SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vhf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_1
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 5vhf 26S PROTEASOME
NON-ATPASE
REGULATORY SUBUNIT 3
(Homo
sapiens) 		4 / 4 THR V 327
LEU V 331
VAL V 334
LEU V 338
 None
 0.94A 1fbmB-5vhfV:
2.8		 1fbmB-5vhfV:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TBF_A_VIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5vhf 26S PROTEASOME
NON-ATPASE
REGULATORY SUBUNIT 3
(Homo
sapiens) 		5 / 9 LEU V 394
LEU V 338
VAL V 367
ALA V 366
LEU V 379
 None
 1.20A 1tbfA-5vhfV:
undetectable		 1tbfA-5vhfV:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_B_SAMB501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 5vhf 26S PROTEASOME
NON-ATPASE
REGULATORY SUBUNIT 3
(Homo
sapiens) 		4 / 7 TYR V 360
THR V 391
THR V 393
VAL V 334
 None
 1.09A 2fb2B-5vhfV:
undetectable		 2fb2B-5vhfV:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_B_VIAB902_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5vhf 26S PROTEASOME
NON-ATPASE
REGULATORY SUBUNIT 3
(Homo
sapiens) 		5 / 12 HIS V 453
ALA V 434
ILE V 437
ALA V 449
ILE V 447
 None
 1.14A 2h42B-5vhfV:
undetectable		 2h42B-5vhfV:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F5U_A_CQNA610_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 5vhf 26S PROTEASOME
NON-ATPASE
REGULATORY SUBUNIT 3
(Homo
sapiens) 		5 / 10 VAL V 367
ALA V 366
LEU V 337
LEU V 379
LEU V 398
 None
 0.87A 6f5uA-5vhfV:
undetectable
6f5uB-5vhfV:
undetectable		 6f5uA-5vhfV:
17.78
6f5uB-5vhfV:
18.86