SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vkv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_A_ASDA1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 5vkv CYTOCHROME C-TYPE
BIOGENESIS PROTEIN
CCDA
(Thermus
thermophilus) 		4 / 8 ILE A 128
GLY A 129
LEU A 136
PHE A  54
 None
 0.83A 2vctA-5vkvA:
undetectable		 2vctA-5vkvA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_B_ASDB1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 5vkv CYTOCHROME C-TYPE
BIOGENESIS PROTEIN
CCDA
(Thermus
thermophilus) 		4 / 8 ILE A 128
GLY A 129
LEU A 136
PHE A  54
 None
 0.83A 2vctB-5vkvA:
undetectable		 2vctB-5vkvA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_D_ASDD1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 5vkv CYTOCHROME C-TYPE
BIOGENESIS PROTEIN
CCDA
(Thermus
thermophilus) 		4 / 7 ILE A 128
GLY A 129
LEU A 136
PHE A  54
 None
 0.85A 2vctD-5vkvA:
undetectable		 2vctD-5vkvA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5vkv CYTOCHROME C-TYPE
BIOGENESIS PROTEIN
CCDA
(Thermus
thermophilus) 		5 / 12 ALA A 166
PHE A  54
TYR A 151
PHE A  50
PHE A  16
 None
 1.23A 5jlcA-5vkvA:
undetectable		 5jlcA-5vkvA:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5vkv CYTOCHROME C-TYPE
BIOGENESIS PROTEIN
CCDA
(Thermus
thermophilus) 		5 / 12 PHE A  54
TYR A 151
PHE A  50
THR A 125
PHE A  16
 None
 1.30A 5jlcA-5vkvA:
undetectable		 5jlcA-5vkvA:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA406_0
(THIOREDOXIN
REDUCTASE)		 5vkv CYTOCHROME C-TYPE
BIOGENESIS PROTEIN
CCDA
(Thermus
thermophilus) 		3 / 3 HIS A 181
SER A 180
ARG A 174
 None
 0.91A 5u63A-5vkvA:
undetectable		 5u63A-5vkvA:
undetectable