SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5viq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3003_0
(BETA-CARBONIC
ANHYDRASE)		 5viq MONOMERIC
NEAR-INFRARED
FLUORESCENT PROTEIN
MIRFP709
(Rhodopseudomonas
palustris) 		4 / 8 ASP A 165
VAL A 167
HIS A 285
GLY A 163
 None
 0.93A 1ekjA-5viqA:
undetectable
1ekjB-5viqA:
undetectable		 1ekjA-5viqA:
20.89
1ekjB-5viqA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_A_FLPA1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5viq MONOMERIC
NEAR-INFRARED
FLUORESCENT PROTEIN
MIRFP709
(Rhodopseudomonas
palustris) 		5 / 12 LEU A  75
PHE A 246
GLY A  35
ALA A  36
LEU A  58
 None
 0.98A 2aylA-5viqA:
undetectable		 2aylA-5viqA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_A_FCNA1199_1
(EPOXIDASE)		 5viq MONOMERIC
NEAR-INFRARED
FLUORESCENT PROTEIN
MIRFP709
(Rhodopseudomonas
palustris) 		5 / 9 ARG A 248
TYR A 210
LEU A 280
HIS A 254
ALA A 268
 BLA  A 401 (-3.0A)
BLA  A 401 (-4.0A)
BLA  A 401 ( 4.8A)
BLA  A 401 (-3.8A)
BLA  A 401 (-3.3A)
 1.31A 2bnnA-5viqA:
undetectable
2bnnB-5viqA:
undetectable		 2bnnA-5viqA:
22.02
2bnnB-5viqA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5viq MONOMERIC
NEAR-INFRARED
FLUORESCENT PROTEIN
MIRFP709
(Rhodopseudomonas
palustris) 		4 / 7 LEU A 255
GLN A 256
PHE A 257
LEU A 218
 None
None
BLA  A 401 (-4.3A)
None
 0.99A 2dysP-5viqA:
undetectable
2dysW-5viqA:
undetectable		 2dysP-5viqA:
19.88
2dysW-5viqA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5viq MONOMERIC
NEAR-INFRARED
FLUORESCENT PROTEIN
MIRFP709
(Rhodopseudomonas
palustris) 		4 / 6 LEU A 255
GLN A 256
PHE A 257
LEU A 218
 None
None
BLA  A 401 (-4.3A)
None
 0.96A 2einP-5viqA:
undetectable
2einW-5viqA:
undetectable		 2einP-5viqA:
19.88
2einW-5viqA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5viq MONOMERIC
NEAR-INFRARED
FLUORESCENT PROTEIN
MIRFP709
(Rhodopseudomonas
palustris) 		4 / 6 LEU A 255
GLN A 256
PHE A 257
LEU A 218
 None
None
BLA  A 401 (-4.3A)
None
 0.93A 2zxwP-5viqA:
undetectable
2zxwW-5viqA:
undetectable		 2zxwP-5viqA:
19.88
2zxwW-5viqA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5viq MONOMERIC
NEAR-INFRARED
FLUORESCENT PROTEIN
MIRFP709
(Rhodopseudomonas
palustris) 		4 / 6 LEU A 255
GLN A 256
PHE A 257
LEU A 218
 None
None
BLA  A 401 (-4.3A)
None
 0.96A 3ag1C-5viqA:
undetectable
3ag1J-5viqA:
undetectable		 3ag1C-5viqA:
19.88
3ag1J-5viqA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_1
(CYTOCHROME P450 2R1)		 5viq MONOMERIC
NEAR-INFRARED
FLUORESCENT PROTEIN
MIRFP709
(Rhodopseudomonas
palustris) 		4 / 5 ALA A  50
LEU A 247
GLY A  35
THR A 103
 None
 0.92A 3dl9A-5viqA:
undetectable		 3dl9A-5viqA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5viq MONOMERIC
NEAR-INFRARED
FLUORESCENT PROTEIN
MIRFP709
(Rhodopseudomonas
palustris) 		5 / 12 LEU A  75
PHE A 246
GLY A  35
ALA A  36
LEU A  58
 None
 0.97A 3n8xB-5viqA:
undetectable		 3n8xB-5viqA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_B_032B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 5viq MONOMERIC
NEAR-INFRARED
FLUORESCENT PROTEIN
MIRFP709
(Rhodopseudomonas
palustris) 		4 / 5 ILE A  79
PHE A  57
SER A  41
HIS A  45
 None
 1.40A 4rzvB-5viqA:
undetectable		 4rzvB-5viqA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_2
(-)		 5viq MONOMERIC
NEAR-INFRARED
FLUORESCENT PROTEIN
MIRFP709
(Rhodopseudomonas
palustris) 		4 / 8 VAL A 282
ASN A 195
TYR A 197
GLU A 190
 BLA  A 401 (-4.8A)
None
BLA  A 401 (-3.4A)
None
 1.33A 6gneB-5viqA:
undetectable		 6gneB-5viqA:
18.38