SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vmt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_G_CCSG149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		4 / 7 ASN A 315
TYR A 319
ASN A 154
TYR A 313
 NAD  A 401 (-3.7A)
NAD  A 401 (-3.5A)
None
None
 1.02A 1dssG-5vmtA:
47.5		 1dssG-5vmtA:
48.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_G_CCSG149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		7 / 7 SER A 150
THR A 152
ASN A 154
CYH A 155
TYR A 313
ASN A 315
TYR A 319
 None
None
None
None
None
NAD  A 401 (-3.7A)
NAD  A 401 (-3.5A)
 0.26A 1dssG-5vmtA:
47.5		 1dssG-5vmtA:
48.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_R_CCSR149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		4 / 8 ASN A 315
TYR A 319
ASN A 154
TYR A 313
 NAD  A 401 (-3.7A)
NAD  A 401 (-3.5A)
None
None
 1.01A 1dssR-5vmtA:
47.4		 1dssR-5vmtA:
48.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_R_CCSR149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		8 / 8 SER A 150
THR A 152
ASN A 154
CYH A 155
HIS A 178
TYR A 313
ASN A 315
TYR A 319
 None
None
None
None
None
None
NAD  A 401 (-3.7A)
NAD  A 401 (-3.5A)
 0.45A 1dssR-5vmtA:
47.4		 1dssR-5vmtA:
48.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_1
(HIV-1 PROTEASE)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		5 / 10 LEU A  94
VAL A  32
ILE A  65
VAL A   5
ILE A   7
 None
 0.89A 1hsgA-5vmtA:
undetectable		 1hsgA-5vmtA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_3
(HIV-1 PROTEASE)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		5 / 12 LEU A  94
VAL A  32
ILE A  65
VAL A   5
ILE A   7
 None
 0.83A 1hxbB-5vmtA:
undetectable		 1hxbB-5vmtA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JZS_A_MRCA1301_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		5 / 11 PRO A 236
GLY A 182
ASP A 183
GLN A 184
ILE A  13
 None
None
None
None
NAD  A 401 (-4.2A)
 1.17A 1jzsA-5vmtA:
undetectable		 1jzsA-5vmtA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OHR_A_1UNA201_2
(ASPARTYLPROTEASE)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		5 / 9 LEU A  94
VAL A  32
ILE A  65
VAL A   5
ILE A   7
 None
 0.94A 1ohrB-5vmtA:
undetectable		 1ohrB-5vmtA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_A_9CRA801_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		6 / 12 ILE A 258
ALA A 261
ALA A 260
PHE A 291
ALA A 265
VAL A 298
 None
 1.28A 1xlsA-5vmtA:
undetectable		 1xlsA-5vmtA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_A_9CRA801_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		6 / 12 ILE A 258
ALA A 261
ALA A 260
PHE A 291
ALA A 265
VAL A 307
 None
 1.44A 1xlsA-5vmtA:
undetectable		 1xlsA-5vmtA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_B_9CRB802_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		6 / 12 ILE A 258
ALA A 261
ALA A 260
PHE A 291
ALA A 265
VAL A 298
 None
 1.27A 1xlsB-5vmtA:
undetectable		 1xlsB-5vmtA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_B_9CRB802_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		6 / 12 ILE A 258
ALA A 261
ALA A 260
PHE A 291
ALA A 265
VAL A 307
 None
 1.45A 1xlsB-5vmtA:
undetectable		 1xlsB-5vmtA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_C_9CRC803_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		6 / 12 ILE A 258
ALA A 261
ALA A 260
PHE A 291
ALA A 265
VAL A 298
 None
 1.27A 1xlsC-5vmtA:
undetectable		 1xlsC-5vmtA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_C_9CRC803_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		6 / 12 ILE A 258
ALA A 261
ALA A 260
PHE A 291
ALA A 265
VAL A 307
 None
 1.45A 1xlsC-5vmtA:
undetectable		 1xlsC-5vmtA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_D_9CRD804_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		6 / 12 ILE A 258
ALA A 261
ALA A 260
PHE A 291
ALA A 265
VAL A 298
 None
 1.27A 1xlsD-5vmtA:
undetectable		 1xlsD-5vmtA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_D_9CRD804_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		6 / 12 ILE A 258
ALA A 261
ALA A 260
PHE A 291
ALA A 265
VAL A 307
 None
 1.44A 1xlsD-5vmtA:
undetectable		 1xlsD-5vmtA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_B_VIAB902_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		5 / 12 TYR A 319
ALA A 121
ILE A 119
ALA A  17
ILE A   7
 NAD  A 401 (-3.5A)
NAD  A 401 (-3.2A)
None
None
None
 1.00A 2h42B-5vmtA:
undetectable		 2h42B-5vmtA:
19.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DMT_C_CCSC166_0
(GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
GLYCOSOMAL)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		8 / 8 SER A 150
THR A 152
ASN A 154
CYH A 155
HIS A 178
TYR A 313
ASN A 315
TYR A 319
 None
None
None
None
None
None
NAD  A 401 (-3.7A)
NAD  A 401 (-3.5A)
 0.38A 3dmtC-5vmtA:
47.2		 3dmtC-5vmtA:
44.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_2
(PROTEASE)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		5 / 10 LEU A  94
VAL A  32
ILE A  65
VAL A   5
ILE A   7
 None
 0.96A 3em3B-5vmtA:
undetectable		 3em3B-5vmtA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEC_A_STIA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		4 / 4 LEU A 327
MET A 317
ILE A  72
ASP A  34
 None
None
None
NAD  A 401 (-3.0A)
 1.32A 3hecA-5vmtA:
undetectable		 3hecA-5vmtA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		5 / 12 TYR A 313
ASN A 225
GLY A 212
ALA A 213
GLY A 218
 None
 0.91A 3hs6B-5vmtA:
undetectable		 3hs6B-5vmtA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_2
(GAG-POL POLYPROTEIN)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		5 / 12 LEU A  94
VAL A  32
ILE A  65
VAL A   5
ILE A   7
 None
 0.92A 3jvyB-5vmtA:
undetectable		 3jvyB-5vmtA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW5_A_TOPA208_1
(DIHYDROFOLATE
REDUCTASE)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		5 / 11 ALA A  24
GLU A 328
LEU A 327
VAL A 324
ILE A   7
 None
 0.99A 3jw5A-5vmtA:
undetectable		 3jw5A-5vmtA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW5_B_TOPB208_1
(DIHYDROFOLATE
REDUCTASE)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		5 / 10 ALA A  24
GLU A 328
LEU A 327
VAL A 324
ILE A   7
 None
 0.97A 3jw5B-5vmtA:
undetectable		 3jw5B-5vmtA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_1
(HIV-1 PROTEASE)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		5 / 12 LEU A  94
VAL A  32
ILE A  65
VAL A   5
ILE A   7
 None
 0.80A 3k4vC-5vmtA:
undetectable		 3k4vC-5vmtA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_2
(HIV-1 PROTEASE)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		5 / 12 LEU A  94
VAL A  32
ILE A  65
VAL A   5
ILE A   7
 None
 0.86A 3mwsB-5vmtA:
undetectable		 3mwsB-5vmtA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_2
(PROTEASE)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		3 / 3 ARG A  15
VAL A 283
THR A 239
 None
 0.63A 3ndtA-5vmtA:
undetectable		 3ndtA-5vmtA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_1
(PROTEASE)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		5 / 12 LEU A  94
VAL A  32
ILE A  65
VAL A   5
ILE A   7
 None
 0.80A 3nduC-5vmtA:
undetectable		 3nduC-5vmtA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		5 / 12 TYR A 313
ASN A 225
GLY A 212
ALA A 213
GLY A 218
 None
 0.83A 4e1gA-5vmtA:
undetectable		 4e1gA-5vmtA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		5 / 10 SER A 147
THR A 152
THR A 153
ALA A 121
THR A 101
 None
None
None
NAD  A 401 (-3.2A)
None
 1.50A 4qvvH-5vmtA:
undetectable
4qvvN-5vmtA:
undetectable		 4qvvH-5vmtA:
21.47
4qvvN-5vmtA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		5 / 11 SER A 147
THR A 152
THR A 153
ALA A 121
THR A 101
 None
None
None
NAD  A 401 (-3.2A)
None
 1.49A 4qvyV-5vmtA:
undetectable
4qvyb-5vmtA:
undetectable		 4qvyV-5vmtA:
21.47
4qvyb-5vmtA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		5 / 11 SER A 147
THR A 152
THR A 153
ALA A 121
THR A 101
 None
None
None
NAD  A 401 (-3.2A)
None
 1.50A 4qvyH-5vmtA:
undetectable
4qvyN-5vmtA:
undetectable		 4qvyH-5vmtA:
21.47
4qvyN-5vmtA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_B_SAMB1548_0
(CYSTATHIONINE
BETA-SYNTHASE)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		5 / 11 SER A 150
LEU A 156
PRO A 158
VAL A 131
THR A 129
 None
 1.27A 4uuuB-5vmtA:
undetectable		 4uuuB-5vmtA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		4 / 4 ASN A 154
SER A 120
ALA A 148
VAL A 130
 None
NAD  A 401 (-3.2A)
None
None
 1.39A 4x1kC-5vmtA:
3.0		 4x1kC-5vmtA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERS_A_ACTA803_0
(GEPHYRIN)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		3 / 3 THR A 153
ALA A 149
ASN A 154
 None
 0.59A 5ersA-5vmtA:
undetectable		 5ersA-5vmtA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		4 / 6 PRO A  80
GLU A 143
ALA A 148
LEU A 323
 None
 0.93A 5igiA-5vmtA:
undetectable		 5igiA-5vmtA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_CE9A402_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		5 / 12 ALA A 232
HIS A 178
TYR A 313
LEU A 242
THR A 243
 None
 1.15A 5k9dA-5vmtA:
undetectable		 5k9dA-5vmtA:
25.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		4 / 4 ASN A 154
SER A 120
ALA A 148
VAL A 130
 None
NAD  A 401 (-3.2A)
None
None
 1.35A 5nm5A-5vmtA:
undetectable		 5nm5A-5vmtA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		5 / 10 ILE A 110
LEU A  83
VAL A  90
LEU A  88
GLU A  87
 None
 1.46A 5tixB-5vmtA:
undetectable		 5tixB-5vmtA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5vmt GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Neisseria
gonorrhoeae) 		5 / 12 SER A 210
ALA A 216
TYR A 313
ALA A 213
GLY A 212
 None
 1.17A 5tzoB-5vmtA:
undetectable		 5tzoB-5vmtA:
21.60