SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vi4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5vi4 INTERLEUKIN-1
RECEPTOR ACCESSORY
PROTEIN
(Mus
musculus) 		5 / 11 TYR C 166
PHE C 223
PHE C 127
LEU C 129
VAL C 131
 None
 1.40A 1q23J-5vi4C:
undetectable		 1q23J-5vi4C:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 5vi4 INTERLEUKIN-1
RECEPTOR-LIKE 1
(Mus
musculus) 		3 / 3 HIS B 168
ASP B 143
ASN B 146
 None
None
NAG  B 401 (-2.0A)
 0.87A 1wg8B-5vi4B:
undetectable		 1wg8B-5vi4B:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B304_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5vi4 INTERLEUKIN-1
RECEPTOR-LIKE 1
(Mus
musculus) 		4 / 5 ASN B 118
THR B 207
SER B 205
ARG B 129
 None
 1.20A 3hlwB-5vi4B:
undetectable		 3hlwB-5vi4B:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGL_A_RZXA257_1
(CARBOXY-TERMINAL
DOMAIN RNA
POLYMERASE II
POLYPEPTIDE A SMALL
PHOSPHATASE 1)		 5vi4 INTERLEUKIN-1
RECEPTOR-LIKE 1
INTERLEUKIN-33
(Mus
musculus) 		4 / 7 ASP A 225
PHE B 206
VAL B 177
ILE B 174
 None
 0.97A 3pglA-5vi4A:
undetectable		 3pglA-5vi4A:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ECK_B_FOLB703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5vi4 INTERLEUKIN-33
(Mus
musculus) 		5 / 12 VAL A 144
LEU A 204
MET A 183
PHE A 217
VAL A 131
 None
 0.95A 4eckB-5vi4A:
undetectable		 4eckB-5vi4A:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_B_FOLB301_1
(FOLATE RECEPTOR
ALPHA)		 5vi4 INTERLEUKIN-33
INTERLEUKIN-1
RECEPTOR-LIKE 1
(Mus
musculus;
Mus
musculus) 		3 / 3 ASP A 145
TRP B  54
SER B  30
 None
 0.95A 4lrhB-5vi4A:
undetectable		 4lrhB-5vi4A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_1
(DIHYDROPTEROATE
SYNTHASE DHPS)		 5vi4 INTERLEUKIN-33
INTERLEUKIN-1
RECEPTOR-LIKE 1
(Mus
musculus;
Mus
musculus) 		3 / 3 LYS A 177
ASN B 312
ASP A 175
 None
 0.87A 4o1eA-5vi4A:
undetectable		 4o1eA-5vi4A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_F_ACTF1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 5vi4 INTERLEUKIN-1
RECEPTOR ACCESSORY
PROTEIN
(Mus
musculus) 		3 / 3 TYR C  71
THR C  73
THR C 113
 None
 0.75A 5aoxE-5vi4C:
2.0		 5aoxE-5vi4C:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_2
(WTFP-TAG,GP41)		 5vi4 INTERLEUKIN-1
RECEPTOR ACCESSORY
PROTEIN
(Mus
musculus) 		3 / 3 LEU C  66
LEU C  68
TRP C  70
 None
 0.71A 5nwuA-5vi4C:
undetectable		 5nwuA-5vi4C:
7.45