SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vl3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5vl3 B-CELL RECEPTOR CD22
(Homo
sapiens) 		4 / 7 LEU Q 163
GLN Q 164
PHE Q 199
LEU Q 174
 None
 1.09A 1v55C-5vl3Q:
undetectable
1v55J-5vl3Q:
undetectable		 1v55C-5vl3Q:
21.85
1v55J-5vl3Q:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5vl3 B-CELL RECEPTOR CD22
(Homo
sapiens) 		4 / 7 LEU Q 163
GLN Q 164
PHE Q 199
LEU Q 174
 None
 1.08A 2dysP-5vl3Q:
undetectable
2dysW-5vl3Q:
undetectable		 2dysP-5vl3Q:
21.85
2dysW-5vl3Q:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5vl3 B-CELL RECEPTOR CD22
(Homo
sapiens) 		4 / 7 LEU Q 163
GLN Q 164
PHE Q 199
LEU Q 174
 None
 1.07A 2eijC-5vl3Q:
undetectable
2eijJ-5vl3Q:
undetectable		 2eijC-5vl3Q:
21.85
2eijJ-5vl3Q:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5vl3 B-CELL RECEPTOR CD22
(Homo
sapiens) 		4 / 7 LEU Q 163
GLN Q 164
PHE Q 199
LEU Q 174
 None
 1.09A 2eimC-5vl3Q:
undetectable
2eimJ-5vl3Q:
undetectable		 2eimC-5vl3Q:
21.85
2eimJ-5vl3Q:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5vl3 B-CELL RECEPTOR CD22
(Homo
sapiens) 		4 / 6 LEU Q 163
GLN Q 164
PHE Q 199
LEU Q 174
 None
 1.10A 2einP-5vl3Q:
undetectable
2einW-5vl3Q:
undetectable		 2einP-5vl3Q:
21.85
2einW-5vl3Q:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 5vl3 B-CELL RECEPTOR CD22
(Homo
sapiens) 		4 / 6 GLY Q  96
TYR Q  77
ASP Q  97
ASN Q 101
 NAG  Q1003 ( 4.8A)
None
None
NAG  Q1003 (-1.9A)
 1.15A 2g72A-5vl3Q:
undetectable		 2g72A-5vl3Q:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5vl3 B-CELL RECEPTOR CD22
(Homo
sapiens) 		4 / 6 LEU Q 163
GLN Q 164
PHE Q 199
LEU Q 174
 None
 1.01A 3ag1C-5vl3Q:
undetectable
3ag1J-5vl3Q:
undetectable		 3ag1C-5vl3Q:
21.85
3ag1J-5vl3Q:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ITA_D_AICD501_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC)		 5vl3 B-CELL RECEPTOR CD22
(Homo
sapiens) 		3 / 3 PRO Q 140
PHE Q 165
ALA Q  38
 None
 0.44A 3itaD-5vl3Q:
undetectable		 3itaD-5vl3Q:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5vl3 B-CELL RECEPTOR CD22
(Homo
sapiens) 		4 / 6 PHE Q 206
LEU Q 178
VAL Q 217
VAL Q 238
 None
 1.08A 4l4cA-5vl3Q:
undetectable		 4l4cA-5vl3Q:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_B_1FLB1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 5vl3 B-CELL RECEPTOR CD22
(Homo
sapiens) 		5 / 9 LEU Q 193
THR Q 191
ILE Q 172
PRO Q 143
LEU Q 174
 None
 1.28A 5g48B-5vl3Q:
undetectable		 5g48B-5vl3Q:
22.22