SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vnc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CD2_A_FOLA307_0
(DIHYDROFOLATE
REDUCTASE)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		6 / 12 ILE A  46
LEU A   9
PHE A 150
PRO A  75
LEU A  80
ILE A 104
 None
 1.37A 1cd2A-5vncA:
undetectable		 1cd2A-5vncA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		3 / 3 GLU A  12
HIS A 166
HIS A 168
 None
 0.65A 1oe2A-5vncA:
undetectable		 1oe2A-5vncA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_2
(RETINOIC ACID
RECEPTOR, BETA)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 176
PHE A 190
ARG A 230
 None
 0.50A 1xdkF-5vncA:
undetectable		 1xdkF-5vncA:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_1
(ANDROGEN RECEPTOR)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		5 / 12 VAL A 523
MET A 521
THR A 527
MET A 537
ILE A 553
 None
 1.27A 1z95A-5vncA:
undetectable		 1z95A-5vncA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_B_P1ZB2001_1
(SERUM ALBUMIN)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		5 / 9 TYR A  39
LEU A 614
HIS A   8
ARG A 610
ALA A 609
 None
 1.16A 2bxcB-5vncA:
undetectable		 2bxcB-5vncA:
7.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		5 / 12 GLU A 221
VAL A 216
LEU A 258
ARG A 224
PHE A 225
 None
 1.25A 2jj8C-5vncA:
undetectable		 2jj8C-5vncA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO0_B_GEOB302_1
(DEOXYCYTIDINE KINASE)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		5 / 12 VAL A  17
TRP A  95
LEU A  45
TYR A  43
GLU A  12
 None
 1.43A 2no0B-5vncA:
undetectable		 2no0B-5vncA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_B_CHDB504_0
(FERROCHELATASE)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		4 / 6 MET A 635
ILE A 189
ARG A 610
MET A 602
 None
 1.32A 2qd3B-5vncA:
2.7		 2qd3B-5vncA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1499_1
(CYTOCHROME P450 3A4)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		4 / 7 PHE A 209
LEU A 259
PHE A 190
ILE A 233
 None
 0.97A 2v0mC-5vncA:
undetectable		 2v0mC-5vncA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIA_B_CL9B401_1
(DEOXYCYTIDINE KINASE)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		5 / 12 VAL A  17
TRP A  95
LEU A  45
TYR A  43
GLU A  12
 None
 1.47A 2ziaB-5vncA:
1.7		 2ziaB-5vncA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA602_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		4 / 7 ALA A 238
ALA A 237
ALA A 241
GLN A 169
 None
 0.72A 3a2qA-5vncA:
undetectable		 3a2qA-5vncA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		4 / 7 HIS A 168
THR A  35
TYR A  39
HIS A 193
 None
 1.39A 3ag2A-5vncA:
undetectable
3ag2C-5vncA:
undetectable		 3ag2A-5vncA:
undetectable
3ag2C-5vncA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		4 / 7 LEU A  80
GLN A  81
PHE A  90
PHE A  11
 None
 1.01A 3ag2C-5vncA:
undetectable		 3ag2C-5vncA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA1_0
(FERROCHELATASE)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		5 / 11 LEU A 335
PHE A 331
MET A 474
ILE A 526
VAL A 297
 None
 1.46A 3aqiA-5vncA:
3.4		 3aqiA-5vncA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_2
(ADENOSYLHOMOCYSTEINA
SE)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		3 / 3 THR A 246
GLU A 254
HIS A 257
 None
 0.77A 3g1uB-5vncA:
4.4		 3g1uB-5vncA:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IIZ_A_SAMA1501_0
(BIOTIN SYNTHETASE,
PUTATIVE)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		5 / 12 SER A 124
GLY A 127
ILE A 184
TYR A 145
LEU A 178
 None
 1.11A 3iizA-5vncA:
2.2		 3iizA-5vncA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECNB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		5 / 9 THR A  35
TYR A  39
GLY A 603
THR A 245
ILE A 189
 None
 1.22A 3jusB-5vncA:
undetectable		 3jusB-5vncA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_B_KKKB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		5 / 12 PHE A 150
TYR A  39
GLY A 603
THR A 245
ILE A 189
 None
 1.22A 3ld6B-5vncA:
undetectable		 3ld6B-5vncA:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4APJ_A_ACTA1635_0
(ANGIOTENSIN-CONVERTI
NG ENZYME
BRADYKININ-POTENTIAT
ING PEPTIDE B)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		4 / 6 HIS A  42
HIS A  44
ASP A  41
SER A  70
 None
 1.33A 4apjA-5vncA:
3.1
4apjP-5vncA:
undetectable		 4apjA-5vncA:
undetectable
4apjP-5vncA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4APJ_A_ACTA1635_0
(ANGIOTENSIN-CONVERTI
NG ENZYME
BRADYKININ-POTENTIAT
ING PEPTIDE B)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		4 / 6 HIS A 161
GLU A  72
ASP A  41
SER A  70
 None
 0.98A 4apjA-5vncA:
3.1
4apjP-5vncA:
undetectable		 4apjA-5vncA:
undetectable
4apjP-5vncA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_D_NCTD501_1
(CYTOCHROME P450 2A13)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		4 / 6 PHE A 209
ALA A 194
THR A 192
LEU A 259
 None
 0.95A 4ejgD-5vncA:
undetectable		 4ejgD-5vncA:
9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_D_D16D301_1
(THYMIDYLATE SYNTHASE)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 475
PHE A 296
TYR A 492
VAL A 356
ALA A 318
 None
None
UDP  A 801 (-3.2A)
None
UDP  A 801 ( 4.3A)
 1.14A 4foxD-5vncA:
undetectable		 4foxD-5vncA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FQS_A_LYAA302_1
(THYMIDYLATE SYNTHASE)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 475
PHE A 296
TYR A 492
VAL A 356
ALA A 318
 None
None
UDP  A 801 (-3.2A)
None
UDP  A 801 ( 4.3A)
 1.14A 4fqsA-5vncA:
undetectable		 4fqsA-5vncA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FQS_B_LYAB302_1
(THYMIDYLATE SYNTHASE)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 475
PHE A 296
TYR A 492
VAL A 356
ALA A 318
 None
None
UDP  A 801 (-3.2A)
None
UDP  A 801 ( 4.3A)
 1.15A 4fqsB-5vncA:
undetectable		 4fqsB-5vncA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JXC_A_SAMA402_0
(FEFE-HYDROGENASE
MATURASE)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		5 / 12 SER A 124
GLY A 127
ILE A 184
TYR A 145
LEU A 178
 None
 1.12A 4jxcA-5vncA:
2.0		 4jxcA-5vncA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_MTLA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 261
ASP A 264
ASP A 632
ARG A 616
 None
 1.40A 4kcnA-5vncA:
undetectable		 4kcnA-5vncA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1A_A_AB1A101_1
(MDR769 HIV-1
PROTEASE)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		5 / 11 GLY A 152
ALA A 155
ILE A 104
THR A 188
VAL A 186
 None
 1.13A 4l1aA-5vncA:
undetectable		 4l1aA-5vncA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_A_BQ1A1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		3 / 3 GLU A 221
ALA A 222
PHE A 225
 None
 0.32A 4v1fA-5vncA:
4.8		 4v1fA-5vncA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_C_BQ1C1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		3 / 3 GLU A 221
ALA A 222
PHE A 225
 None
 0.35A 4v1fC-5vncA:
4.4		 4v1fC-5vncA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FXT_A_0LAA1376_1
(DNA POLYMERASE III
SUBUNIT BETA)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		4 / 7 LEU A 568
PRO A 505
ILE A 317
MET A 474
 None
 1.06A 5fxtA-5vncA:
undetectable		 5fxtA-5vncA:
11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA303_1
(CHITOSANASE)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		4 / 5 HIS A 166
VAL A 147
GLY A 173
ALA A 175
 None
 0.99A 5hwaA-5vncA:
undetectable		 5hwaA-5vncA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGP_A_ERYA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		4 / 4 ASP A 208
TYR A 507
MET A 330
PHE A 558
 None
 1.39A 5igpA-5vncA:
0.1		 5igpA-5vncA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_C_CVIC301_1
(REGULATORY PROTEIN
TETR)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		4 / 7 GLY A 173
ILE A 128
TRP A 170
TYR A 145
 None
 1.08A 5vlmC-5vncA:
undetectable		 5vlmC-5vncA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA816_0
(UNCHARACTERIZED
PROTEIN)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 616
ARG A 615
ASP A 632
 None
 0.98A 6d8pA-5vncA:
undetectable		 6d8pA-5vncA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DHB_A_BEZA202_0
(HEPATITIS A VIRUS
CELLULAR RECEPTOR 2)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		4 / 6 ILE A 442
MET A 474
ASN A 466
ASP A 470
 None
 1.40A 6dhbA-5vncA:
undetectable		 6dhbA-5vncA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FI4_B_DVAB8_0
(14-3-3 PROTEIN SIGMA
PRO-SEP-LEU-PRO-DVA)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		4 / 5 SER A 531
VAL A 530
ASN A 529
PRO A 505
 None
 1.31A 6fi4A-5vncA:
3.2
6fi4B-5vncA:
undetectable		 6fi4A-5vncA:
undetectable
6fi4B-5vncA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_A_ACRA602_1
(-)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		6 / 12 GLY A  22
GLY A  23
VAL A  27
VAL A 247
ASN A 269
PRO A 510
 None
 0.72A 6gneA-5vncA:
22.7		 6gneA-5vncA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_A_ACRA602_1
(-)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		6 / 12 GLY A  23
VAL A  27
VAL A 247
ASN A 269
PRO A 510
GLY A 512
 None
None
None
None
None
UDP  A 801 (-3.5A)
 0.77A 6gneA-5vncA:
22.7		 6gneA-5vncA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_1
(-)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		7 / 12 GLU A  16
GLY A  22
GLY A  23
VAL A  27
VAL A 247
ASN A 269
PRO A 510
 None
 0.85A 6gneB-5vncA:
22.6		 6gneB-5vncA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_1
(-)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		7 / 12 GLU A  16
GLY A  23
VAL A  27
VAL A 247
ASN A 269
PRO A 510
GLY A 512
 None
None
None
None
None
None
UDP  A 801 (-3.5A)
 0.89A 6gneB-5vncA:
22.6		 6gneB-5vncA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_A_QPSA602_1
(-)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		5 / 12 VAL A  27
ASN A 269
GLU A 509
PRO A 510
GLY A 512
 None
None
UDP  A 801 (-3.9A)
None
UDP  A 801 (-3.5A)
 0.86A 6gnfA-5vncA:
10.1		 6gnfA-5vncA:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_A_QPSA602_2
(-)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		5 / 9 GLY A  22
GLY A  23
TRP A 170
HIS A 193
VAL A 247
 None
 0.84A 6gnfA-5vncA:
10.1		 6gnfA-5vncA:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_A_QPSA602_2
(-)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		5 / 9 GLY A  22
TRP A 170
HIS A 193
VAL A 247
GLU A 322
 None
 1.43A 6gnfA-5vncA:
10.1		 6gnfA-5vncA:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_C_QPSC602_2
(-)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		5 / 12 VAL A  27
ASN A 269
GLU A 509
PRO A 510
GLY A 512
 None
None
UDP  A 801 (-3.9A)
None
UDP  A 801 (-3.5A)
 0.87A 6gnfC-5vncA:
21.0		 6gnfC-5vncA:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		7 / 12 GLU A  16
GLY A  23
TRP A 170
HIS A 193
VAL A 247
PRO A 510
GLY A 512
 None
None
None
None
None
None
UDP  A 801 (-3.5A)
 0.88A 6gngA-5vncA:
21.1		 6gngA-5vncA:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		5 / 12 HIS A 193
VAL A 247
GLU A 509
PRO A 510
GLY A 512
 None
None
UDP  A 801 (-3.9A)
None
UDP  A 801 (-3.5A)
 0.94A 6gngA-5vncA:
21.1		 6gngA-5vncA:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_1
(-)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		5 / 12 VAL A  27
HIS A 193
VAL A 247
GLU A 509
GLY A 512
 None
None
None
UDP  A 801 (-3.9A)
UDP  A 801 (-3.5A)
 1.01A 6gngB-5vncA:
10.1		 6gngB-5vncA:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_1
(-)		 5vnc GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2
(Saccharomyces
cerevisiae) 		5 / 12 VAL A  27
TRP A 170
HIS A 193
VAL A 247
GLY A 512
 None
None
None
None
UDP  A 801 (-3.5A)
 0.72A 6gngB-5vncA:
10.1		 6gngB-5vncA:
10.13