SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vn6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_D_CHDD702_0
(FERROCHELATASE)		 5vn6 TAURINE DIOXYGENASE
(Burkholderia
ambifaria) 		3 / 3 ARG A 270
GLY A 118
PRO A 119
 None
 0.63A 2hreD-5vn6A:
undetectable		 2hreD-5vn6A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LBD_A_REAA500_1
(RETINOIC ACID
RECEPTOR GAMMA)		 5vn6 TAURINE DIOXYGENASE
(Burkholderia
ambifaria) 		5 / 12 LEU A  36
ARG A  33
ILE A  32
PHE A  57
GLY A  11
 None
 1.28A 2lbdA-5vn6A:
undetectable		 2lbdA-5vn6A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5vn6 TAURINE DIOXYGENASE
(Burkholderia
ambifaria) 		4 / 5 ARG A 210
GLN A 143
LEU A 148
PHE A 202
 None
 1.39A 3ablC-5vn6A:
undetectable
3ablJ-5vn6A:
undetectable		 3ablC-5vn6A:
21.55
3ablJ-5vn6A:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5vn6 TAURINE DIOXYGENASE
(Burkholderia
ambifaria) 		5 / 12 ALA A 249
PHE A  43
LEU A   6
THR A 256
VAL A 239
 None
 1.08A 3rukA-5vn6A:
undetectable		 3rukA-5vn6A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_C_9PLC501_1
(CYTOCHROME P450 2E1)		 5vn6 TAURINE DIOXYGENASE
(Burkholderia
ambifaria) 		4 / 5 PHE A 202
ALA A 150
THR A 199
LEU A 193
 None
 1.06A 3t3zC-5vn6A:
undetectable		 3t3zC-5vn6A:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5vn6 TAURINE DIOXYGENASE
(Burkholderia
ambifaria) 		5 / 11 ALA A 274
GLY A 275
GLU A  65
GLY A  71
HIS A  76
 None
 1.07A 4e47A-5vn6A:
undetectable		 4e47A-5vn6A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_B_SAMB800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5vn6 TAURINE DIOXYGENASE
(Burkholderia
ambifaria) 		5 / 11 ALA A 274
GLY A 275
GLU A  65
GLY A  71
HIS A  76
 None
 1.07A 4e47B-5vn6A:
undetectable		 4e47B-5vn6A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_C_SAMC800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5vn6 TAURINE DIOXYGENASE
(Burkholderia
ambifaria) 		5 / 11 ALA A 274
GLY A 275
GLU A  65
GLY A  71
HIS A  76
 None
 1.00A 4e47C-5vn6A:
undetectable		 4e47C-5vn6A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5vn6 TAURINE DIOXYGENASE
(Burkholderia
ambifaria) 		5 / 11 ALA A 274
GLY A 275
GLU A  65
GLY A  71
HIS A  76
 None
 1.09A 4jdsA-5vn6A:
undetectable		 4jdsA-5vn6A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_B_SAMB401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5vn6 TAURINE DIOXYGENASE
(Burkholderia
ambifaria) 		5 / 11 ALA A 274
GLY A 275
GLU A  65
GLY A  71
HIS A  76
 None
 1.08A 4jdsB-5vn6A:
undetectable		 4jdsB-5vn6A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_C_SAMC401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5vn6 TAURINE DIOXYGENASE
(Burkholderia
ambifaria) 		5 / 11 ALA A 274
GLY A 275
GLU A  65
GLY A  71
HIS A  76
 None
 1.03A 4jdsC-5vn6A:
undetectable		 4jdsC-5vn6A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLG_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5vn6 TAURINE DIOXYGENASE
(Burkholderia
ambifaria) 		5 / 12 ALA A 274
GLY A 275
GLU A  65
GLY A  71
HIS A  76
 None
 1.10A 4jlgA-5vn6A:
undetectable		 4jlgA-5vn6A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_A_ASCA501_0
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 5vn6 TAURINE DIOXYGENASE
(Burkholderia
ambifaria) 		5 / 11 HIS A 258
GLN A 257
ASP A 100
ALA A 101
PHE A 198
 MG  A 300 (-3.3A)
None
MG  A 300 (-2.7A)
None
None
 1.32A 4rp8A-5vn6A:
0.0		 4rp8A-5vn6A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP9_A_ASCA501_0
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 5vn6 TAURINE DIOXYGENASE
(Burkholderia
ambifaria) 		5 / 12 HIS A 258
GLN A 257
ASP A 100
ALA A 101
PHE A 198
 MG  A 300 (-3.3A)
None
MG  A 300 (-2.7A)
None
None
 1.31A 4rp9A-5vn6A:
undetectable		 4rp9A-5vn6A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_2
(CYTOCHROME P450 2D6)		 5vn6 TAURINE DIOXYGENASE
(Burkholderia
ambifaria) 		3 / 3 GLU A 187
ILE A 250
ALA A 255
 None
 0.47A 4wnwB-5vn6A:
undetectable		 4wnwB-5vn6A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5vn6 TAURINE DIOXYGENASE
(Burkholderia
ambifaria) 		5 / 11 ALA A 274
GLY A 275
GLU A  65
GLY A  71
HIS A  76
 None
 1.00A 5ayfA-5vn6A:
undetectable		 5ayfA-5vn6A:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA303_1
(CHITOSANASE)		 5vn6 TAURINE DIOXYGENASE
(Burkholderia
ambifaria) 		4 / 5 ASP A 100
VAL A  80
GLY A 275
ALA A 274
 MG  A 300 (-2.7A)
None
None
None
 0.99A 5hwaA-5vn6A:
undetectable		 5hwaA-5vn6A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 5vn6 TAURINE DIOXYGENASE
(Burkholderia
ambifaria) 		3 / 3 ALA A 133
ASN A 136
LEU A 137
 None
 0.34A 5i1oC-5vn6A:
undetectable		 5i1oC-5vn6A:
8.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 5vn6 TAURINE DIOXYGENASE
(Burkholderia
ambifaria) 		3 / 3 ALA A 133
ASN A 136
LEU A 137
 None
 0.36A 5i1pA-5vn6A:
undetectable		 5i1pA-5vn6A:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_A_Z80A401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 5vn6 TAURINE DIOXYGENASE
(Burkholderia
ambifaria) 		5 / 11 PHE A  43
ASP A 252
TRP A 127
ILE A 250
ALA A 249
 None
 1.02A 5lg3A-5vn6A:
undetectable		 5lg3A-5vn6A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_I_Z80I401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 5vn6 TAURINE DIOXYGENASE
(Burkholderia
ambifaria) 		4 / 9 PHE A  43
ASP A 252
TRP A 127
ILE A 250
 None
 1.01A 5lg3I-5vn6A:
undetectable		 5lg3I-5vn6A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA310_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5vn6 TAURINE DIOXYGENASE
(Burkholderia
ambifaria) 		3 / 3 GLU A 190
HIS A 185
ARG A 183
 None
 0.95A 5uunA-5vn6A:
undetectable		 5uunA-5vn6A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_2
(CYTOCHROME P450 3A4)		 5vn6 TAURINE DIOXYGENASE
(Burkholderia
ambifaria) 		3 / 3 ARG A 114
ARG A  81
ARG A 269
 None
 0.83A 5vcgA-5vn6A:
undetectable		 5vcgA-5vn6A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA411_0
(UNCHARACTERIZED
PROTEIN KDOO)		 5vn6 TAURINE DIOXYGENASE
(Burkholderia
ambifaria) 		3 / 3 LYS A 171
LEU A 168
ARG A 167
 None
 0.92A 5yw0A-5vn6A:
9.7		 5yw0A-5vn6A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8F_A_ACTA803_0
(UNCHARACTERIZED
PROTEIN)		 5vn6 TAURINE DIOXYGENASE
(Burkholderia
ambifaria) 		3 / 3 GLU A 135
LEU A 132
ARG A  40
 None
 0.40A 6d8fA-5vn6A:
undetectable		 6d8fA-5vn6A:
18.48