SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5viu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_C_T44C128_1
(TRANSTHYRETIN)		 5viu ACETYLORNITHINE
AMINOTRANSFERASE
(Elizabethkingia
anophelis) 		5 / 11 LEU A 274
GLU A  91
ALA A 272
LEU A 257
VAL A 270
 None
 1.22A 1ictA-5viuA:
undetectable
1ictC-5viuA:
undetectable		 1ictA-5viuA:
15.74
1ictC-5viuA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA699_1
(ADENOSINE KINASE)		 5viu ACETYLORNITHINE
AMINOTRANSFERASE
(Elizabethkingia
anophelis) 		5 / 12 LEU A 274
GLY A 293
GLY A 294
ASN A 295
TYR A  90
 None
 1.04A 1likA-5viuA:
undetectable		 1likA-5viuA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_2
(POL POLYPROTEIN)		 5viu ACETYLORNITHINE
AMINOTRANSFERASE
(Elizabethkingia
anophelis) 		5 / 12 GLY A  99
ASP A 101
ILE A 256
ILE A 279
ALA A 231
 None
 1.02A 1sguB-5viuA:
undetectable		 1sguB-5viuA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_1
(TRANSTHYRETIN)		 5viu ACETYLORNITHINE
AMINOTRANSFERASE
(Elizabethkingia
anophelis) 		4 / 6 GLU A  91
ALA A 272
LEU A 257
VAL A 270
 None
 1.13A 1sn5A-5viuA:
undetectable		 1sn5A-5viuA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y4N_B_PACB503_0
(PHENYLACETATE-COENZY
ME A LIGASE)		 5viu ACETYLORNITHINE
AMINOTRANSFERASE
(Elizabethkingia
anophelis) 		4 / 4 SER A  50
GLY A 237
GLY A 260
LYS A 261
 None
 1.47A 2y4nB-5viuA:
3.6		 2y4nB-5viuA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_D_VD3D2001_1
(VITAMIN D
HYDROXYLASE)		 5viu ACETYLORNITHINE
AMINOTRANSFERASE
(Elizabethkingia
anophelis) 		5 / 12 ILE A 329
LEU A 332
LEU A 365
ILE A 384
LEU A 374
 None
 1.02A 3a50D-5viuA:
undetectable		 3a50D-5viuA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_0
(REPRESSOR PROTEIN
MPHR(A))		 5viu ACETYLORNITHINE
AMINOTRANSFERASE
(Elizabethkingia
anophelis) 		5 / 12 THR A 241
LYS A 345
VAL A 252
TYR A 208
ILE A 179
 None
None
None
None
EDO  A 506 (-4.8A)
 1.24A 3frqA-5viuA:
undetectable		 3frqA-5viuA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_B_FLPB701_1
(CYCLOOXYGENASE-2)		 5viu ACETYLORNITHINE
AMINOTRANSFERASE
(Elizabethkingia
anophelis) 		5 / 11 VAL A 309
LEU A 314
LEU A 244
GLY A 265
ALA A 262
 None
None
CIT  A 509 (-4.2A)
None
None
 1.25A 3pghB-5viuA:
undetectable		 3pghB-5viuA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ENH_A_FVXA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 5viu ACETYLORNITHINE
AMINOTRANSFERASE
(Elizabethkingia
anophelis) 		5 / 12 LEU A 374
ILE A 404
ALA A 362
GLY A 381
ALA A 376
 None
 1.03A 4enhA-5viuA:
undetectable		 4enhA-5viuA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 5viu ACETYLORNITHINE
AMINOTRANSFERASE
(Elizabethkingia
anophelis) 		5 / 12 ASN A 278
VAL A 282
VAL A 117
ALA A 116
LEU A 119
 None
 0.96A 5kocA-5viuA:
undetectable		 5kocA-5viuA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 5viu ACETYLORNITHINE
AMINOTRANSFERASE
(Elizabethkingia
anophelis) 		5 / 12 ASP A 281
VAL A 282
VAL A 117
ALA A 116
LEU A 119
 None
 1.03A 5kocA-5viuA:
undetectable		 5kocA-5viuA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_1
(PROTEASE E35D-APV)		 5viu ACETYLORNITHINE
AMINOTRANSFERASE
(Elizabethkingia
anophelis) 		5 / 9 ALA A 195
ASP A 255
ILE A 279
VAL A 113
ILE A 230
 None
EDO  A 505 ( 4.2A)
None
None
None
 1.17A 5kr0A-5viuA:
undetectable		 5kr0A-5viuA:
12.41