SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vn5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_A_NIOA704_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		4 / 4 SER A 239
PHE A 246
GLU A 236
GLY A 233
 None
 1.40A 1icvA-5vn5A:
undetectable
1icvB-5vn5A:
undetectable		 1icvA-5vn5A:
23.08
1icvB-5vn5A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_A_LPRA801_1
(ANGIOTENSIN
CONVERTING ENZYME)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		5 / 12 HIS A   8
THR A 181
GLU A 198
HIS A   6
VAL A 258
 ZN  A 400 (-3.2A)
None
None
ZN  A 400 (-3.3A)
None
 1.13A 1j36A-5vn5A:
undetectable		 1j36A-5vn5A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_B_LPRB802_1
(ANGIOTENSIN
CONVERTING ENZYME)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		5 / 12 HIS A   8
THR A 181
GLU A 198
HIS A   6
VAL A 258
 ZN  A 400 (-3.2A)
None
None
ZN  A 400 (-3.3A)
None
 1.13A 1j36B-5vn5A:
undetectable		 1j36B-5vn5A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PNL_B_PACB559_0
(PENICILLIN
AMIDOHYDROLASE)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		4 / 8 MET A 107
SER A  10
ALA A  45
ILE A  56
 None
 1.15A 1pnlA-5vn5A:
undetectable
1pnlB-5vn5A:
undetectable		 1pnlA-5vn5A:
18.84
1pnlB-5vn5A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVT_A_PRLA311_0
(TRANSCRIPTIONAL
REGULATOR QACR)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		4 / 8 LEU A 265
GLU A 262
THR A 294
ILE A 301
 None
 0.91A 1qvtA-5vn5A:
undetectable		 1qvtA-5vn5A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		4 / 7 PHE A 194
TYR A 190
VAL A 286
GLY A 285
 None
 0.98A 1t88A-5vn5A:
undetectable		 1t88A-5vn5A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		4 / 7 PHE A 194
TYR A 190
VAL A 286
GLY A 285
 None
 0.97A 2a1mA-5vn5A:
undetectable		 2a1mA-5vn5A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_A_097A1001_1
(ADAMTS-1)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		5 / 9 HIS A 223
GLU A 198
HIS A 179
HIS A   6
LEU A 259
 None
None
ZN  A 400 (-3.2A)
ZN  A 400 (-3.3A)
None
 1.27A 2jihA-5vn5A:
undetectable		 2jihA-5vn5A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_F_HAEF3004_1
(COLLAGENASE 3)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		3 / 3 HIS A   6
HIS A   8
HIS A 179
 ZN  A 400 (-3.3A)
ZN  A 400 (-3.2A)
ZN  A 400 (-3.2A)
 0.37A 2ozrF-5vn5A:
undetectable		 2ozrF-5vn5A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_F_HAEF3004_1
(COLLAGENASE 3)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		3 / 3 HIS A 223
HIS A   6
HIS A 179
 None
ZN  A 400 (-3.3A)
ZN  A 400 (-3.2A)
 0.50A 2ozrF-5vn5A:
undetectable		 2ozrF-5vn5A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_2
(PROTEASE)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		5 / 10 LEU A 142
ALA A 201
VAL A 221
ALA A 176
ILE A 178
 None
 0.94A 3ekpB-5vn5A:
undetectable		 3ekpB-5vn5A:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_B_097B801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		5 / 9 HIS A   6
HIS A 179
HIS A   8
ILE A  69
LEU A  68
 ZN  A 400 (-3.3A)
ZN  A 400 (-3.2A)
ZN  A 400 (-3.2A)
None
None
 1.28A 3hy7B-5vn5A:
undetectable		 3hy7B-5vn5A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		5 / 12 GLU A 198
ALA A 180
GLY A 182
SER A 183
ALA A 201
 None
 1.29A 3ou6C-5vn5A:
undetectable		 3ou6C-5vn5A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_D_ACTD504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		3 / 3 GLY A 287
SER A 288
TRP A  51
 None
 0.69A 4e7cD-5vn5A:
0.9		 4e7cD-5vn5A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		4 / 6 GLN A 100
PHE A 108
ILE A  97
PRO A 110
 None
 1.08A 4fgkA-5vn5A:
undetectable		 4fgkA-5vn5A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_A_SAMA301_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		5 / 12 GLY A 226
ALA A 201
HIS A 223
VAL A 221
VAL A 219
 None
 0.86A 4htfA-5vn5A:
undetectable		 4htfA-5vn5A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_B_SAMB301_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		5 / 12 GLY A 226
ALA A 201
HIS A 223
VAL A 221
VAL A 219
 None
 0.88A 4htfB-5vn5A:
undetectable		 4htfB-5vn5A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB301_1
(CHITOSANASE)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		3 / 3 GLY A 285
PRO A 284
GLN A 297
 None
 0.52A 4oltB-5vn5A:
undetectable		 4oltB-5vn5A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		5 / 12 LEU A 157
ASN A 204
GLY A 158
LEU A 217
ILE A 200
 None
 1.43A 4p6xA-5vn5A:
undetectable		 4p6xA-5vn5A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		5 / 12 LEU A 157
ASN A 204
GLY A 158
LEU A 217
ILE A 200
 None
 1.42A 4p6xE-5vn5A:
undetectable		 4p6xE-5vn5A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB305_1
(CHITOSANASE)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		3 / 3 GLY A 285
PRO A 284
GLN A 297
 None
 0.52A 4qwpB-5vn5A:
undetectable		 4qwpB-5vn5A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_C_QDNC602_1
(CYTOCHROME P450 2D6)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		5 / 11 LEU A  59
GLY A   7
GLN A  67
ALA A  45
SER A  10
 None
 1.23A 4wnuC-5vn5A:
undetectable		 4wnuC-5vn5A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA601_0
(LACCASE 2)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		4 / 4 HIS A   8
HIS A 223
HIS A 179
HIS A   6
 ZN  A 400 (-3.2A)
None
ZN  A 400 (-3.2A)
ZN  A 400 (-3.3A)
 0.99A 5mhwA-5vn5A:
undetectable		 5mhwA-5vn5A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA602_0
(LACCASE 2)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		4 / 5 HIS A 223
HIS A 179
HIS A   6
HIS A   8
 None
ZN  A 400 (-3.2A)
ZN  A 400 (-3.3A)
ZN  A 400 (-3.2A)
 1.03A 5mhwA-5vn5A:
undetectable		 5mhwA-5vn5A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA601_0
(LACCASE 2)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		4 / 4 HIS A   8
HIS A 223
HIS A 179
HIS A   6
 ZN  A 400 (-3.2A)
None
ZN  A 400 (-3.2A)
ZN  A 400 (-3.3A)
 0.99A 5mhxA-5vn5A:
undetectable		 5mhxA-5vn5A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA602_0
(LACCASE 2)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		4 / 5 HIS A 223
HIS A 179
HIS A   6
HIS A   8
 None
ZN  A 400 (-3.2A)
ZN  A 400 (-3.3A)
ZN  A 400 (-3.2A)
 1.03A 5mhxA-5vn5A:
undetectable		 5mhxA-5vn5A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA601_0
(LACCASE 2)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		4 / 4 HIS A   8
HIS A 223
HIS A 179
HIS A   6
 ZN  A 400 (-3.2A)
None
ZN  A 400 (-3.2A)
ZN  A 400 (-3.3A)
 0.99A 5mhyA-5vn5A:
undetectable		 5mhyA-5vn5A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA602_0
(LACCASE 2)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		4 / 5 HIS A 223
HIS A 179
HIS A   6
HIS A   8
 None
ZN  A 400 (-3.2A)
ZN  A 400 (-3.3A)
ZN  A 400 (-3.2A)
 1.03A 5mhyA-5vn5A:
undetectable		 5mhyA-5vn5A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA601_0
(LACCASE 2)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		4 / 4 HIS A   8
HIS A 223
HIS A 179
HIS A   6
 ZN  A 400 (-3.2A)
None
ZN  A 400 (-3.2A)
ZN  A 400 (-3.3A)
 1.00A 5mhzA-5vn5A:
undetectable		 5mhzA-5vn5A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA602_0
(LACCASE 2)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		4 / 5 HIS A 223
HIS A 179
HIS A   6
HIS A   8
 None
ZN  A 400 (-3.2A)
ZN  A 400 (-3.3A)
ZN  A 400 (-3.2A)
 1.03A 5mhzA-5vn5A:
undetectable		 5mhzA-5vn5A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA601_0
(LACCASE 2)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		4 / 4 HIS A   8
HIS A 223
HIS A 179
HIS A   6
 ZN  A 400 (-3.2A)
None
ZN  A 400 (-3.2A)
ZN  A 400 (-3.3A)
 1.00A 5mi1A-5vn5A:
undetectable		 5mi1A-5vn5A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA602_0
(LACCASE 2)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		4 / 5 HIS A 223
HIS A 179
HIS A   6
HIS A   8
 None
ZN  A 400 (-3.2A)
ZN  A 400 (-3.3A)
ZN  A 400 (-3.2A)
 1.03A 5mi1A-5vn5A:
undetectable		 5mi1A-5vn5A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA601_0
(LACCASE 2)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		4 / 4 HIS A   8
HIS A 223
HIS A 179
HIS A   6
 ZN  A 400 (-3.2A)
None
ZN  A 400 (-3.2A)
ZN  A 400 (-3.3A)
 1.00A 5mi2A-5vn5A:
undetectable		 5mi2A-5vn5A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA602_0
(LACCASE 2)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		4 / 5 HIS A 223
HIS A 179
HIS A   6
HIS A   8
 None
ZN  A 400 (-3.2A)
ZN  A 400 (-3.3A)
ZN  A 400 (-3.2A)
 1.03A 5mi2A-5vn5A:
undetectable		 5mi2A-5vn5A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA601_0
(LACCASE 2)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		4 / 4 HIS A   8
HIS A 223
HIS A 179
HIS A   6
 ZN  A 400 (-3.2A)
None
ZN  A 400 (-3.2A)
ZN  A 400 (-3.3A)
 1.01A 5miaA-5vn5A:
undetectable		 5miaA-5vn5A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA602_0
(LACCASE 2)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		4 / 5 HIS A 223
HIS A 179
HIS A   6
HIS A   8
 None
ZN  A 400 (-3.2A)
ZN  A 400 (-3.3A)
ZN  A 400 (-3.2A)
 1.03A 5miaA-5vn5A:
undetectable		 5miaA-5vn5A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA601_0
(LACCASE 2)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		4 / 4 HIS A   8
HIS A 223
HIS A 179
HIS A   6
 ZN  A 400 (-3.2A)
None
ZN  A 400 (-3.2A)
ZN  A 400 (-3.3A)
 1.01A 5mibA-5vn5A:
undetectable		 5mibA-5vn5A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA602_0
(LACCASE 2)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		4 / 5 HIS A 223
HIS A 179
HIS A   6
HIS A   8
 None
ZN  A 400 (-3.2A)
ZN  A 400 (-3.3A)
ZN  A 400 (-3.2A)
 1.03A 5mibA-5vn5A:
undetectable		 5mibA-5vn5A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA601_0
(LACCASE 2)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		4 / 4 HIS A   8
HIS A 223
HIS A 179
HIS A   6
 ZN  A 400 (-3.2A)
None
ZN  A 400 (-3.2A)
ZN  A 400 (-3.3A)
 1.01A 5micA-5vn5A:
undetectable		 5micA-5vn5A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA602_0
(LACCASE 2)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		4 / 5 HIS A 223
HIS A 179
HIS A   6
HIS A   8
 None
ZN  A 400 (-3.2A)
ZN  A 400 (-3.3A)
ZN  A 400 (-3.2A)
 1.03A 5micA-5vn5A:
undetectable		 5micA-5vn5A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		4 / 4 HIS A   8
HIS A 223
HIS A 179
HIS A   6
 ZN  A 400 (-3.2A)
None
ZN  A 400 (-3.2A)
ZN  A 400 (-3.3A)
 1.00A 5midA-5vn5A:
undetectable		 5midA-5vn5A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA602_0
(LACCASE 2)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		4 / 5 HIS A 223
HIS A 179
HIS A   6
HIS A   8
 None
ZN  A 400 (-3.2A)
ZN  A 400 (-3.3A)
ZN  A 400 (-3.2A)
 1.03A 5midA-5vn5A:
undetectable		 5midA-5vn5A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA601_0
(LACCASE 2)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		4 / 4 HIS A   8
HIS A 223
HIS A 179
HIS A   6
 ZN  A 400 (-3.2A)
None
ZN  A 400 (-3.2A)
ZN  A 400 (-3.3A)
 1.01A 5mieA-5vn5A:
undetectable		 5mieA-5vn5A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA602_0
(LACCASE 2)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		4 / 5 HIS A 223
HIS A 179
HIS A   6
HIS A   8
 None
ZN  A 400 (-3.2A)
ZN  A 400 (-3.3A)
ZN  A 400 (-3.2A)
 1.03A 5mieA-5vn5A:
undetectable		 5mieA-5vn5A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA602_0
(LACCASE 2)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		4 / 5 HIS A 223
HIS A 179
HIS A   6
HIS A   8
 None
ZN  A 400 (-3.2A)
ZN  A 400 (-3.3A)
ZN  A 400 (-3.2A)
 1.04A 5migA-5vn5A:
undetectable		 5migA-5vn5A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TQR_B_SAMB8009_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EZH2, POLYCOMB
PROTEIN SUZ12)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		5 / 10 LEU A  58
CYH A 283
GLY A 285
VAL A 258
HIS A 300
 None
 1.14A 5tqrB-5vn5A:
undetectable		 5tqrB-5vn5A:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		4 / 5 HIS A 179
HIS A   6
HIS A   8
PHE A 194
 ZN  A 400 (-3.2A)
ZN  A 400 (-3.3A)
ZN  A 400 (-3.2A)
None
 1.21A 5zrdB-5vn5A:
undetectable		 5zrdB-5vn5A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		4 / 5 HIS A 179
HIS A   6
HIS A   8
PHE A 194
 ZN  A 400 (-3.2A)
ZN  A 400 (-3.3A)
ZN  A 400 (-3.2A)
None
 1.25A 5zrdD-5vn5A:
undetectable		 5zrdD-5vn5A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_2
(-)		 5vn5 2,2',3-TRIHYDROXY-3'
-METHOXY-5,5'-DICARB
OXYBIPHENYL
META-CLEAVAGE
COMPOUND HYDROLASE
(Sphingobium
sp.
SYK-6) 		5 / 12 GLY A 226
GLY A 225
GLY A 182
HIS A   6
GLU A 148
 None
None
None
ZN  A 400 (-3.3A)
None
 1.00A 6gngB-5vn5A:
undetectable		 6gngB-5vn5A:
20.61