SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vjc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3004_1
(SERUM ALBUMIN)		 5vjc PROTEIN MINI
SPINDLES
(Drosophila
melanogaster) 		4 / 6 PHE A1259
PHE A1277
LEU A1300
VAL A1312
 None
 1.00A 1hk1A-5vjcA:
undetectable		 1hk1A-5vjcA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3004_1
(SERUM ALBUMIN)		 5vjc PROTEIN MINI
SPINDLES
(Drosophila
melanogaster) 		4 / 7 PHE A1259
PHE A1277
LEU A1300
VAL A1312
 None
 1.00A 1hk3A-5vjcA:
2.6		 1hk3A-5vjcA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_A_ADNA300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 5vjc PROTEIN MINI
SPINDLES
(Drosophila
melanogaster) 		5 / 11 ALA A1356
ARG A1357
ILE A1374
LEU A1392
THR A1385
 None
 1.27A 3kw2A-5vjcA:
undetectable		 3kw2A-5vjcA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB323_0
(INVASIN IPAD)		 5vjc PROTEIN MINI
SPINDLES
(Drosophila
melanogaster) 		4 / 7 ILE A1339
VAL A1377
LEU A1380
SER A1381
 None
 0.70A 3r9vA-5vjcA:
undetectable
3r9vB-5vjcA:
undetectable		 3r9vA-5vjcA:
23.77
3r9vB-5vjcA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC610_0
(GBAA_1210 PROTEIN)		 5vjc PROTEIN MINI
SPINDLES
(Drosophila
melanogaster) 		3 / 3 ASN A1228
ALA A1189
ARG A1157
 None
 0.78A 3tj7C-5vjcA:
undetectable
3tj7D-5vjcA:
undetectable		 3tj7C-5vjcA:
24.44
3tj7D-5vjcA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNA_A_SALA1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5vjc PROTEIN MINI
SPINDLES
(Drosophila
melanogaster) 		5 / 9 ARG A1183
PHE A1200
VAL A1191
LEU A1195
ALA A1197
 None
 1.16A 3unaA-5vjcA:
2.7		 3unaA-5vjcA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNA_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5vjc PROTEIN MINI
SPINDLES
(Drosophila
melanogaster) 		5 / 9 ARG A1183
PHE A1200
VAL A1191
LEU A1195
ALA A1197
 None
 1.15A 3unaB-5vjcA:
undetectable		 3unaB-5vjcA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 5vjc PROTEIN MINI
SPINDLES
(Drosophila
melanogaster) 		4 / 5 LEU A1147
LEU A1148
LEU A1218
SER A1215
 None
 1.01A 3vhuA-5vjcA:
undetectable		 3vhuA-5vjcA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 5vjc PROTEIN MINI
SPINDLES
(Drosophila
melanogaster) 		5 / 12 LEU A1262
LEU A1229
ILE A1232
LEU A1233
ILE A1211
 None
 0.99A 4odrA-5vjcA:
undetectable
4odrB-5vjcA:
undetectable		 4odrA-5vjcA:
17.74
4odrB-5vjcA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CVT_B_ACTB200_0
(N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE)		 5vjc PROTEIN MINI
SPINDLES
(Drosophila
melanogaster) 		3 / 3 ASN A1151
ALA A1189
ARG A1157
 None
 0.49A 5cvtB-5vjcA:
undetectable		 5cvtB-5vjcA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_G_CHDG401_0
(BILE SALT HYDROLASE)		 5vjc PROTEIN MINI
SPINDLES
(Drosophila
melanogaster) 		5 / 10 LEU A1218
TYR A1254
ILE A1211
LEU A1236
LEU A1231
 None
 1.22A 5y7pG-5vjcA:
undetectable		 5y7pG-5vjcA:
22.80