SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vlp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
4 / 4 THR H 128
PRO H 158
THR H 127
PRO H 129
None
1.32A 1dsdC-5vlpH:
undetectable
1dsdC-5vlpH:
6.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
4 / 4 THR H 128
PRO H 158
THR H 127
PRO H 129
None
1.32A 1dsdC-5vlpH:
undetectable
1dsdC-5vlpH:
6.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 7 GLY H  54
PRO H  53
THR H  58
ILE H  51
GLY H  56
None
1.21A 1usqA-5vlpH:
undetectable
1usqA-5vlpH:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEO_A_017A402_2
(PROTEASE)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 12 LEU H 149
VAL H 174
GLY H 168
VAL H 194
VAL H 192
None
0.90A 2ieoB-5vlpH:
undetectable
2ieoB-5vlpH:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 7 GLY H  54
PRO H  53
THR H  58
ILE H  51
GLY H  56
None
1.22A 2jklA-5vlpH:
undetectable
2jklA-5vlpH:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 7 GLY H  54
PRO H  53
THR H  58
ILE H  51
GLY H  56
None
1.23A 2jklC-5vlpH:
undetectable
2jklC-5vlpH:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 7 GLY H  54
PRO H  53
THR H  58
ILE H  51
GLY H  56
None
1.22A 2jklD-5vlpH:
undetectable
2jklD-5vlpH:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 7 GLY H  54
PRO H  53
THR H  58
ILE H  51
GLY H  56
None
1.22A 2jklF-5vlpH:
undetectable
2jklF-5vlpH:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNP_A_ROCA401_2
(PROTEASE)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 11 LEU H 149
VAL H 174
GLY H 168
VAL H 194
VAL H 192
None
1.02A 2nnpB-5vlpH:
undetectable
2nnpB-5vlpH:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D9L_A_ACTA501_0
(CTD-PEPTIDE
RNA-BINDING PROTEIN
16)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
4 / 5 ILE H  34
PRO H  53
TYR H  52
TYR H  33
None
1.01A 3d9lA-5vlpH:
undetectable
3d9lY-5vlpH:
undetectable
3d9lA-5vlpH:
17.49
3d9lY-5vlpH:
5.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QN9_B_DXCB610_0
(N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
3 / 3 GLY H  42
PRO H  41
ALA H  92
None
0.48A 4qn9B-5vlpH:
undetectable
4qn9B-5vlpH:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 11 HIS H 210
SER H 160
THR H 127
ALA H   9
THR H 118
None
1.46A 4qvlV-5vlpH:
undetectable
4qvlb-5vlpH:
undetectable
4qvlV-5vlpH:
22.27
4qvlb-5vlpH:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 11 HIS H 210
SER H 160
THR H 127
ALA H   9
THR H 118
None
1.45A 4qvlH-5vlpH:
undetectable
4qvlN-5vlpH:
undetectable
4qvlH-5vlpH:
22.27
4qvlN-5vlpH:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 11 HIS H 210
SER H 160
THR H 127
ALA H   9
THR H 118
None
1.47A 4qvmV-5vlpH:
undetectable
4qvmb-5vlpH:
undetectable
4qvmV-5vlpH:
22.27
4qvmb-5vlpH:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 11 HIS H 210
SER H 160
THR H 127
ALA H   9
THR H 118
None
1.46A 4qvmH-5vlpH:
undetectable
4qvmN-5vlpH:
undetectable
4qvmH-5vlpH:
22.27
4qvmN-5vlpH:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 11 HIS H 210
SER H 160
THR H 127
ALA H   9
THR H 118
None
1.44A 4qvpV-5vlpH:
undetectable
4qvpb-5vlpH:
undetectable
4qvpV-5vlpH:
22.27
4qvpb-5vlpH:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 11 HIS H 210
SER H 160
THR H 127
ALA H   9
THR H 118
None
1.43A 4qvpH-5vlpH:
undetectable
4qvpN-5vlpH:
undetectable
4qvpH-5vlpH:
22.27
4qvpN-5vlpH:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 11 HIS H 210
SER H 160
THR H 127
ALA H   9
THR H 118
None
1.43A 4qvqV-5vlpH:
undetectable
4qvqb-5vlpH:
undetectable
4qvqV-5vlpH:
22.27
4qvqb-5vlpH:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 11 HIS H 210
SER H 160
THR H 127
ALA H   9
THR H 118
None
1.43A 4qvqH-5vlpH:
undetectable
4qvqN-5vlpH:
undetectable
4qvqH-5vlpH:
22.27
4qvqN-5vlpH:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 10 HIS H 210
SER H 160
THR H 127
ALA H   9
THR H 118
None
1.46A 4qvvV-5vlpH:
undetectable
4qvvb-5vlpH:
undetectable
4qvvV-5vlpH:
22.27
4qvvb-5vlpH:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 10 HIS H 210
SER H 160
THR H 127
ALA H   9
THR H 118
None
1.43A 4qvvH-5vlpH:
undetectable
4qvvN-5vlpH:
undetectable
4qvvH-5vlpH:
22.27
4qvvN-5vlpH:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 11 HIS H 210
SER H 160
THR H 127
ALA H   9
THR H 118
None
1.46A 4qvwV-5vlpH:
undetectable
4qvwb-5vlpH:
undetectable
4qvwV-5vlpH:
22.27
4qvwb-5vlpH:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 11 HIS H 210
SER H 160
THR H 127
ALA H   9
THR H 118
None
1.46A 4qvwH-5vlpH:
undetectable
4qvwN-5vlpH:
undetectable
4qvwH-5vlpH:
22.27
4qvwN-5vlpH:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 11 HIS H 210
SER H 160
THR H 127
ALA H   9
THR H 118
None
1.44A 4qvyV-5vlpH:
undetectable
4qvyb-5vlpH:
undetectable
4qvyV-5vlpH:
22.27
4qvyb-5vlpH:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 11 HIS H 210
SER H 160
THR H 127
ALA H   9
THR H 118
None
1.43A 4qvyH-5vlpH:
undetectable
4qvyN-5vlpH:
undetectable
4qvyH-5vlpH:
22.27
4qvyN-5vlpH:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 11 HIS H 210
SER H 160
THR H 127
ALA H   9
THR H 118
None
1.47A 4qw0V-5vlpH:
undetectable
4qw0b-5vlpH:
undetectable
4qw0V-5vlpH:
22.27
4qw0b-5vlpH:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 11 HIS H 210
SER H 160
THR H 127
ALA H   9
THR H 118
None
1.45A 4qw0H-5vlpH:
undetectable
4qw0N-5vlpH:
undetectable
4qw0H-5vlpH:
22.27
4qw0N-5vlpH:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 11 HIS H 210
SER H 160
THR H 127
ALA H   9
THR H 118
None
1.45A 4qw1V-5vlpH:
undetectable
4qw1b-5vlpH:
undetectable
4qw1V-5vlpH:
22.27
4qw1b-5vlpH:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 11 HIS H 210
SER H 160
THR H 127
ALA H   9
THR H 118
None
1.46A 4qw1H-5vlpH:
undetectable
4qw1N-5vlpH:
undetectable
4qw1H-5vlpH:
22.27
4qw1N-5vlpH:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 11 HIS H 210
SER H 160
THR H 127
ALA H   9
THR H 118
None
1.45A 4qw3V-5vlpH:
undetectable
4qw3b-5vlpH:
undetectable
4qw3V-5vlpH:
22.27
4qw3b-5vlpH:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 11 HIS H 210
SER H 160
THR H 127
ALA H   9
THR H 118
None
1.45A 4qw3H-5vlpH:
undetectable
4qw3N-5vlpH:
undetectable
4qw3H-5vlpH:
22.27
4qw3N-5vlpH:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 11 HIS H 210
SER H 160
THR H 127
ALA H   9
THR H 118
None
1.46A 4qwuV-5vlpH:
undetectable
4qwub-5vlpH:
undetectable
4qwuV-5vlpH:
22.27
4qwub-5vlpH:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 11 HIS H 210
SER H 160
THR H 127
ALA H   9
THR H 118
None
1.46A 4qwuH-5vlpH:
undetectable
4qwuN-5vlpH:
undetectable
4qwuH-5vlpH:
22.27
4qwuN-5vlpH:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 11 HIS H 210
SER H 160
THR H 127
ALA H   9
THR H 118
None
1.42A 5bxnV-5vlpH:
undetectable
5bxnb-5vlpH:
undetectable
5bxnV-5vlpH:
22.27
5bxnb-5vlpH:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 11 HIS H 210
SER H 160
THR H 127
ALA H   9
THR H 118
None
1.43A 5bxnH-5vlpH:
undetectable
5bxnN-5vlpH:
undetectable
5bxnH-5vlpH:
22.27
5bxnN-5vlpH:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 11 HIS H 210
SER H 160
THR H 127
ALA H   9
THR H 118
None
1.46A 5cz7H-5vlpH:
undetectable
5cz7N-5vlpH:
undetectable
5cz7H-5vlpH:
22.27
5cz7N-5vlpH:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 11 HIS H 210
SER H 160
THR H 127
ALA H   9
THR H 118
None
1.45A 5d0xV-5vlpH:
undetectable
5d0xb-5vlpH:
undetectable
5d0xV-5vlpH:
22.27
5d0xb-5vlpH:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 11 HIS H 210
SER H 160
THR H 127
ALA H   9
THR H 118
None
1.46A 5d0xH-5vlpH:
undetectable
5d0xN-5vlpH:
undetectable
5d0xH-5vlpH:
22.27
5d0xN-5vlpH:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 11 HIS H 210
SER H 160
THR H 127
ALA H   9
THR H 118
None
1.44A 5l5fV-5vlpH:
undetectable
5l5fb-5vlpH:
undetectable
5l5fV-5vlpH:
22.27
5l5fb-5vlpH:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 11 HIS H 210
SER H 160
THR H 127
ALA H   9
THR H 118
None
1.44A 5l5fH-5vlpH:
undetectable
5l5fN-5vlpH:
undetectable
5l5fH-5vlpH:
22.27
5l5fN-5vlpH:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 11 HIS H 210
SER H 160
THR H 127
ALA H   9
THR H 118
None
1.44A 5l66V-5vlpH:
undetectable
5l66b-5vlpH:
undetectable
5l66V-5vlpH:
22.27
5l66b-5vlpH:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
5 / 11 HIS H 210
SER H 160
THR H 127
ALA H   9
THR H 118
None
1.43A 5l66H-5vlpH:
undetectable
5l66N-5vlpH:
undetectable
5l66H-5vlpH:
22.27
5l66N-5vlpH:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
4 / 6 ASN H  78
ALA H  24
PRO H  53
VAL H  79
None
1.11A 5umd2-5vlpH:
undetectable
5umdF-5vlpH:
undetectable
5umd2-5vlpH:
19.52
5umdF-5vlpH:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5vlp FAB7G7 HEAVY CHAIN
(Mus
musculus)
4 / 6 LEU H  37
MET H  81
THR H  69
LEU H  70
None
1.09A 5x1fA-5vlpH:
undetectable
5x1fJ-5vlpH:
undetectable
5x1fA-5vlpH:
18.70
5x1fJ-5vlpH:
15.62