SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vh2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQT_C_C5EC301_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5vh2 CADHERIN-23
(Mus
musculus) 		4 / 8 VAL A1207
CYH A1274
TYR A1190
ILE A1235
 None
 1.25A 4bqtC-5vh2A:
undetectable
4bqtD-5vh2A:
undetectable		 4bqtC-5vh2A:
undetectable
4bqtD-5vh2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_F_SC2F1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 5vh2 CADHERIN-23
(Mus
musculus) 		3 / 3 VAL A1208
GLN A1189
CYH A1274
 None
 0.84A 5icxC-5vh2A:
4.9
5icxF-5vh2A:
undetectable		 5icxC-5vh2A:
18.40
5icxF-5vh2A:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_C_GLYC713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 5vh2 CADHERIN-23
(Mus
musculus) 		3 / 3 GLN A1189
TYR A1277
ASN A1191
 None
 1.06A 6dwdC-5vh2A:
undetectable		 6dwdC-5vh2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_D8ZA831_0
(GEPHYRIN)		 5vh2 CADHERIN-23
(Mus
musculus) 		5 / 11 ASP A1246
ILE A1201
ILE A1225
TYR A1256
MET A1258
 None
 1.28A 6fgdA-5vh2A:
undetectable		 6fgdA-5vh2A:
23.91