SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vhv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT3_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5vhv ALKYLPURINE DNA
GLYCOSYLASE ALKC
(Pseudomonas
fluorescens) 		4 / 7 LEU A 162
LEU A 128
MET A 139
LEU A 153
 None
 0.85A 1kt3A-5vhvA:
undetectable		 1kt3A-5vhvA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA507_0
(CHORISMATE SYNTHASE)		 5vhv ALKYLPURINE DNA
GLYCOSYLASE ALKC
(Pseudomonas
fluorescens) 		3 / 3 LEU A  45
ASN A  14
ARG A  53
 None
 0.79A 2qhfA-5vhvA:
undetectable		 2qhfA-5vhvA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 5vhv ALKYLPURINE DNA
GLYCOSYLASE ALKC
(Pseudomonas
fluorescens) 		4 / 5 TYR A  69
ARG A 106
THR A  74
LEU A  76
 None
 1.39A 3ag2J-5vhvA:
undetectable		 3ag2J-5vhvA:
9.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_B_MXMB807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5vhv ALKYLPURINE DNA
GLYCOSYLASE ALKC
(Pseudomonas
fluorescens) 		5 / 12 LEU A  18
VAL A  64
LEU A  61
ALA A  34
LEU A  38
 None
 1.08A 4o1zB-5vhvA:
undetectable		 4o1zB-5vhvA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 5vhv ALKYLPURINE DNA
GLYCOSYLASE ALKC
(Pseudomonas
fluorescens) 		4 / 7 ASP A 203
ARG A 159
GLY A 157
GLU A 156
 None
 1.03A 5btfA-5vhvA:
undetectable
5btfC-5vhvA:
undetectable
5btfD-5vhvA:
undetectable		 5btfA-5vhvA:
22.24
5btfC-5vhvA:
22.24
5btfD-5vhvA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5vhv ALKYLPURINE DNA
GLYCOSYLASE ALKC
(Pseudomonas
fluorescens) 		4 / 4 TYR A  69
ARG A 106
THR A  74
LEU A  76
 None
 1.38A 5wauj-5vhvA:
undetectable		 5wauj-5vhvA:
9.70