SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vh1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HA2_A_SCKA901_1 (ACETYLCHOLINESTERASE)	5vh1	GAMMA S-CRYSTALLIN (Gallus gallus)	4 / 8	TYR A 139 TRP A 72 TYR A 66 HIS A 71	None	1.49A	2ha2A-5vh1A: undetectable	2ha2A-5vh1A: 14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HA2_B_SCKB951_1 (ACETYLCHOLINESTERASE)	5vh1	GAMMA S-CRYSTALLIN (Gallus gallus)	4 / 8	TYR A 139 TRP A 72 TYR A 66 HIS A 71	None	1.49A	2ha2B-5vh1A: undetectable	2ha2B-5vh1A: 14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QEI_A_CXXA802_1 (TRANSPORTER)	5vh1	GAMMA S-CRYSTALLIN (Gallus gallus)	4 / 6	SER A 174 ARG A 173 PHE A 172 PHE A 108	None	1.14A	2qeiA-5vh1A: undetectable	2qeiA-5vh1A: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_G_SVRG506_2 (PHOSPHOLIPASE A2)	5vh1	GAMMA S-CRYSTALLIN (Gallus gallus)	4 / 5	VAL A 60 VAL A 47 PHE A 138 ARG A 51	None	1.07A	3bjwB-5vh1A: undetectable	3bjwB-5vh1A: 17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KM6_A_EAAA222_1 (GLUTATHIONE S-TRANSFERASE P)	5vh1	GAMMA S-CRYSTALLIN (Gallus gallus)	5 / 10	TYR A 156 VAL A 131 GLY A 154 VAL A 137 GLN A 148	None	1.27A	3km6A-5vh1A: undetectable	3km6A-5vh1A: 21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KMO_A_EAAA214_1 (GLUTATHIONE S-TRANSFERASE P)	5vh1	GAMMA S-CRYSTALLIN (Gallus gallus)	5 / 9	TYR A 156 VAL A 131 GLY A 154 VAL A 137 GLN A 148	None	1.29A	3kmoA-5vh1A: undetectable	3kmoA-5vh1A: 21.61

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2HA2_A_SCKA901_1","ACETYLCHOLINESTERASE","5vh1","GAMMA S-CRYSTALLIN","Gallus gallus",4,"TYR A 139;TRP A  72;TYR A  66;HIS A  71","None","1.49A","2ha2A-5vh1A:undetectable","2ha2A-5vh1A:14.92"],["2HA2_B_SCKB951_1","ACETYLCHOLINESTERASE","5vh1","GAMMA S-CRYSTALLIN","Gallus gallus",4,"TYR A 139;TRP A  72;TYR A  66;HIS A  71","None","1.49A","2ha2B-5vh1A:undetectable","2ha2B-5vh1A:14.92"],["2QEI_A_CXXA802_1","TRANSPORTER","5vh1","GAMMA S-CRYSTALLIN","Gallus gallus",4,"SER A 174;ARG A 173;PHE A 172;PHE A 108","None","1.14A","2qeiA-5vh1A:undetectable","2qeiA-5vh1A:16.67"],["3BJW_G_SVRG506_2","PHOSPHOLIPASE A2;PHOSPHOLIPASE A2","5vh1","GAMMA S-CRYSTALLIN","Gallus gallus",4,"VAL A  60;VAL A  47;PHE A 138;ARG A  51","None","1.07A","3bjwB-5vh1A:undetectable","3bjwB-5vh1A:17.42"],["3KM6_A_EAAA222_1","GLUTATHIONE S-TRANSFERASE P","5vh1","GAMMA S-CRYSTALLIN","Gallus gallus",5,"TYR A 156;VAL A 131;GLY A 154;VAL A 137;GLN A 148","None","1.27A","3km6A-5vh1A:undetectable","3km6A-5vh1A:21.61"],["3KMO_A_EAAA214_1","GLUTATHIONE S-TRANSFERASE P","5vh1","GAMMA S-CRYSTALLIN","Gallus gallus",5,"TYR A 156;VAL A 131;GLY A 154;VAL A 137;GLN A 148","None","1.29A","3kmoA-5vh1A:undetectable","3kmoA-5vh1A:21.61"]]