SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vkq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D8C_A_SORA4000_0
(MALATE SYNTHASE G)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
3 / 3 GLN A 761
HIS A 765
PRO A 763
None
0.76A 1d8cA-5vkqA:
undetectable
1d8cA-5vkqA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IA0_B_TXLB502_1
(TUBULIN BETA CHAIN)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
5 / 12 ASP A1142
LEU A1081
PHE A1116
THR A1079
GLY A1110
None
1.28A 1ia0B-5vkqA:
0.0
1ia0B-5vkqA:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R55_A_097A518_1
(ADAM 33)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
5 / 10 ALA A 410
THR A 407
THR A 431
HIS A 395
ALA A 437
None
1.24A 1r55A-5vkqA:
undetectable
1r55A-5vkqA:
8.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUB_B_TXLB501_1
(TUBULIN)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
5 / 12 ASP A1142
LEU A1081
PHE A1116
THR A1079
GLY A1110
None
1.28A 1tubB-5vkqA:
undetectable
1tubB-5vkqA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W0G_A_MYTA1499_1
(CYTOCHROME P450 3A4)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
4 / 6 ILE A 843
ALA A 831
THR A 829
ALA A 864
None
0.97A 1w0gA-5vkqA:
undetectable
1w0gA-5vkqA:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
3 / 3 HIS A 908
ASP A 943
ASN A 989
None
0.87A 1wg8B-5vkqA:
undetectable
1wg8B-5vkqA:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_A_PXLA1003_1
(PYRIDOXINE KINASE)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
4 / 8 VAL A 878
LEU A 882
PRO A 866
HIS A 832
None
1.02A 2ddwA-5vkqA:
undetectable
2ddwA-5vkqA:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_A_BEZA352_0
(D-AMINO-ACID OXIDASE)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
4 / 6 LEU A1016
TYR A1011
ILE A1007
GLY A 971
None
0.91A 2du8A-5vkqA:
undetectable
2du8A-5vkqA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_B_BEZB1352_0
(D-AMINO-ACID OXIDASE)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
4 / 6 LEU A1016
TYR A1011
ILE A1007
GLY A 971
None
0.93A 2du8B-5vkqA:
undetectable
2du8B-5vkqA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDK_A_C2FA1410_0
(GLYCINE
N-METHYLTRANSFERASE)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
5 / 11 LEU A 539
HIS A 540
TYR A 570
LEU A 554
HIS A 553
None
1.44A 2idkA-5vkqA:
undetectable
2idkB-5vkqA:
undetectable
2idkC-5vkqA:
undetectable
2idkD-5vkqA:
undetectable
2idkA-5vkqA:
10.40
2idkB-5vkqA:
10.40
2idkC-5vkqA:
10.40
2idkD-5vkqA:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ERD_A_DESA600_1
(ESTROGEN RECEPTOR
ALPHA)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
5 / 12 LEU A 665
ALA A 667
LEU A 680
LEU A 679
LEU A 712
None
1.18A 3erdA-5vkqA:
undetectable
3erdA-5vkqA:
9.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6V_A_SAMA465_0
(RRNA METHYLASE)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
5 / 12 ALA A 983
GLY A1021
GLY A1020
PRO A1013
LEU A 979
None
1.01A 3m6vA-5vkqA:
undetectable
3m6vA-5vkqA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA270_0
(PROTEIN SSM1)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
4 / 5 LEU A1029
SER A1033
LEU A1014
PRO A1013
None
0.90A 3onnA-5vkqA:
undetectable
3onnA-5vkqA:
9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
4 / 7 LEU A1549
GLN A1551
PHE A1443
LEU A1447
None
0.98A 3x2qP-5vkqA:
6.2
3x2qW-5vkqA:
undetectable
3x2qP-5vkqA:
9.62
3x2qW-5vkqA:
3.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_E_ZPCE1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
4 / 6 GLU A1120
PHE A1116
HIS A1054
VAL A1092
None
1.18A 4a97E-5vkqA:
3.4
4a97E-5vkqA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LA0_B_198B601_1
(SERUM ALBUMIN)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
5 / 9 LEU A1185
ALA A1118
PHE A1145
PHE A1164
LEU A1178
None
1.48A 4la0B-5vkqA:
4.6
4la0B-5vkqA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_2
(TUBULIN BETA CHAIN)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
5 / 12 LEU A 454
ALA A 437
VAL A 427
ALA A 458
ILE A 405
None
1.13A 4x1kD-5vkqA:
undetectable
4x1kD-5vkqA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_B_DESB600_1
(ESTROGEN RECEPTOR)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
5 / 11 LEU A 665
ALA A 667
LEU A 680
LEU A 679
LEU A 712
None
1.23A 4zn7B-5vkqA:
undetectable
4zn7B-5vkqA:
10.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_3
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
5 / 12 PHE A1234
VAL A1246
ILE A1247
LEU A1259
ILE A1580
None
1.23A 5b8iC-5vkqA:
undetectable
5b8iC-5vkqA:
5.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
4 / 6 PHE A1116
SER A1105
ALA A1112
LEU A1081
None
1.00A 5dzkB-5vkqA:
undetectable
5dzkP-5vkqA:
undetectable
5dzkB-5vkqA:
8.08
5dzkP-5vkqA:
1.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_U_BEZU801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
4 / 6 PHE A1116
SER A1105
ALA A1112
LEU A1081
None
1.03A 5dzkg-5vkqA:
undetectable
5dzku-5vkqA:
undetectable
5dzkg-5vkqA:
8.08
5dzku-5vkqA:
1.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPU_A_IPHA101_0
(INSULIN, CHAIN A
INSULIN, CHAIN B)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
4 / 4 CYH A1097
LEU A1129
LEU A1081
ALA A1085
None
0.98A 5hpuA-5vkqA:
undetectable
5hpuB-5vkqA:
undetectable
5hpuA-5vkqA:
3.06
5hpuB-5vkqA:
1.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_F_SC2F1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
3 / 3 VAL A 842
GLN A 802
CYH A 830
None
0.82A 5icxC-5vkqA:
undetectable
5icxF-5vkqA:
undetectable
5icxC-5vkqA:
8.76
5icxF-5vkqA:
0.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
4 / 5 PRO A1080
HIS A1056
LEU A1036
TYR A1011
None
1.49A 5igjA-5vkqA:
undetectable
5igjA-5vkqA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ITZ_B_LOCB502_1
(TUBULIN BETA-2B
CHAIN)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
5 / 12 LEU A 981
LEU A 979
ALA A 983
LEU A1016
ILE A1007
None
1.11A 5itzB-5vkqA:
undetectable
5itzB-5vkqA:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JI0_D_BRLD501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
5 / 12 GLY A1067
HIS A1049
LEU A1014
MET A1059
LEU A1096
None
1.31A 5ji0D-5vkqA:
undetectable
5ji0D-5vkqA:
9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_A_Z80A401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
5 / 11 ILE A 797
PHE A 812
VAL A 842
ASN A 803
ALA A 768
None
0.95A 5lg3A-5vkqA:
3.4
5lg3A-5vkqA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_E_Z80E401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
5 / 12 ILE A 797
PHE A 812
VAL A 842
ASN A 803
ALA A 768
None
0.99A 5lg3E-5vkqA:
undetectable
5lg3E-5vkqA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_G_ACTG702_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
3 / 3 GLY A 827
THR A 829
ASN A 859
None
0.59A 5odiG-5vkqA:
undetectable
5odiG-5vkqA:
17.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VKQ_A_PCFA1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
5 / 6 ILE A1271
ILE A1416
LEU A1420
PHE A1422
HIS A1423
PCF  A1801 ( 4.6A)
PCF  A1801 ( 4.8A)
PCF  A1801 (-4.7A)
PCF  A1801 (-3.8A)
PCF  A1801 (-2.7A)
0.00A 5vkqA-5vkqA:
51.0
5vkqB-5vkqA:
50.2
5vkqA-5vkqA:
100.00
5vkqB-5vkqA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VKQ_A_PCFA1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
4 / 6 ILE A1301
ILE A1416
LEU A1420
HIS A1423
None
PCF  A1801 ( 4.8A)
PCF  A1801 (-4.7A)
PCF  A1801 (-2.7A)
0.81A 5vkqA-5vkqA:
51.0
5vkqB-5vkqA:
50.2
5vkqA-5vkqA:
100.00
5vkqB-5vkqA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VKQ_A_PCFA1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
6 / 10 TYR A1528
TYR A1532
LYS A1535
ILE A1536
ILE A1540
LEU A1543
PCF  A1803 (-4.5A)
PCF  A1803 (-2.6A)
PCF  A1803 (-4.6A)
PCF  A1803 (-4.6A)
PCF  A1803 ( 4.7A)
PCF  A1803 ( 4.8A)
0.00A 5vkqA-5vkqA:
51.0
5vkqD-5vkqA:
48.5
5vkqA-5vkqA:
100.00
5vkqD-5vkqA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VKQ_A_PCFA1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
5 / 7 PHE A1486
VAL A1489
HIS A1492
PRO A1493
ILE A1494
PCF  A1805 (-3.2A)
PCF  A1805 (-3.8A)
PCF  A1805 ( 3.8A)
PCF  A1805 (-4.0A)
PCF  A1805 ( 4.5A)
0.00A 5vkqA-5vkqA:
49.7
5vkqD-5vkqA:
48.5
5vkqA-5vkqA:
100.00
5vkqD-5vkqA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VKQ_A_PCFA1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
4 / 5 LEU A1437
LYS A1438
ALA A1441
LEU A1444
PCF  A1808 ( 3.3A)
PCF  A1808 (-4.2A)
PCF  A1808 (-3.2A)
PCF  A1808 (-4.9A)
0.15A 5vkqA-5vkqA:
49.7
5vkqD-5vkqA:
48.5
5vkqA-5vkqA:
100.00
5vkqD-5vkqA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VKQ_B_PCFB1802_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
5 / 7 PHE A1486
VAL A1489
HIS A1492
PRO A1493
ILE A1494
PCF  A1805 (-3.2A)
PCF  A1805 (-3.8A)
PCF  A1805 ( 3.8A)
PCF  A1805 (-4.0A)
PCF  A1805 ( 4.5A)
0.00A 5vkqA-5vkqA:
49.7
5vkqB-5vkqA:
48.6
5vkqA-5vkqA:
100.00
5vkqB-5vkqA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VKQ_B_PCFB1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
4 / 5 LEU A1437
LYS A1438
ALA A1441
LEU A1444
PCF  A1808 ( 3.3A)
PCF  A1808 (-4.2A)
PCF  A1808 (-3.2A)
PCF  A1808 (-4.9A)
0.00A 5vkqA-5vkqA:
49.7
5vkqB-5vkqA:
48.6
5vkqA-5vkqA:
100.00
5vkqB-5vkqA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VKQ_B_PCFB1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
6 / 10 TYR A1528
TYR A1532
LYS A1535
ILE A1536
ILE A1540
LEU A1543
PCF  A1803 (-4.5A)
PCF  A1803 (-2.6A)
PCF  A1803 (-4.6A)
PCF  A1803 (-4.6A)
PCF  A1803 ( 4.7A)
PCF  A1803 ( 4.8A)
0.09A 5vkqA-5vkqA:
51.0
5vkqB-5vkqA:
50.2
5vkqA-5vkqA:
100.00
5vkqB-5vkqA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VKQ_C_PCFC1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
6 / 9 TYR A1528
TYR A1532
LYS A1535
ILE A1536
ILE A1540
LEU A1543
PCF  A1803 (-4.5A)
PCF  A1803 (-2.6A)
PCF  A1803 (-4.6A)
PCF  A1803 (-4.6A)
PCF  A1803 ( 4.7A)
PCF  A1803 ( 4.8A)
0.00A 5vkqB-5vkqA:
48.6
5vkqC-5vkqA:
48.6
5vkqB-5vkqA:
100.00
5vkqC-5vkqA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VKQ_C_PCFC1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
6 / 8 PHE A1452
PHE A1486
VAL A1489
HIS A1492
PRO A1493
ILE A1494
None
PCF  A1805 (-3.2A)
PCF  A1805 (-3.8A)
PCF  A1805 ( 3.8A)
PCF  A1805 (-4.0A)
PCF  A1805 ( 4.5A)
0.00A 5vkqB-5vkqA:
48.6
5vkqC-5vkqA:
48.6
5vkqB-5vkqA:
100.00
5vkqC-5vkqA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VKQ_C_PCFC1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
7 / 9 GLY A1363
LEU A1364
LEU A1410
VAL A1414
ILE A1433
GLY A1434
LEU A1437
PCF  A1807 (-3.2A)
PCF  A1807 (-4.7A)
None
None
PCF  A1807 (-3.2A)
PCF  A1807 (-2.4A)
PCF  A1808 ( 3.3A)
0.28A 5vkqC-5vkqA:
48.6
5vkqD-5vkqA:
48.5
5vkqC-5vkqA:
100.00
5vkqD-5vkqA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VKQ_C_PCFC1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
4 / 5 LEU A1437
LYS A1438
ALA A1441
LEU A1444
PCF  A1808 ( 3.3A)
PCF  A1808 (-4.2A)
PCF  A1808 (-3.2A)
PCF  A1808 (-4.9A)
0.12A 5vkqB-5vkqA:
48.6
5vkqC-5vkqA:
48.6
5vkqB-5vkqA:
100.00
5vkqC-5vkqA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VKQ_D_PCFD1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
6 / 10 TYR A1528
TYR A1532
LYS A1535
ILE A1536
ILE A1540
LEU A1543
PCF  A1803 (-4.5A)
PCF  A1803 (-2.6A)
PCF  A1803 (-4.6A)
PCF  A1803 (-4.6A)
PCF  A1803 ( 4.7A)
PCF  A1803 ( 4.8A)
0.10A 5vkqC-5vkqA:
50.2
5vkqD-5vkqA:
48.5
5vkqC-5vkqA:
100.00
5vkqD-5vkqA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VKQ_D_PCFD1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
5 / 7 PHE A1486
VAL A1489
HIS A1492
PRO A1493
ILE A1494
PCF  A1805 (-3.2A)
PCF  A1805 (-3.8A)
PCF  A1805 ( 3.8A)
PCF  A1805 (-4.0A)
PCF  A1805 ( 4.5A)
0.16A 5vkqC-5vkqA:
48.6
5vkqD-5vkqA:
48.5
5vkqC-5vkqA:
100.00
5vkqD-5vkqA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VKQ_D_PCFD1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
4 / 5 LEU A1437
LYS A1438
ALA A1441
LEU A1444
PCF  A1808 ( 3.3A)
PCF  A1808 (-4.2A)
PCF  A1808 (-3.2A)
PCF  A1808 (-4.9A)
0.00A 5vkqC-5vkqA:
48.6
5vkqD-5vkqA:
48.5
5vkqC-5vkqA:
100.00
5vkqD-5vkqA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VKQ_D_PCFD1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
5 / 6 ILE A1271
ILE A1416
LEU A1420
PHE A1422
HIS A1423
PCF  A1801 ( 4.6A)
PCF  A1801 ( 4.8A)
PCF  A1801 (-4.7A)
PCF  A1801 (-3.8A)
PCF  A1801 (-2.7A)
0.00A 5vkqA-5vkqA:
51.0
5vkqD-5vkqA:
48.5
5vkqA-5vkqA:
100.00
5vkqD-5vkqA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VKQ_D_PCFD1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
4 / 6 ILE A1301
ILE A1416
LEU A1420
HIS A1423
None
PCF  A1801 ( 4.8A)
PCF  A1801 (-4.7A)
PCF  A1801 (-2.7A)
0.82A 5vkqA-5vkqA:
51.0
5vkqD-5vkqA:
48.5
5vkqA-5vkqA:
100.00
5vkqD-5vkqA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
4 / 7 LEU A1549
GLN A1551
PHE A1443
LEU A1447
None
0.97A 5zcqC-5vkqA:
6.2
5zcqJ-5vkqA:
undetectable
5zcqC-5vkqA:
9.62
5zcqJ-5vkqA:
3.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JMJ_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
4 / 5 GLY A1077
THR A1073
HIS A1082
SER A1102
None
1.12A 6jmjA-5vkqA:
undetectable
6jmjA-5vkqA:
6.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
4 / 6 GLY A1077
THR A1073
HIS A1082
SER A1102
None
1.10A 6jogA-5vkqA:
undetectable
6jogA-5vkqA:
6.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster)
4 / 6 THR A1309
LEU A1308
THR A1289
LEU A1274
None
1.19A 6mvxA-5vkqA:
7.2
6mvxB-5vkqA:
5.3
6mvxC-5vkqA:
7.7
6mvxA-5vkqA:
9.77
6mvxB-5vkqA:
9.77
6mvxC-5vkqA:
9.77