SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vg9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_B_AG2B7001_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 5vg9 PROTEIN-S-ISOPRENYLC
YSTEINE
O-METHYLTRANSFERASE
(Tribolium
castaneum) 		4 / 6 ILE A 225
GLU A 145
LEU A 152
LEU A 158
 None
 1.01A 1mt1B-5vg9A:
undetectable
1mt1C-5vg9A:
undetectable		 1mt1B-5vg9A:
18.64
1mt1C-5vg9A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA502_1
(YKOF)		 5vg9 PROTEIN-S-ISOPRENYLC
YSTEINE
O-METHYLTRANSFERASE
(Tribolium
castaneum) 		4 / 6 PHE A  13
ALA A  69
LEU A  71
SER A  17
 None
 1.05A 1sbrA-5vg9A:
undetectable
1sbrB-5vg9A:
undetectable		 1sbrA-5vg9A:
17.02
1sbrB-5vg9A:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_D_DVAD8_0
(GRAMICIDIN A)		 5vg9 PROTEIN-S-ISOPRENYLC
YSTEINE
O-METHYLTRANSFERASE
(Tribolium
castaneum) 		3 / 3 TRP A 218
VAL A 213
TRP A 215
 None
 1.19A 2xdcC-5vg9A:
undetectable
2xdcD-5vg9A:
undetectable		 2xdcC-5vg9A:
undetectable
2xdcD-5vg9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_F_DVAF8_0
(GRAMICIDIN A)		 5vg9 PROTEIN-S-ISOPRENYLC
YSTEINE
O-METHYLTRANSFERASE
(Tribolium
castaneum) 		3 / 3 TRP A 218
VAL A 213
TRP A 215
 None
 1.27A 2xdcE-5vg9A:
undetectable
2xdcF-5vg9A:
undetectable		 2xdcE-5vg9A:
undetectable
2xdcF-5vg9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_F_DVAF8_0
(VAL-GRAMICIDIN A)		 5vg9 PROTEIN-S-ISOPRENYLC
YSTEINE
O-METHYLTRANSFERASE
(Tribolium
castaneum) 		3 / 3 TRP A 218
VAL A 213
TRP A 215
 None
 1.21A 2y5mE-5vg9A:
undetectable
2y5mF-5vg9A:
undetectable		 2y5mE-5vg9A:
undetectable
2y5mF-5vg9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_D_DVAD8_0
(VAL-GRAMICIDIN A)		 5vg9 PROTEIN-S-ISOPRENYLC
YSTEINE
O-METHYLTRANSFERASE
(Tribolium
castaneum) 		3 / 3 TRP A 218
VAL A 213
TRP A 215
 None
 1.24A 2y6nC-5vg9A:
undetectable
2y6nD-5vg9A:
undetectable		 2y6nC-5vg9A:
undetectable
2y6nD-5vg9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_F_DVAF8_0
(VAL-GRAMICIDIN A)		 5vg9 PROTEIN-S-ISOPRENYLC
YSTEINE
O-METHYLTRANSFERASE
(Tribolium
castaneum) 		3 / 3 TRP A 218
VAL A 213
TRP A 215
 None
 1.23A 2y6nE-5vg9A:
undetectable
2y6nF-5vg9A:
undetectable		 2y6nE-5vg9A:
undetectable
2y6nF-5vg9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_D_DVAD8_0
(VAL-GRAMICIDIN A)		 5vg9 PROTEIN-S-ISOPRENYLC
YSTEINE
O-METHYLTRANSFERASE
(Tribolium
castaneum) 		3 / 3 TRP A 218
VAL A 213
TRP A 215
 None
 1.20A 3zq8C-5vg9A:
undetectable
3zq8D-5vg9A:
undetectable		 3zq8C-5vg9A:
undetectable
3zq8D-5vg9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_LCRA612_1
(SERUM ALBUMIN)		 5vg9 PROTEIN-S-ISOPRENYLC
YSTEINE
O-METHYLTRANSFERASE
(Tribolium
castaneum) 		5 / 9 LEU A  71
GLY A  72
LEU A  75
LEU A 101
ALA A 100
 None
 1.05A 5dqfA-5vg9A:
undetectable		 5dqfA-5vg9A:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_G_FK5G201_1
(FK506-BINDING
PROTEIN 1)		 5vg9 PROTEIN-S-ISOPRENYLC
YSTEINE
O-METHYLTRANSFERASE
(Tribolium
castaneum) 		3 / 3 ILE A 273
PRO A 274
ILE A 276
 None
 0.46A 5hw8F-5vg9A:
undetectable		 5hw8F-5vg9A:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MSD_A_BEZA1202_0
(CARBOXYLIC ACID
REDUCTASE)		 5vg9 PROTEIN-S-ISOPRENYLC
YSTEINE
O-METHYLTRANSFERASE
(Tribolium
castaneum) 		4 / 5 ILE A  66
PHE A 123
SER A   9
ALA A  63
 None
 1.11A 5msdA-5vg9A:
undetectable		 5msdA-5vg9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C71_B_NCTB501_1
(AMINE OXIDASE)		 5vg9 PROTEIN-S-ISOPRENYLC
YSTEINE
O-METHYLTRANSFERASE
(Tribolium
castaneum) 		4 / 8 LEU A 198
TYR A 262
GLU A 251
THR A 200
 SAH  A 301 (-4.4A)
None
None
None
 1.23A 6c71B-5vg9A:
undetectable		 6c71B-5vg9A:
27.47