SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vmn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DEU_B_SALB306_1 (TRANSCRIPTIONAL REGULATOR SLYA)	5vmn	BAK PROTEIN (Singapore grouper iridovirus)	4 / 6	THR A 30 ILE A 72 SER A 73 LEU A 75	None	0.93A	3deuB-5vmnA: undetectable	3deuB-5vmnA: 20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G4L_C_ROFC903_1 (CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D)	5vmn	BAK PROTEIN (Singapore grouper iridovirus)	3 / 3	SER A 73 GLN A 74 PHE A 77	None	0.69A	3g4lC-5vmnA: undetectable	3g4lC-5vmnA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G4L_D_ROFD904_1 (CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D)	5vmn	BAK PROTEIN (Singapore grouper iridovirus)	3 / 3	ASN A 3 MET A 26 PHE A 6	NO3 A 206 (-4.8A) None NO3 A 206 ( 4.6A)	0.81A	3g4lD-5vmnA: undetectable	3g4lD-5vmnA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4BBO_D_ACTD1113_0 (BLR5658 PROTEIN)	5vmn	BAK PROTEIN (Singapore grouper iridovirus)	4 / 4	TRP A 112 LEU A 70 LEU A 9 THR A 19	NO3 A 206 ( 4.1A) None None None	1.46A	4bboD-5vmnA: undetectable	4bboD-5vmnA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6C06_D_FI8D1404_0 (DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA')	5vmn	BAK PROTEIN (Singapore grouper iridovirus)	4 / 8	ILE A 89 THR A 90 GLN A 92 ARG A 95	None NO3 A 205 ( 4.9A) None None	1.06A	6c06C-5vmnA: undetectable	6c06C-5vmnA: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3DEU_B_SALB306_1","TRANSCRIPTIONAL REGULATOR SLYA","5vmn","BAK PROTEIN","Singapore grouper iridovirus",4,"THR A  30;ILE A  72;SER A  73;LEU A  75","None","0.93A","3deuB-5vmnA:undetectable","3deuB-5vmnA:20.71"],["3G4L_C_ROFC903_1","CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D","5vmn","BAK PROTEIN","Singapore grouper iridovirus",3,"SER A  73;GLN A  74;PHE A  77","None","0.69A","3g4lC-5vmnA:undetectable","3g4lC-5vmnA:undetectable"],["3G4L_D_ROFD904_1","CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D","5vmn","BAK PROTEIN","Singapore grouper iridovirus",3,"ASN A   3;MET A  26;PHE A   6","NO3 A 206 (-4.8A);None;NO3 A 206 ( 4.6A)","0.81A","3g4lD-5vmnA:undetectable","3g4lD-5vmnA:undetectable"],["4BBO_D_ACTD1113_0","BLR5658 PROTEIN","5vmn","BAK PROTEIN","Singapore grouper iridovirus",4,"TRP A 112;LEU A  70;LEU A   9;THR A  19","NO3 A 206 ( 4.1A);None;None;None","1.46A","4bboD-5vmnA:undetectable","4bboD-5vmnA:undetectable"],["6C06_D_FI8D1404_0","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA;DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","5vmn","BAK PROTEIN","Singapore grouper iridovirus",4,"ILE A  89;THR A  90;GLN A  92;ARG A  95","None;NO3 A 205 ( 4.9A);None;None","1.06A","6c06C-5vmnA:undetectable","6c06C-5vmnA:undetectable"]]