SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vgt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1A29_A_TFPA154_1 (CALMODULIN)	5vgt	GENE 7 PROTEIN (Shigella virus Sf6)	5 / 10	GLU A 71 ALA A 58 MET A 45 LEU A 41 GLU A 9	None	1.11A	1a29A-5vgtA: undetectable	1a29A-5vgtA: 20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OZ7_A_CA4A1_2 (ANDROGEN RECEPTOR)	5vgt	GENE 7 PROTEIN (Shigella virus Sf6)	4 / 6	LEU A 5 TRP A 48 MET A 44 LEU A 86	None	1.47A	2oz7A-5vgtA: undetectable	2oz7A-5vgtA: 14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U5K_C_08JC3_1 (BROMODOMAIN-CONTAINI NG PROTEIN 4)	5vgt	GENE 7 PROTEIN (Shigella virus Sf6)	4 / 8	VAL A 102 LEU A 87 LEU A 91 ILE A 20	None	0.90A	3u5kC-5vgtA: undetectable	3u5kC-5vgtA: 20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KLR_A_CHDA505_0 (FERROCHELATASE, MITOCHONDRIAL)	5vgt	GENE 7 PROTEIN (Shigella virus Sf6)	4 / 5	LEU A 74 PRO A 75 LEU A 5 ILE A 10	None	0.90A	4klrA-5vgtA: undetectable	4klrA-5vgtA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QTU_D_SAMD301_1 (PUTATIVE METHYLTRANSFERASE BUD23)	5vgt	GENE 7 PROTEIN (Shigella virus Sf6)	4 / 5	LEU A 103 SER A 104 ASP A 111 ASP A 116	None None None MG A 204 (-4.2A)	1.29A	4qtuD-5vgtA: undetectable	4qtuD-5vgtA: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1A29_A_TFPA154_1","CALMODULIN","5vgt","GENE 7 PROTEIN","Shigella virus Sf6",5,"GLU A  71;ALA A  58;MET A  45;LEU A  41;GLU A   9","None","1.11A","1a29A-5vgtA:undetectable","1a29A-5vgtA:20.81"],["2OZ7_A_CA4A1_2","ANDROGEN RECEPTOR","5vgt","GENE 7 PROTEIN","Shigella virus Sf6",4,"LEU A   5;TRP A  48;MET A  44;LEU A  86","None","1.47A","2oz7A-5vgtA:undetectable","2oz7A-5vgtA:14.57"],["3U5K_C_08JC3_1","BROMODOMAIN-CONTAINING PROTEIN 4","5vgt","GENE 7 PROTEIN","Shigella virus Sf6",4,"VAL A 102;LEU A  87;LEU A  91;ILE A  20","None","0.90A","3u5kC-5vgtA:undetectable","3u5kC-5vgtA:20.63"],["4KLR_A_CHDA505_0","FERROCHELATASE, MITOCHONDRIAL","5vgt","GENE 7 PROTEIN","Shigella virus Sf6",4,"LEU A  74;PRO A  75;LEU A   5;ILE A  10","None","0.90A","4klrA-5vgtA:undetectable","4klrA-5vgtA:undetectable"],["4QTU_D_SAMD301_1","PUTATIVE METHYLTRANSFERASE BUD23","5vgt","GENE 7 PROTEIN","Shigella virus Sf6",4,"LEU A 103;SER A 104;ASP A 111;ASP A 116","None;None;None; MG A 204 (-4.2A)","1.29A","4qtuD-5vgtA:undetectable","4qtuD-5vgtA:undetectable"]]