SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vm0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7I_A_017A200_2
(POL POLYPROTEIN)		 5vm0 CAMELID NANOBODY VHH
T9
(Lama
glama) 		4 / 7 ASP A  64
VAL A  66
GLY A  52
ILE A  53
 None
 0.78A 1t7iB-5vm0A:
undetectable		 1t7iB-5vm0A:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7J_A_478A200_2
(POL POLYPROTEIN)		 5vm0 CAMELID NANOBODY VHH
T9
(Lama
glama) 		4 / 7 ASP A  64
VAL A  66
GLY A  52
ILE A  53
 None
 0.82A 1t7jB-5vm0A:
undetectable		 1t7jB-5vm0A:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_1
(PROTEASE)		 5vm0 CAMELID NANOBODY VHH
T9
(Lama
glama) 		4 / 8 ASP A  64
VAL A  66
GLY A  52
ILE A  53
 None
 0.79A 3nu9A-5vm0A:
undetectable		 3nu9A-5vm0A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUG_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5vm0 CAMELID NANOBODY VHH
T9
(Lama
glama) 		5 / 12 GLY A  58
GLY A  52
ALA A  60
THR A  71
ALA A  70
 None
None
EDO  A 201 ( 3.8A)
EDO  A 201 ( 4.3A)
None
 0.95A 3sugA-5vm0A:
undetectable		 3sugA-5vm0A:
17.35