SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vgc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U70_A_MTXA187_1
(DIHYDROFOLATE
REDUCTASE)		 5vgc NLEG5-1 EFFECTOR
(Enterobacteria
phage
YYZ-2008) 		5 / 12 ILE A 189
ALA A 181
GLN A 113
ASN A 111
LEU A 114
 None
CL  A 306 ( 4.6A)
None
None
None
 1.47A 1u70A-5vgcA:
undetectable		 1u70A-5vgcA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5vgc NLEG5-1 EFFECTOR
(Enterobacteria
phage
YYZ-2008) 		4 / 7 LEU A 133
GLN A 134
PHE A 202
PHE A 209
 None
 0.83A 3ag4P-5vgcA:
undetectable
3ag4W-5vgcA:
undetectable		 3ag4P-5vgcA:
undetectable
3ag4W-5vgcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_B_06XB501_1
(CYTOCHROME P450 2B6)		 5vgc NLEG5-1 EFFECTOR
(Enterobacteria
phage
YYZ-2008) 		4 / 7 ILE A  27
ILE A  19
LEU A  40
VAL A  45
 None
 0.84A 3ua5B-5vgcA:
undetectable		 3ua5B-5vgcA:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5vgc NLEG5-1 EFFECTOR
(Enterobacteria
phage
YYZ-2008) 		4 / 6 ILE A  27
LEU A  24
ARG A  39
THR A   6
 None
 1.10A 3wg7A-5vgcA:
undetectable
3wg7J-5vgcA:
undetectable		 3wg7A-5vgcA:
undetectable
3wg7J-5vgcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5vgc NLEG5-1 EFFECTOR
(Enterobacteria
phage
YYZ-2008) 		4 / 6 ILE A  27
LEU A  24
ARG A  39
THR A   6
 None
 0.81A 6nmfN-5vgcA:
undetectable
6nmfW-5vgcA:
undetectable		 6nmfN-5vgcA:
undetectable
6nmfW-5vgcA:
undetectable