SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vjw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5vjw RHIZOBIALES-LIKE
PHOSPHATASE 2
(Arabidopsis
thaliana) 		3 / 3 ASP A  47
HIS A  81
HIS A  15
 ZN  A 401 (-2.7A)
WO4  A 403 (-4.0A)
ZN  A 402 ( 3.4A)
 0.64A 1oe1A-5vjwA:
undetectable		 1oe1A-5vjwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5vjw RHIZOBIALES-LIKE
PHOSPHATASE 2
(Arabidopsis
thaliana) 		3 / 3 ASP A  47
HIS A  81
HIS A  15
 ZN  A 401 (-2.7A)
WO4  A 403 (-4.0A)
ZN  A 402 ( 3.4A)
 0.63A 1oe3A-5vjwA:
undetectable		 1oe3A-5vjwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_D_FUAD705_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5vjw RHIZOBIALES-LIKE
PHOSPHATASE 2
(Arabidopsis
thaliana) 		5 / 12 SER A 152
PHE A 160
SER A 158
ALA A  84
HIS A  81
 None
None
None
None
WO4  A 403 (-4.0A)
 1.20A 1q23D-5vjwA:
undetectable
1q23E-5vjwA:
undetectable		 1q23D-5vjwA:
13.90
1q23E-5vjwA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 5vjw RHIZOBIALES-LIKE
PHOSPHATASE 2
(Arabidopsis
thaliana) 		5 / 12 LEU A  21
ASN A  22
LEU A  24
VAL A  42
LEU A  65
 None
 1.32A 2q7kA-5vjwA:
undetectable		 2q7kA-5vjwA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1499_1
(CYTOCHROME P450 3A4)		 5vjw RHIZOBIALES-LIKE
PHOSPHATASE 2
(Arabidopsis
thaliana) 		4 / 5 PHE A  88
SER A 179
PHE A 160
ILE A  63
 None
 1.27A 2v0mD-5vjwA:
undetectable		 2v0mD-5vjwA:
10.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_E_GCSE710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 5vjw RHIZOBIALES-LIKE
PHOSPHATASE 2
(Arabidopsis
thaliana) 		4 / 8 ASP A 233
SER A 235
ILE A 236
ASP A  97
 None
 1.01A 2xadA-5vjwA:
undetectable		 2xadA-5vjwA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_F_GCSF710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 5vjw RHIZOBIALES-LIKE
PHOSPHATASE 2
(Arabidopsis
thaliana) 		4 / 8 ASP A 233
SER A 235
ILE A 236
ASP A  97
 None
 1.01A 2xadB-5vjwA:
undetectable		 2xadB-5vjwA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_G_GCSG710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 5vjw RHIZOBIALES-LIKE
PHOSPHATASE 2
(Arabidopsis
thaliana) 		4 / 8 ASP A 233
SER A 235
ILE A 236
ASP A  97
 None
 1.01A 2xadC-5vjwA:
undetectable		 2xadC-5vjwA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_H_GCSH710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 5vjw RHIZOBIALES-LIKE
PHOSPHATASE 2
(Arabidopsis
thaliana) 		4 / 8 ASP A 233
SER A 235
ILE A 236
ASP A  97
 None
 1.03A 2xadD-5vjwA:
undetectable		 2xadD-5vjwA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5vjw RHIZOBIALES-LIKE
PHOSPHATASE 2
(Arabidopsis
thaliana) 		3 / 3 ASP A  47
HIS A  81
HIS A  15
 ZN  A 401 (-2.7A)
WO4  A 403 (-4.0A)
ZN  A 402 ( 3.4A)
 0.67A 2xxgA-5vjwA:
undetectable		 2xxgA-5vjwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1339_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5vjw RHIZOBIALES-LIKE
PHOSPHATASE 2
(Arabidopsis
thaliana) 		3 / 3 ASP A  47
HIS A  81
HIS A  15
 ZN  A 401 (-2.7A)
WO4  A 403 (-4.0A)
ZN  A 402 ( 3.4A)
 0.67A 2xxgC-5vjwA:
undetectable		 2xxgC-5vjwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_1
(CYTOCHROME P450 2R1)		 5vjw RHIZOBIALES-LIKE
PHOSPHATASE 2
(Arabidopsis
thaliana) 		5 / 12 LEU A  28
LEU A  62
ALA A 292
ALA A  40
ILE A  14
 None
 0.95A 3c6gA-5vjwA:
undetectable		 3c6gA-5vjwA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL4_A_ROCA100_2
(PROTEASE)		 5vjw RHIZOBIALES-LIKE
PHOSPHATASE 2
(Arabidopsis
thaliana) 		5 / 9 ILE A  14
GLY A  12
ILE A 279
PRO A 289
THR A 304
 None
 1.24A 3el4B-5vjwA:
undetectable		 3el4B-5vjwA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SOA_A_DB8A445_1
(CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II
SUBUNIT ALPHA WITH A
BETA 7 LINKER)		 5vjw RHIZOBIALES-LIKE
PHOSPHATASE 2
(Arabidopsis
thaliana) 		4 / 6 LEU A 209
VAL A 261
MET A 275
VAL A   8
 None
 1.07A 3soaA-5vjwA:
undetectable		 3soaA-5vjwA:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 5vjw RHIZOBIALES-LIKE
PHOSPHATASE 2
(Arabidopsis
thaliana) 		4 / 6 HIS A  15
HIS A 213
ASP A  60
ASP A  82
 ZN  A 402 ( 3.4A)
ZN  A 401 (-3.4A)
None
None
 1.11A 4blvA-5vjwA:
undetectable		 4blvA-5vjwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA8_C_Z80C301_1
(MAJOR PRION PROTEIN)		 5vjw RHIZOBIALES-LIKE
PHOSPHATASE 2
(Arabidopsis
thaliana) 		4 / 5 GLY A  79
ILE A 239
LYS A 238
GLN A 129
 None
None
WO4  A 404 (-3.5A)
WO4  A 404 ( 4.8A)
 1.05A 4ma8C-5vjwA:
undetectable		 4ma8C-5vjwA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 5vjw RHIZOBIALES-LIKE
PHOSPHATASE 2
(Arabidopsis
thaliana) 		4 / 4 ASN A  80
GLY A  79
ASP A 287
ASP A  50
 WO4  A 403 ( 2.3A)
None
None
None
 1.38A 4n49A-5vjwA:
undetectable		 4n49A-5vjwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5vjw RHIZOBIALES-LIKE
PHOSPHATASE 2
(Arabidopsis
thaliana) 		4 / 5 ILE A 210
ASP A 195
GLU A 192
VAL A  75
 None
 1.24A 4nkxC-5vjwA:
undetectable		 4nkxC-5vjwA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5vjw RHIZOBIALES-LIKE
PHOSPHATASE 2
(Arabidopsis
thaliana) 		4 / 5 ILE A 210
ASP A 195
GLU A 192
VAL A  75
 None
 1.22A 4nkxD-5vjwA:
undetectable		 4nkxD-5vjwA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HP1_A_PPFA602_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 5vjw RHIZOBIALES-LIKE
PHOSPHATASE 2
(Arabidopsis
thaliana) 		4 / 6 ARG A 245
ASP A  13
GLY A 283
ASP A  47
 WO4  A 403 (-2.5A)
ZN  A 402 (-3.1A)
None
ZN  A 401 (-2.7A)
 1.25A 5hp1A-5vjwA:
undetectable		 5hp1A-5vjwA:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HP1_C_PPFC601_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 5vjw RHIZOBIALES-LIKE
PHOSPHATASE 2
(Arabidopsis
thaliana) 		4 / 6 ARG A 245
ASP A  13
GLY A 283
ASP A  47
 WO4  A 403 (-2.5A)
ZN  A 402 (-3.1A)
None
ZN  A 401 (-2.7A)
 1.28A 5hp1C-5vjwA:
undetectable		 5hp1C-5vjwA:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_B_SAMB1304_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 5vjw RHIZOBIALES-LIKE
PHOSPHATASE 2
(Arabidopsis
thaliana) 		3 / 3 ASN A  80
TYR A 154
CYH A  49
 WO4  A 403 ( 2.3A)
WO4  A 404 ( 4.0A)
None
 0.94A 5lsuB-5vjwA:
undetectable		 5lsuB-5vjwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_C_CHDC401_0
(BILE SALT HYDROLASE)		 5vjw RHIZOBIALES-LIKE
PHOSPHATASE 2
(Arabidopsis
thaliana) 		4 / 8 LEU A  92
LEU A  77
ALA A  78
LEU A 242
 None
 0.74A 5y7pC-5vjwA:
undetectable		 5y7pC-5vjwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA609_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 5vjw RHIZOBIALES-LIKE
PHOSPHATASE 2
(Arabidopsis
thaliana) 		3 / 3 HIS A 266
HIS A 267
ARG A 276
 ZN  A 401 ( 3.3A)
None
None
 1.09A 6b58A-5vjwA:
undetectable		 6b58A-5vjwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DEB_B_MTXB302_1
(BIFUNCTIONAL PROTEIN
FOLD)		 5vjw RHIZOBIALES-LIKE
PHOSPHATASE 2
(Arabidopsis
thaliana) 		5 / 12 LEU A  89
THR A  55
ILE A  59
VAL A  58
THR A 159
 None
 1.28A 6debB-5vjwA:
undetectable		 6debB-5vjwA:
17.65