SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vic'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I9J_H_TESH1010_1
(RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT HEAVY
CHAIN
RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT LIGHT
CHAIN)		 5vic FAB HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER H  35
TRP H  47
SER H  50
VAL H 100
TYR H  58
 None
 1.06A 1i9jH-5vicH:
27.6
1i9jL-5vicH:
14.9		 1i9jH-5vicH:
62.83
1i9jL-5vicH:
27.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA501_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 5vic FAB HEAVY CHAIN
(Homo
sapiens) 		4 / 5 TYR H  90
LEU H  80
LEU H  82
ARG H  66
 None
 1.26A 4em2A-5vicH:
undetectable		 4em2A-5vicH:
21.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MTH_A_ACTA302_0
(ANTIBODY FAB HEAVY
CHAIN)		 5vic FAB HEAVY CHAIN
(Homo
sapiens) 		4 / 5 SER H 112
ALA H 114
PHE H 146
LEU H 170
 None
 0.36A 5mthA-5vicH:
17.2		 5mthA-5vicH:
54.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_2
(CYTOCHROME P450 3A5)		 5vic FAB HEAVY CHAIN
(Homo
sapiens) 		4 / 5 PHE H  91
PHE H 100
LEU H  45
LEU H  80
 None
 0.99A 5veuH-5vicH:
undetectable		 5veuH-5vicH:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRZ_A_H8JA1206_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 5vic FAB HEAVY CHAIN
(Homo
sapiens) 		5 / 12 VAL H 207
THR H 205
VAL H 211
GLY H 118
VAL H 152
 None
 1.09A 6drzA-5vicH:
undetectable		 6drzA-5vicH:
18.66