
DIOXYGENASE
(Tetranychus
urticae) 		5 / 12 ILE U  74
THR U 144
GLN U 145
GLU U 156
GLU U  80
 None
 1.37A 6bzoC-5vg2U:
undetectable		 6bzoC-5vg2U:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_B_SAMB301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 5vg2 INTRADIOL
RING-CLEAVAGE
DIOXYGENASE
(Tetranychus
urticae) 		5 / 12 LEU U 244
ILE U 228
GLY U 242
VAL U 107
ILE U 186
 None
 0.88A 6emuB-5vg2U:
undetectable		 6emuB-5vg2U:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_C_SAMC301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 5vg2 INTRADIOL
RING-CLEAVAGE
DIOXYGENASE
(Tetranychus
urticae) 		5 / 12 LEU U 244
ILE U 228
GLY U 242
VAL U 107
ILE U 186
 None
 0.95A 6emuC-5vg2U:
undetectable		 6emuC-5vg2U:
undetectable