SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vj4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_A_CAMA1416_0
(CYTOCHROME P450-CAM)		 5vj4 UNCHARACTERIZED
PROTEIN
(Borrelia
turicatae) 		4 / 8 LEU A 168
THR A 226
VAL A 263
ASP A 260
 None
 1.17A 1uyuA-5vj4A:
undetectable		 1uyuA-5vj4A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 5vj4 UNCHARACTERIZED
PROTEIN
(Borrelia
turicatae) 		4 / 8 LEU A 168
THR A 226
VAL A 263
ASP A 260
 None
 1.13A 1uyuB-5vj4A:
undetectable		 1uyuB-5vj4A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5vj4 UNCHARACTERIZED
PROTEIN
(Borrelia
turicatae) 		5 / 12 ILE A 219
VAL A 227
ILE A 194
ILE A 197
VAL A 263
 None
 0.95A 3w68C-5vj4A:
undetectable		 3w68C-5vj4A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 5vj4 UNCHARACTERIZED
PROTEIN
(Borrelia
turicatae) 		5 / 12 LEU A 230
GLY A 234
ILE A 240
PHE A 294
ALA A 288
 None
 1.11A 4a6eA-5vj4A:
undetectable		 4a6eA-5vj4A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX5_B_MIYB1103_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 5vj4 UNCHARACTERIZED
PROTEIN
(Borrelia
turicatae) 		5 / 12 GLY A 190
SER A 189
ILE A 219
VAL A 218
PHE A 184
 None
 1.18A 4dx5B-5vj4A:
2.3		 4dx5B-5vj4A:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_C_NCTC501_1
(CYTOCHROME P450 2A13)		 5vj4 UNCHARACTERIZED
PROTEIN
(Borrelia
turicatae) 		4 / 7 PHE A 271
ALA A 193
LEU A 181
LEU A 210
 None
 0.91A 4ejgC-5vj4A:
undetectable		 4ejgC-5vj4A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_C_C2FC302_0
(THYMIDYLATE SYNTHASE)		 5vj4 UNCHARACTERIZED
PROTEIN
(Borrelia
turicatae) 		5 / 11 ILE A 222
LEU A 230
GLY A 267
PHE A 270
VAL A 284
 None
 1.33A 4fogC-5vj4A:
undetectable		 4fogC-5vj4A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H1N_A_CGEA505_1
(CYTOCHROME P450 2B4)		 5vj4 UNCHARACTERIZED
PROTEIN
(Borrelia
turicatae) 		5 / 11 ILE A 319
ILE A 352
THR A 413
ILE A 411
VAL A 348
 None
None
SO4  A 505 (-3.6A)
None
None
 1.18A 4h1nA-5vj4A:
undetectable		 4h1nA-5vj4A:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5vj4 UNCHARACTERIZED
PROTEIN
(Borrelia
turicatae) 		4 / 8 ILE A 360
GLU A 364
GLU A 361
ILE A 354
 None
None
None
SO4  A 505 ( 4.7A)
 0.87A 4mj8A-5vj4A:
undetectable		 4mj8A-5vj4A:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y1D_D_DVAD5_0
(CYCLIC HEXAPEPTIDE
CYC[NDPOPPKID]
INTEGRASE)		 5vj4 UNCHARACTERIZED
PROTEIN
(Borrelia
turicatae) 		3 / 3 GLU A 364
LYS A 426
ASN A 367
 None
 1.08A 4y1dA-5vj4A:
undetectable
4y1dD-5vj4A:
undetectable		 4y1dA-5vj4A:
18.75
4y1dD-5vj4A:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UBB_A_SAMA301_1
(ALPHA N-TERMINAL
PROTEIN
METHYLTRANSFERASE 1B)		 5vj4 UNCHARACTERIZED
PROTEIN
(Borrelia
turicatae) 		4 / 5 GLY A 415
ARG A 419
ASP A 414
MET A 412
 SO4  A 505 (-4.0A)
SO4  A 502 (-3.2A)
None
SO4  A 505 ( 4.8A)
 1.40A 5ubbA-5vj4A:
undetectable		 5ubbA-5vj4A:
17.91