SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vgs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MAG_A_DVAA6_0 (GRAMICIDIN A)	5vgs	LACHRYMATORY-FACTOR SYNTHASE (Allium cepa)	3 / 3	ALA A 27 VAL A 25 TRP A 133	None None 9A7 A 202 (-3.4A)	0.93A	1magA-5vgsA: undetectable	1magA-5vgsA: 8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MAG_B_DVAB6_0 (GRAMICIDIN A)	5vgs	LACHRYMATORY-FACTOR SYNTHASE (Allium cepa)	3 / 3	ALA A 27 VAL A 25 TRP A 133	None None 9A7 A 202 (-3.4A)	0.94A	1magB-5vgsA: undetectable	1magB-5vgsA: 8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NRM_A_DVAA6_0 (GRAMICIDIN A)	5vgs	LACHRYMATORY-FACTOR SYNTHASE (Allium cepa)	3 / 3	ALA A 27 VAL A 25 TRP A 133	None None 9A7 A 202 (-3.4A)	0.93A	1nrmA-5vgsA: undetectable	1nrmA-5vgsA: 8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NRM_B_DVAB6_0 (GRAMICIDIN A)	5vgs	LACHRYMATORY-FACTOR SYNTHASE (Allium cepa)	3 / 3	ALA A 27 VAL A 25 TRP A 133	None None 9A7 A 202 (-3.4A)	0.93A	1nrmB-5vgsA: undetectable	1nrmB-5vgsA: 8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NT6_A_DVAA6_0 (GRAMICIDIN C)	5vgs	LACHRYMATORY-FACTOR SYNTHASE (Allium cepa)	3 / 3	ALA A 27 VAL A 25 TRP A 133	None None 9A7 A 202 (-3.4A)	0.84A	1nt6A-5vgsA: undetectable	1nt6A-5vgsA: 7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NT6_B_DVAB6_0 (GRAMICIDIN C)	5vgs	LACHRYMATORY-FACTOR SYNTHASE (Allium cepa)	3 / 3	ALA A 27 VAL A 25 TRP A 133	None None 9A7 A 202 (-3.4A)	0.84A	1nt6B-5vgsA: undetectable	1nt6B-5vgsA: 7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ELZ_B_CHDB153_0 (ILEAL BILE ACID-BINDING PROTEIN)	5vgs	LACHRYMATORY-FACTOR SYNTHASE (Allium cepa)	4 / 6	ILE A 17 PHE A 84 PHE A 104 TYR A 114	None 9A7 A 202 ( 3.5A) 9A7 A 202 ( 4.2A) 9A7 A 202 ( 4.3A)	0.99A	3elzB-5vgsA: 2.6	3elzB-5vgsA: 24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K8M_A_ACRA720_1 (ALPHA-AMYLASE, SUSG)	5vgs	LACHRYMATORY-FACTOR SYNTHASE (Allium cepa)	4 / 7	TYR A 100 TRP A 38 LEU A 93 ASN A 95	None	1.28A	3k8mA-5vgsA: undetectable	3k8mA-5vgsA: 14.60

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1MAG_A_DVAA6_0","GRAMICIDIN A","5vgs","LACHRYMATORY-FACTOR SYNTHASE","Allium cepa",3,"ALA A  27;VAL A  25;TRP A 133","None;None;9A7 A 202 (-3.4A)","0.93A","1magA-5vgsA:undetectable","1magA-5vgsA:8.33"],["1MAG_B_DVAB6_0","GRAMICIDIN A","5vgs","LACHRYMATORY-FACTOR SYNTHASE","Allium cepa",3,"ALA A  27;VAL A  25;TRP A 133","None;None;9A7 A 202 (-3.4A)","0.94A","1magB-5vgsA:undetectable","1magB-5vgsA:8.33"],["1NRM_A_DVAA6_0","GRAMICIDIN A","5vgs","LACHRYMATORY-FACTOR SYNTHASE","Allium cepa",3,"ALA A  27;VAL A  25;TRP A 133","None;None;9A7 A 202 (-3.4A)","0.93A","1nrmA-5vgsA:undetectable","1nrmA-5vgsA:8.33"],["1NRM_B_DVAB6_0","GRAMICIDIN A","5vgs","LACHRYMATORY-FACTOR SYNTHASE","Allium cepa",3,"ALA A  27;VAL A  25;TRP A 133","None;None;9A7 A 202 (-3.4A)","0.93A","1nrmB-5vgsA:undetectable","1nrmB-5vgsA:8.33"],["1NT6_A_DVAA6_0","GRAMICIDIN C","5vgs","LACHRYMATORY-FACTOR SYNTHASE","Allium cepa",3,"ALA A  27;VAL A  25;TRP A 133","None;None;9A7 A 202 (-3.4A)","0.84A","1nt6A-5vgsA:undetectable","1nt6A-5vgsA:7.64"],["1NT6_B_DVAB6_0","GRAMICIDIN C","5vgs","LACHRYMATORY-FACTOR SYNTHASE","Allium cepa",3,"ALA A  27;VAL A  25;TRP A 133","None;None;9A7 A 202 (-3.4A)","0.84A","1nt6B-5vgsA:undetectable","1nt6B-5vgsA:7.64"],["3ELZ_B_CHDB153_0","ILEAL BILE ACID-BINDING PROTEIN","5vgs","LACHRYMATORY-FACTOR SYNTHASE","Allium cepa",4,"ILE A  17;PHE A  84;PHE A 104;TYR A 114","None;9A7 A 202 ( 3.5A);9A7 A 202 ( 4.2A);9A7 A 202 ( 4.3A)","0.99A","3elzB-5vgsA:2.6","3elzB-5vgsA:24.56"],["3K8M_A_ACRA720_1","ALPHA-AMYLASE, SUSG","5vgs","LACHRYMATORY-FACTOR SYNTHASE","Allium cepa",4,"TYR A 100;TRP A  38;LEU A  93;ASN A  95","None","1.28A","3k8mA-5vgsA:undetectable","3k8mA-5vgsA:14.60"]]