SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vlh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1J3J_A_CP6A609_1 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 10	ALA A 388 SER A 419 ILE A 416 ILE A 334 THR A 385	None	1.20A	1j3jA-5vlhA: undetectable	1j3jA-5vlhA: 17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1J8U_A_H4BA429_1 (PHENYLALANINE-4-HYDR OXYLASE)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	4 / 7	LEU A 348 LEU A 351 PHE A 318 ALA A 315	None	0.66A	1j8uA-5vlhA: undetectable	1j8uA-5vlhA: 19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KIA_D_SAMD3293_0 (GLYCINE N-METHYLTRANSFERASE)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 12	GLY A 316 ASP A 320 ALA A 388 SER A 386 LEU A 361	None	1.36A	1kiaD-5vlhA: undetectable	1kiaD-5vlhA: 21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJ2_A_SAMA2201_1 (PROTEIN (METHIONINE REPRESSOR))	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	4 / 4	HIS A 391 ALA A 363 PHE A 362 GLY A 365	None	1.28A	1mj2B-5vlhA: undetectable	1mj2B-5vlhA: 14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJ2_C_SAMC1200_1 (PROTEIN (METHIONINE REPRESSOR))	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	4 / 4	HIS A 391 ALA A 363 PHE A 362 GLY A 365	None	1.28A	1mj2D-5vlhA: undetectable	1mj2D-5vlhA: 14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJO_A_SAMA199_1 (METHIONINE REPRESSOR)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	4 / 4	HIS A 391 ALA A 363 PHE A 362 GLY A 365	None	1.26A	1mjoB-5vlhA: undetectable	1mjoB-5vlhA: 14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJO_B_SAMB200_0 (METHIONINE REPRESSOR)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	4 / 4	HIS A 391 ALA A 363 PHE A 362 GLY A 365	None	1.21A	1mjoA-5vlhA: undetectable	1mjoA-5vlhA: 14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJO_D_SAMD200_1 (METHIONINE REPRESSOR)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	4 / 4	HIS A 391 ALA A 363 PHE A 362 GLY A 365	None	1.27A	1mjoD-5vlhA: undetectable	1mjoD-5vlhA: 14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RQP_B_SAMB500_1 (5'-FLUORO-5'-DEOXYAD ENOSINE SYNTHASE)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	4 / 8	PHE A 318 ASN A 354 SER A 386 ALA A 322	None	1.08A	1rqpC-5vlhA: 5.5	1rqpC-5vlhA: 22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RQP_C_SAMC500_0 (5'-FLUORO-5'-DEOXYAD ENOSINE SYNTHASE)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	4 / 8	PHE A 318 ASN A 354 SER A 386 ALA A 322	None	1.09A	1rqpA-5vlhA: 5.4	1rqpA-5vlhA: 22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZLQ_A_ACTA1507_0 (NICKEL-BINDING PERIPLASMIC PROTEIN)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	3 / 3	GLN A 190 HIS A 193 ARG A 194	None	1.10A	1zlqA-5vlhA: 0.1	1zlqA-5vlhA: 23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DDW_A_PXLA1003_1 (PYRIDOXINE KINASE)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	4 / 8	VAL A 312 VAL A 336 LEU A 286 HIS A 391	None	1.00A	2ddwA-5vlhA: 4.6	2ddwA-5vlhA: 23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2UVN_B_ECNB1406_1 (CYTOCHROME P450 130)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 11	ASP A 343 PRO A 345 THR A 353 GLY A 337 VAL A 441	None	1.46A	2uvnB-5vlhA: undetectable	2uvnB-5vlhA: 24.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V7U_A_SAMA1299_0 (5'-FLUORO-5'-DEOXY ADENOSINE SYNTHETASE)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	4 / 8	PHE A 318 ASN A 354 SER A 386 ALA A 322	None	1.10A	2v7uA-5vlhA: 5.3	2v7uA-5vlhA: 23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GCS_A_BAXA401_2 (MITOGEN-ACTIVATED PROTEIN KINASE 14)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	4 / 6	VAL A 336 LEU A 436 ILE A 395 ILE A 334	None	0.87A	3gcsA-5vlhA: undetectable	3gcsA-5vlhA: 22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KEE_A_30BA500_1 (GENOME POLYPROTEIN)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 12	HIS A 226 ASP A 186 GLY A 384 SER A 386 ALA A 290	None	0.93A	3keeA-5vlhA: undetectable	3keeA-5vlhA: 17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KEE_B_30BB500_1 (GENOME POLYPROTEIN)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 12	GLN A 382 HIS A 226 ASP A 186 GLY A 384 ALA A 290	None	0.95A	3keeB-5vlhA: undetectable	3keeB-5vlhA: 17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KEE_B_30BB500_1 (GENOME POLYPROTEIN)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 12	GLN A 382 HIS A 226 ASP A 186 GLY A 384 SER A 386	None	0.87A	3keeB-5vlhA: undetectable	3keeB-5vlhA: 17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KEE_C_30BC500_2 (GENOME POLYPROTEIN)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	4 / 4	GLN A 433 PHE A 355 TYR A 325 LEU A 440	None	1.40A	3keeC-5vlhA: undetectable	3keeC-5vlhA: 17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KEE_D_30BD500_1 (GENOME POLYPROTEIN)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	6 / 12	GLN A 382 HIS A 226 ASP A 186 GLY A 384 SER A 386 ALA A 290	None	1.14A	3keeD-5vlhA: undetectable	3keeD-5vlhA: 17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KU1_G_SAMG226_0 (SAM-DEPENDENT METHYLTRANSFERASE)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 12	VAL A 284 PRO A 282 ALA A 409 LEU A 415 ILE A 334	None	0.75A	3ku1G-5vlhA: undetectable	3ku1G-5vlhA: 20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KU1_H_SAMH226_0 (SAM-DEPENDENT METHYLTRANSFERASE)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 12	VAL A 284 PRO A 282 ALA A 409 LEU A 415 ILE A 334	None	0.73A	3ku1H-5vlhA: undetectable	3ku1H-5vlhA: 20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LBD_A_9CRA424_1 (RETINOIC ACID RECEPTOR GAMMA)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 12	ALA A 338 ILE A 424 PHE A 429 GLY A 356 ALA A 322	None	1.07A	3lbdA-5vlhA: undetectable	3lbdA-5vlhA: 19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OGP_B_017B200_2 (FIV PROTEASE)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 9	GLY A 394 ALA A 393 ILE A 334 ILE A 368 LEU A 286	None	1.01A	3ogpB-5vlhA: undetectable	3ogpB-5vlhA: 13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SUD_A_SUEA1201_1 (NS3 PROTEASE, NS4A PROTEIN)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 12	GLN A 382 HIS A 226 ASP A 186 GLY A 384 ALA A 290	None	1.01A	3sudA-5vlhA: undetectable	3sudA-5vlhA: 19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SUE_A_SUEA1201_1 (NS3 PROTEASE, NS4A PROTEIN)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 12	GLN A 382 HIS A 226 ASP A 186 GLY A 384 SER A 386	None	0.93A	3sueA-5vlhA: undetectable	3sueA-5vlhA: 19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SUE_A_SUEA1201_1 (NS3 PROTEASE, NS4A PROTEIN)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 12	HIS A 226 ASP A 186 GLY A 384 SER A 386 ALA A 290	None	0.96A	3sueA-5vlhA: undetectable	3sueA-5vlhA: 19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SUE_B_SUEB1201_1 (NS3 PROTEASE, NS4A PROTEIN)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 12	GLN A 382 HIS A 226 ASP A 186 GLY A 384 ALA A 290	None	1.10A	3sueB-5vlhA: undetectable	3sueB-5vlhA: 19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SUE_B_SUEB1201_1 (NS3 PROTEASE, NS4A PROTEIN)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 12	GLN A 382 HIS A 226 ASP A 186 GLY A 384 SER A 386	None	0.93A	3sueB-5vlhA: undetectable	3sueB-5vlhA: 19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SUE_C_SUEC1201_1 (NS3 PROTEASE, NS4A PROTEIN)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 12	GLN A 382 HIS A 226 ASP A 186 GLY A 384 SER A 386	None	0.93A	3sueC-5vlhA: undetectable	3sueC-5vlhA: 19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SUE_C_SUEC1201_1 (NS3 PROTEASE, NS4A PROTEIN)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 12	HIS A 226 ASP A 186 GLY A 384 SER A 386 ALA A 290	None	0.98A	3sueC-5vlhA: undetectable	3sueC-5vlhA: 19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SUE_D_SUED1201_1 (NS3 PROTEASE, NS4A PROTEIN)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 12	GLN A 382 HIS A 226 ASP A 186 GLY A 384 SER A 386	None	0.89A	3sueD-5vlhA: undetectable	3sueD-5vlhA: 19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SUF_A_SUEA1201_1 (NS3 PROTEASE, NS4A PROTEIN)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 12	GLN A 382 HIS A 226 ASP A 186 GLY A 384 ALA A 290	None	0.90A	3sufA-5vlhA: undetectable	3sufA-5vlhA: 19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SUF_A_SUEA1201_1 (NS3 PROTEASE, NS4A PROTEIN)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 12	GLN A 382 HIS A 226 ASP A 186 GLY A 384 SER A 386	None	0.86A	3sufA-5vlhA: undetectable	3sufA-5vlhA: 19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SUF_B_SUEB1201_1 (NS3 PROTEASE, NS4A PROTEIN)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 12	GLN A 382 HIS A 226 ASP A 186 GLY A 384 SER A 386	None	1.00A	3sufB-5vlhA: undetectable	3sufB-5vlhA: 19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SUF_B_SUEB1201_1 (NS3 PROTEASE, NS4A PROTEIN)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 12	HIS A 226 ASP A 186 GLY A 384 SER A 386 ALA A 290	None	0.98A	3sufB-5vlhA: undetectable	3sufB-5vlhA: 19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SUF_C_SUEC1201_1 (NS3 PROTEASE, NS4A PROTEIN)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 11	GLN A 382 HIS A 226 ASP A 186 GLY A 384 SER A 386	None	0.89A	3sufC-5vlhA: undetectable	3sufC-5vlhA: 19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SUF_C_SUEC1201_1 (NS3 PROTEASE, NS4A PROTEIN)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 11	HIS A 226 ASP A 186 GLY A 384 SER A 386 ALA A 290	None	0.97A	3sufC-5vlhA: undetectable	3sufC-5vlhA: 19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L1A_A_AB1A101_2 (MDR769 HIV-1 PROTEASE)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	4 / 6	ASP A 360 GLY A 356 PRO A 345 THR A 339	CA A 501 (-2.5A) None None None	1.11A	4l1aB-5vlhA: undetectable	4l1aB-5vlhA: 15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVL_K_BO2K301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 11	ALA A 397 ALA A 393 GLY A 176 GLY A 244 ALA A 245	None	1.03A	4qvlK-5vlhA: undetectable 4qvlL-5vlhA: undetectable	4qvlK-5vlhA: 18.52 4qvlL-5vlhA: 21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVL_Y_BO2Y301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 11	ALA A 397 ALA A 393 GLY A 176 GLY A 244 ALA A 245	None	1.03A	4qvlY-5vlhA: undetectable 4qvlZ-5vlhA: undetectable	4qvlY-5vlhA: 18.52 4qvlZ-5vlhA: 21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVM_K_BO2K301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 9	ALA A 397 ALA A 393 GLY A 176 GLY A 244 ALA A 245	None	1.03A	4qvmK-5vlhA: undetectable 4qvmL-5vlhA: undetectable	4qvmK-5vlhA: 18.46 4qvmL-5vlhA: 21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVM_Y_BO2Y301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 10	ALA A 397 ALA A 393 GLY A 176 GLY A 244 ALA A 245	None	1.03A	4qvmY-5vlhA: undetectable 4qvmZ-5vlhA: undetectable	4qvmY-5vlhA: 18.46 4qvmZ-5vlhA: 21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVP_K_BO2K301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 10	ALA A 397 ALA A 393 GLY A 176 GLY A 244 ALA A 245	None	1.02A	4qvpK-5vlhA: undetectable 4qvpL-5vlhA: undetectable	4qvpK-5vlhA: 18.90 4qvpL-5vlhA: 21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVP_Y_BO2Y301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 10	ALA A 397 ALA A 393 GLY A 176 GLY A 244 ALA A 245	None	1.02A	4qvpY-5vlhA: undetectable 4qvpZ-5vlhA: undetectable	4qvpY-5vlhA: 18.90 4qvpZ-5vlhA: 21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QW1_K_BO2K301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 11	ALA A 397 ALA A 393 GLY A 176 GLY A 244 ALA A 245	None	1.00A	4qw1K-5vlhA: undetectable 4qw1L-5vlhA: undetectable	4qw1K-5vlhA: 18.74 4qw1L-5vlhA: 21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QW1_Y_BO2Y301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 10	ALA A 397 ALA A 393 GLY A 176 GLY A 244 ALA A 245	None	1.00A	4qw1Y-5vlhA: undetectable 4qw1Z-5vlhA: undetectable	4qw1Y-5vlhA: 18.74 4qw1Z-5vlhA: 21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QW3_K_BO2K301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 10	ALA A 397 ALA A 393 GLY A 176 GLY A 244 ALA A 245	None	1.02A	4qw3K-5vlhA: undetectable 4qw3L-5vlhA: undetectable	4qw3K-5vlhA: 18.46 4qw3L-5vlhA: 21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QW3_Y_BO2Y301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 10	ALA A 397 ALA A 393 GLY A 176 GLY A 244 ALA A 245	None	1.02A	4qw3Y-5vlhA: undetectable 4qw3Z-5vlhA: undetectable	4qw3Y-5vlhA: 18.46 4qw3Z-5vlhA: 21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BXN_K_BO2K301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 11	ALA A 397 ALA A 393 GLY A 176 GLY A 244 ALA A 245	None	1.02A	5bxnK-5vlhA: undetectable 5bxnL-5vlhA: undetectable	5bxnK-5vlhA: 18.52 5bxnL-5vlhA: 21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BXN_Y_BO2Y301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 11	ALA A 397 ALA A 393 GLY A 176 GLY A 244 ALA A 245	None	1.03A	5bxnY-5vlhA: undetectable 5bxnZ-5vlhA: undetectable	5bxnY-5vlhA: 18.52 5bxnZ-5vlhA: 21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5D0X_K_BO2K301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	6 / 9	SER A 401 ALA A 397 ALA A 393 GLY A 176 GLY A 244 ALA A 245	None	1.27A	5d0xK-5vlhA: undetectable 5d0xL-5vlhA: undetectable	5d0xK-5vlhA: 18.52 5d0xL-5vlhA: 21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5D0X_Y_BO2Y301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	6 / 9	SER A 401 ALA A 397 ALA A 393 GLY A 176 GLY A 244 ALA A 245	None	1.24A	5d0xY-5vlhA: undetectable 5d0xZ-5vlhA: undetectable	5d0xY-5vlhA: 18.52 5d0xZ-5vlhA: 21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEV_L_TRPL101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	4 / 8	THR A 437 GLY A 337 ALA A 322 THR A 353	None	0.97A	5eevL-5vlhA: undetectable 5eevV-5vlhA: undetectable	5eevL-5vlhA: 9.83 5eevV-5vlhA: 9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EEW_L_TRPL101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	4 / 8	THR A 437 GLY A 337 ALA A 322 THR A 353	None	0.97A	5eewL-5vlhA: undetectable 5eewV-5vlhA: undetectable	5eewL-5vlhA: 9.83 5eewV-5vlhA: 9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EF3_L_TRPL101_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	4 / 8	THR A 437 GLY A 337 ALA A 322 THR A 353	None	0.96A	5ef3L-5vlhA: undetectable 5ef3V-5vlhA: undetectable	5ef3L-5vlhA: 9.83 5ef3V-5vlhA: 9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6C2M_C_SUEC1203_0 (NS3 PROTEASE)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	6 / 12	GLN A 382 HIS A 226 ASP A 186 GLY A 384 SER A 386 ALA A 290	None	1.14A	6c2mC-5vlhA: undetectable	6c2mC-5vlhA: 11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CE2_B_SVRB202_2 (-)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 12	LEU A 304 LEU A 118 GLY A 267 GLY A 263 ASN A 298	None	1.13A	6ce2B-5vlhA: undetectable	6ce2B-5vlhA: 14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CLX_A_SAMA401_0 (O-METHYLTRANSFERASE)	5vlh	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 12	ASP A 129 ALA A 134 GLY A 76 GLY A 128 VAL A 124	None	1.28A	6clxA-5vlhA: undetectable	6clxA-5vlhA: 23.49

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1J3J_A_CP6A609_1","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"ALA A 388;SER A 419;ILE A 416;ILE A 334;THR A 385","None","1.20A","1j3jA-5vlhA:undetectable","1j3jA-5vlhA:17.06"],["1J8U_A_H4BA429_1","PHENYLALANINE-4-HYDROXYLASE","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",4,"LEU A 348;LEU A 351;PHE A 318;ALA A 315","None","0.66A","1j8uA-5vlhA:undetectable","1j8uA-5vlhA:19.59"],["1KIA_D_SAMD3293_0","GLYCINE N-METHYLTRANSFERASE","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"GLY A 316;ASP A 320;ALA A 388;SER A 386;LEU A 361","None","1.36A","1kiaD-5vlhA:undetectable","1kiaD-5vlhA:21.67"],["1MJ2_A_SAMA2201_1","PROTEIN (METHIONINE REPRESSOR)","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",4,"HIS A 391;ALA A 363;PHE A 362;GLY A 365","None","1.28A","1mj2B-5vlhA:undetectable","1mj2B-5vlhA:14.22"],["1MJ2_C_SAMC1200_1","PROTEIN (METHIONINE REPRESSOR)","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",4,"HIS A 391;ALA A 363;PHE A 362;GLY A 365","None","1.28A","1mj2D-5vlhA:undetectable","1mj2D-5vlhA:14.22"],["1MJO_A_SAMA199_1","METHIONINE REPRESSOR","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",4,"HIS A 391;ALA A 363;PHE A 362;GLY A 365","None","1.26A","1mjoB-5vlhA:undetectable","1mjoB-5vlhA:14.22"],["1MJO_B_SAMB200_0","METHIONINE REPRESSOR","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",4,"HIS A 391;ALA A 363;PHE A 362;GLY A 365","None","1.21A","1mjoA-5vlhA:undetectable","1mjoA-5vlhA:14.22"],["1MJO_D_SAMD200_1","METHIONINE REPRESSOR","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",4,"HIS A 391;ALA A 363;PHE A 362;GLY A 365","None","1.27A","1mjoD-5vlhA:undetectable","1mjoD-5vlhA:14.22"],["1RQP_B_SAMB500_1","5'-FLUORO-5'-DEOXYADENOSINE SYNTHASE","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",4,"PHE A 318;ASN A 354;SER A 386;ALA A 322","None","1.08A","1rqpC-5vlhA:5.5","1rqpC-5vlhA:22.10"],["1RQP_C_SAMC500_0","5'-FLUORO-5'-DEOXYADENOSINE SYNTHASE","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",4,"PHE A 318;ASN A 354;SER A 386;ALA A 322","None","1.09A","1rqpA-5vlhA:5.4","1rqpA-5vlhA:22.10"],["1ZLQ_A_ACTA1507_0","NICKEL-BINDING PERIPLASMIC PROTEIN","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",3,"GLN A 190;HIS A 193;ARG A 194","None","1.10A","1zlqA-5vlhA:0.1","1zlqA-5vlhA:23.16"],["2DDW_A_PXLA1003_1","PYRIDOXINE KINASE","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",4,"VAL A 312;VAL A 336;LEU A 286;HIS A 391","None","1.00A","2ddwA-5vlhA:4.6","2ddwA-5vlhA:23.53"],["2UVN_B_ECNB1406_1","CYTOCHROME P450 130","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"ASP A 343;PRO A 345;THR A 353;GLY A 337;VAL A 441","None","1.46A","2uvnB-5vlhA:undetectable","2uvnB-5vlhA:24.85"],["2V7U_A_SAMA1299_0","5'-FLUORO-5'-DEOXY ADENOSINE SYNTHETASE","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",4,"PHE A 318;ASN A 354;SER A 386;ALA A 322","None","1.10A","2v7uA-5vlhA:5.3","2v7uA-5vlhA:23.11"],["3GCS_A_BAXA401_2","MITOGEN-ACTIVATED PROTEIN KINASE 14","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",4,"VAL A 336;LEU A 436;ILE A 395;ILE A 334","None","0.87A","3gcsA-5vlhA:undetectable","3gcsA-5vlhA:22.98"],["3KEE_A_30BA500_1","GENOME POLYPROTEIN","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"HIS A 226;ASP A 186;GLY A 384;SER A 386;ALA A 290","None","0.93A","3keeA-5vlhA:undetectable","3keeA-5vlhA:17.75"],["3KEE_B_30BB500_1","GENOME POLYPROTEIN","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"GLN A 382;HIS A 226;ASP A 186;GLY A 384;ALA A 290","None","0.95A","3keeB-5vlhA:undetectable","3keeB-5vlhA:17.75"],["3KEE_B_30BB500_1","GENOME POLYPROTEIN","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"GLN A 382;HIS A 226;ASP A 186;GLY A 384;SER A 386","None","0.87A","3keeB-5vlhA:undetectable","3keeB-5vlhA:17.75"],["3KEE_C_30BC500_2","GENOME POLYPROTEIN","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",4,"GLN A 433;PHE A 355;TYR A 325;LEU A 440","None","1.40A","3keeC-5vlhA:undetectable","3keeC-5vlhA:17.75"],["3KEE_D_30BD500_1","GENOME POLYPROTEIN","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",6,"GLN A 382;HIS A 226;ASP A 186;GLY A 384;SER A 386;ALA A 290","None","1.14A","3keeD-5vlhA:undetectable","3keeD-5vlhA:17.75"],["3KU1_G_SAMG226_0","SAM-DEPENDENT METHYLTRANSFERASE","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"VAL A 284;PRO A 282;ALA A 409;LEU A 415;ILE A 334","None","0.75A","3ku1G-5vlhA:undetectable","3ku1G-5vlhA:20.60"],["3KU1_H_SAMH226_0","SAM-DEPENDENT METHYLTRANSFERASE","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"VAL A 284;PRO A 282;ALA A 409;LEU A 415;ILE A 334","None","0.73A","3ku1H-5vlhA:undetectable","3ku1H-5vlhA:20.60"],["3LBD_A_9CRA424_1","RETINOIC ACID RECEPTOR GAMMA","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"ALA A 338;ILE A 424;PHE A 429;GLY A 356;ALA A 322","None","1.07A","3lbdA-5vlhA:undetectable","3lbdA-5vlhA:19.83"],["3OGP_B_017B200_2","FIV PROTEASE","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"GLY A 394;ALA A 393;ILE A 334;ILE A 368;LEU A 286","None","1.01A","3ogpB-5vlhA:undetectable","3ogpB-5vlhA:13.35"],["3SUD_A_SUEA1201_1","NS3 PROTEASE, NS4A PROTEIN","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"GLN A 382;HIS A 226;ASP A 186;GLY A 384;ALA A 290","None","1.01A","3sudA-5vlhA:undetectable","3sudA-5vlhA:19.70"],["3SUE_A_SUEA1201_1","NS3 PROTEASE, NS4A PROTEIN","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"GLN A 382;HIS A 226;ASP A 186;GLY A 384;SER A 386","None","0.93A","3sueA-5vlhA:undetectable","3sueA-5vlhA:19.95"],["3SUE_A_SUEA1201_1","NS3 PROTEASE, NS4A PROTEIN","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"HIS A 226;ASP A 186;GLY A 384;SER A 386;ALA A 290","None","0.96A","3sueA-5vlhA:undetectable","3sueA-5vlhA:19.95"],["3SUE_B_SUEB1201_1","NS3 PROTEASE, NS4A PROTEIN","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"GLN A 382;HIS A 226;ASP A 186;GLY A 384;ALA A 290","None","1.10A","3sueB-5vlhA:undetectable","3sueB-5vlhA:19.95"],["3SUE_B_SUEB1201_1","NS3 PROTEASE, NS4A PROTEIN","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"GLN A 382;HIS A 226;ASP A 186;GLY A 384;SER A 386","None","0.93A","3sueB-5vlhA:undetectable","3sueB-5vlhA:19.95"],["3SUE_C_SUEC1201_1","NS3 PROTEASE, NS4A PROTEIN","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"GLN A 382;HIS A 226;ASP A 186;GLY A 384;SER A 386","None","0.93A","3sueC-5vlhA:undetectable","3sueC-5vlhA:19.95"],["3SUE_C_SUEC1201_1","NS3 PROTEASE, NS4A PROTEIN","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"HIS A 226;ASP A 186;GLY A 384;SER A 386;ALA A 290","None","0.98A","3sueC-5vlhA:undetectable","3sueC-5vlhA:19.95"],["3SUE_D_SUED1201_1","NS3 PROTEASE, NS4A PROTEIN","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"GLN A 382;HIS A 226;ASP A 186;GLY A 384;SER A 386","None","0.89A","3sueD-5vlhA:undetectable","3sueD-5vlhA:19.95"],["3SUF_A_SUEA1201_1","NS3 PROTEASE, NS4A PROTEIN","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"GLN A 382;HIS A 226;ASP A 186;GLY A 384;ALA A 290","None","0.90A","3sufA-5vlhA:undetectable","3sufA-5vlhA:19.21"],["3SUF_A_SUEA1201_1","NS3 PROTEASE, NS4A PROTEIN","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"GLN A 382;HIS A 226;ASP A 186;GLY A 384;SER A 386","None","0.86A","3sufA-5vlhA:undetectable","3sufA-5vlhA:19.21"],["3SUF_B_SUEB1201_1","NS3 PROTEASE, NS4A PROTEIN","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"GLN A 382;HIS A 226;ASP A 186;GLY A 384;SER A 386","None","1.00A","3sufB-5vlhA:undetectable","3sufB-5vlhA:19.21"],["3SUF_B_SUEB1201_1","NS3 PROTEASE, NS4A PROTEIN","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"HIS A 226;ASP A 186;GLY A 384;SER A 386;ALA A 290","None","0.98A","3sufB-5vlhA:undetectable","3sufB-5vlhA:19.21"],["3SUF_C_SUEC1201_1","NS3 PROTEASE, NS4A PROTEIN","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"GLN A 382;HIS A 226;ASP A 186;GLY A 384;SER A 386","None","0.89A","3sufC-5vlhA:undetectable","3sufC-5vlhA:19.21"],["3SUF_C_SUEC1201_1","NS3 PROTEASE, NS4A PROTEIN","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"HIS A 226;ASP A 186;GLY A 384;SER A 386;ALA A 290","None","0.97A","3sufC-5vlhA:undetectable","3sufC-5vlhA:19.21"],["4L1A_A_AB1A101_2","MDR769 HIV-1 PROTEASE;MDR769 HIV-1 PROTEASE","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",4,"ASP A 360;GLY A 356;PRO A 345;THR A 339"," CA A 501 (-2.5A);None;None;None","1.11A","4l1aB-5vlhA:undetectable","4l1aB-5vlhA:15.41"],["4QVL_K_BO2K301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"ALA A 397;ALA A 393;GLY A 176;GLY A 244;ALA A 245","None","1.03A","4qvlK-5vlhA:undetectable;4qvlL-5vlhA:undetectable","4qvlK-5vlhA:18.52;4qvlL-5vlhA:21.10"],["4QVL_Y_BO2Y301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"ALA A 397;ALA A 393;GLY A 176;GLY A 244;ALA A 245","None","1.03A","4qvlY-5vlhA:undetectable;4qvlZ-5vlhA:undetectable","4qvlY-5vlhA:18.52;4qvlZ-5vlhA:21.10"],["4QVM_K_BO2K301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"ALA A 397;ALA A 393;GLY A 176;GLY A 244;ALA A 245","None","1.03A","4qvmK-5vlhA:undetectable;4qvmL-5vlhA:undetectable","4qvmK-5vlhA:18.46;4qvmL-5vlhA:21.10"],["4QVM_Y_BO2Y301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"ALA A 397;ALA A 393;GLY A 176;GLY A 244;ALA A 245","None","1.03A","4qvmY-5vlhA:undetectable;4qvmZ-5vlhA:undetectable","4qvmY-5vlhA:18.46;4qvmZ-5vlhA:21.10"],["4QVP_K_BO2K301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"ALA A 397;ALA A 393;GLY A 176;GLY A 244;ALA A 245","None","1.02A","4qvpK-5vlhA:undetectable;4qvpL-5vlhA:undetectable","4qvpK-5vlhA:18.90;4qvpL-5vlhA:21.10"],["4QVP_Y_BO2Y301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"ALA A 397;ALA A 393;GLY A 176;GLY A 244;ALA A 245","None","1.02A","4qvpY-5vlhA:undetectable;4qvpZ-5vlhA:undetectable","4qvpY-5vlhA:18.90;4qvpZ-5vlhA:21.10"],["4QW1_K_BO2K301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"ALA A 397;ALA A 393;GLY A 176;GLY A 244;ALA A 245","None","1.00A","4qw1K-5vlhA:undetectable;4qw1L-5vlhA:undetectable","4qw1K-5vlhA:18.74;4qw1L-5vlhA:21.10"],["4QW1_Y_BO2Y301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"ALA A 397;ALA A 393;GLY A 176;GLY A 244;ALA A 245","None","1.00A","4qw1Y-5vlhA:undetectable;4qw1Z-5vlhA:undetectable","4qw1Y-5vlhA:18.74;4qw1Z-5vlhA:21.10"],["4QW3_K_BO2K301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"ALA A 397;ALA A 393;GLY A 176;GLY A 244;ALA A 245","None","1.02A","4qw3K-5vlhA:undetectable;4qw3L-5vlhA:undetectable","4qw3K-5vlhA:18.46;4qw3L-5vlhA:21.10"],["4QW3_Y_BO2Y301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"ALA A 397;ALA A 393;GLY A 176;GLY A 244;ALA A 245","None","1.02A","4qw3Y-5vlhA:undetectable;4qw3Z-5vlhA:undetectable","4qw3Y-5vlhA:18.46;4qw3Z-5vlhA:21.10"],["5BXN_K_BO2K301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"ALA A 397;ALA A 393;GLY A 176;GLY A 244;ALA A 245","None","1.02A","5bxnK-5vlhA:undetectable;5bxnL-5vlhA:undetectable","5bxnK-5vlhA:18.52;5bxnL-5vlhA:21.10"],["5BXN_Y_BO2Y301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"ALA A 397;ALA A 393;GLY A 176;GLY A 244;ALA A 245","None","1.03A","5bxnY-5vlhA:undetectable;5bxnZ-5vlhA:undetectable","5bxnY-5vlhA:18.52;5bxnZ-5vlhA:21.10"],["5D0X_K_BO2K301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",6,"SER A 401;ALA A 397;ALA A 393;GLY A 176;GLY A 244;ALA A 245","None","1.27A","5d0xK-5vlhA:undetectable;5d0xL-5vlhA:undetectable","5d0xK-5vlhA:18.52;5d0xL-5vlhA:21.10"],["5D0X_Y_BO2Y301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",6,"SER A 401;ALA A 397;ALA A 393;GLY A 176;GLY A 244;ALA A 245","None","1.24A","5d0xY-5vlhA:undetectable;5d0xZ-5vlhA:undetectable","5d0xY-5vlhA:18.52;5d0xZ-5vlhA:21.10"],["5EEV_L_TRPL101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",4,"THR A 437;GLY A 337;ALA A 322;THR A 353","None","0.97A","5eevL-5vlhA:undetectable;5eevV-5vlhA:undetectable","5eevL-5vlhA:9.83;5eevV-5vlhA:9.83"],["5EEW_L_TRPL101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",4,"THR A 437;GLY A 337;ALA A 322;THR A 353","None","0.97A","5eewL-5vlhA:undetectable;5eewV-5vlhA:undetectable","5eewL-5vlhA:9.83;5eewV-5vlhA:9.83"],["5EF3_L_TRPL101_0","TRANSCRIPTION ATTENUATION PROTEIN MTRB","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",4,"THR A 437;GLY A 337;ALA A 322;THR A 353","None","0.96A","5ef3L-5vlhA:undetectable;5ef3V-5vlhA:undetectable","5ef3L-5vlhA:9.83;5ef3V-5vlhA:9.83"],["6C2M_C_SUEC1203_0","NS3 PROTEASE","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",6,"GLN A 382;HIS A 226;ASP A 186;GLY A 384;SER A 386;ALA A 290","None","1.14A","6c2mC-5vlhA:undetectable","6c2mC-5vlhA:11.01"],["6CE2_B_SVRB202_2","-","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"LEU A 304;LEU A 118;GLY A 267;GLY A 263;ASN A 298","None","1.13A","6ce2B-5vlhA:undetectable","6ce2B-5vlhA:14.40"],["6CLX_A_SAMA401_0","O-METHYLTRANSFERASE","5vlh","PROPROTEIN CONVERTASE SUBTILISIN\/KEXIN TYPE 9","Homo sapiens",5,"ASP A 129;ALA A 134;GLY A  76;GLY A 128;VAL A 124","None","1.28A","6clxA-5vlhA:undetectable","6clxA-5vlhA:23.49"]]