SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vmk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7R_A_NCTA440_1
(CYTOCHROME P450-CAM)		 5vmk BIFUNCTIONAL PROTEIN
GLMU
(Acinetobacter
baumannii) 		4 / 7 PHE A 251
VAL A 263
VAL A 269
ILE A 271
 None
 1.00A 1p7rA-5vmkA:
undetectable		 1p7rA-5vmkA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_B_RBFB596_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 5vmk BIFUNCTIONAL PROTEIN
GLMU
(Acinetobacter
baumannii) 		5 / 11 THR A 110
VAL A 103
GLU A 219
GLU A 221
ILE A 169
 None
 1.36A 1t6zB-5vmkA:
2.6		 1t6zB-5vmkA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_B_SAMB302_0
(RRNA
METHYLTRANSFERASE)		 5vmk BIFUNCTIONAL PROTEIN
GLMU
(Acinetobacter
baumannii) 		5 / 10 GLU A  72
GLY A  55
ILE A  51
MET A  85
ALA A  10
 None
 1.13A 1x7pA-5vmkA:
2.9
1x7pB-5vmkA:
undetectable		 1x7pA-5vmkA:
22.00
1x7pB-5vmkA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5vmk BIFUNCTIONAL PROTEIN
GLMU
(Acinetobacter
baumannii) 		5 / 12 ASN A  47
LEU A   8
ALA A   9
VAL A 172
LEU A  90
 None
 1.10A 1xdkA-5vmkA:
undetectable		 1xdkA-5vmkA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A8T_B_ADNB252_1
(U8 SNORNA-BINDING
PROTEIN X29)		 5vmk BIFUNCTIONAL PROTEIN
GLMU
(Acinetobacter
baumannii) 		4 / 8 GLY A 370
ILE A 369
ASN A 374
SER A 373
 None
 0.93A 2a8tB-5vmkA:
undetectable		 2a8tB-5vmkA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA501_1
(CYTOCHROME P450 2B4)		 5vmk BIFUNCTIONAL PROTEIN
GLMU
(Acinetobacter
baumannii) 		4 / 7 SER A  18
MET A  16
GLY A  11
ILE A   7
 None
None
PO4  A 502 (-3.3A)
None
 1.02A 2bdmA-5vmkA:
undetectable		 2bdmA-5vmkA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CD2_A_FOLA307_0
(DIHYDROFOLATE
REDUCTASE)		 5vmk BIFUNCTIONAL PROTEIN
GLMU
(Acinetobacter
baumannii) 		5 / 12 ALA A 367
LEU A 406
ILE A 375
PHE A 399
THR A 350
 None
 0.92A 2cd2A-5vmkA:
undetectable		 2cd2A-5vmkA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_1
(CYTOCHROME P450 2R1)		 5vmk BIFUNCTIONAL PROTEIN
GLMU
(Acinetobacter
baumannii) 		5 / 12 LEU A 295
GLY A 314
VAL A 287
ILE A 289
THR A 304
 None
 0.95A 3c6gA-5vmkA:
undetectable		 3c6gA-5vmkA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 5vmk BIFUNCTIONAL PROTEIN
GLMU
(Acinetobacter
baumannii) 		5 / 12 ILE A 123
GLY A 124
VAL A 172
ILE A 169
ALA A 210
 None
 1.00A 3fpjA-5vmkA:
undetectable		 3fpjA-5vmkA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_2
(HIV-1 PROTEASE)		 5vmk BIFUNCTIONAL PROTEIN
GLMU
(Acinetobacter
baumannii) 		5 / 10 ALA A 358
VAL A 347
ILE A 352
ALA A 327
VAL A 345
 None
 1.04A 3t3cB-5vmkA:
undetectable		 3t3cB-5vmkA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_A_CAMA423_0
(CYTOCHROME P450)		 5vmk BIFUNCTIONAL PROTEIN
GLMU
(Acinetobacter
baumannii) 		5 / 9 TRP A  70
THR A  62
THR A  50
LEU A  33
GLY A  34
 None
 1.37A 4c9pA-5vmkA:
undetectable		 4c9pA-5vmkA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_B_CAMB423_0
(CYTOCHROME P450)		 5vmk BIFUNCTIONAL PROTEIN
GLMU
(Acinetobacter
baumannii) 		5 / 10 TRP A  70
THR A  62
THR A  50
LEU A  33
GLY A  34
 None
 1.31A 4c9pB-5vmkA:
undetectable		 4c9pB-5vmkA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5vmk BIFUNCTIONAL PROTEIN
GLMU
(Acinetobacter
baumannii) 		4 / 7 GLU A 338
THR A 321
THR A 351
SER A 356
 None
 0.87A 4pfjA-5vmkA:
undetectable		 4pfjA-5vmkA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 5vmk BIFUNCTIONAL PROTEIN
GLMU
(Acinetobacter
baumannii) 		4 / 7 LEU A  99
THR A 167
THR A 110
LEU A 114
 None
 0.88A 4z91F-5vmkA:
undetectable
4z91G-5vmkA:
undetectable
4z91H-5vmkA:
undetectable
4z91I-5vmkA:
undetectable
4z91J-5vmkA:
undetectable		 4z91F-5vmkA:
21.60
4z91G-5vmkA:
21.60
4z91H-5vmkA:
21.60
4z91I-5vmkA:
21.60
4z91J-5vmkA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_F_ACTF1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 5vmk BIFUNCTIONAL PROTEIN
GLMU
(Acinetobacter
baumannii) 		3 / 3 TYR A 194
THR A  79
THR A 196
 None
 0.60A 5aoxE-5vmkA:
undetectable		 5aoxE-5vmkA:
10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_F_ACTF1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 5vmk BIFUNCTIONAL PROTEIN
GLMU
(Acinetobacter
baumannii) 		3 / 3 TYR A 363
THR A 362
THR A 381
 CIT  A 501 (-4.7A)
None
None
 0.82A 5aoxE-5vmkA:
undetectable		 5aoxE-5vmkA:
10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_A_FUAA1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 5vmk BIFUNCTIONAL PROTEIN
GLMU
(Acinetobacter
baumannii) 		4 / 5 ILE A 369
ILE A 341
HIS A 340
VAL A 339
 None
 1.03A 5jmnA-5vmkA:
undetectable		 5jmnA-5vmkA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA504_1
(-)		 5vmk BIFUNCTIONAL PROTEIN
GLMU
(Acinetobacter
baumannii) 		4 / 8 VAL A 398
ILE A 375
ALA A 367
THR A 392
 None
 0.77A 5og9A-5vmkA:
undetectable		 5og9A-5vmkA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_D_EY4D500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5vmk BIFUNCTIONAL PROTEIN
GLMU
(Acinetobacter
baumannii) 		4 / 7 ILE A  49
VAL A   5
PRO A  91
ALA A  40
 None
 0.85A 6cduC-5vmkA:
undetectable
6cduD-5vmkA:
undetectable		 6cduC-5vmkA:
21.33
6cduD-5vmkA:
21.33