SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vo5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_A_KANA558_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 5vo5 COILED-COIL AND C2
DOMAIN-CONTAINING
PROTEIN
1-LIKE,GH13992P
(Drosophila
melanogaster) 		4 / 7 ASP A 139
GLU A 146
GLU A 150
GLU A  25
 None
 1.07A 1knyA-5vo5A:
2.3
1knyB-5vo5A:
3.6		 1knyA-5vo5A:
21.03
1knyB-5vo5A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_B_KANB559_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 5vo5 COILED-COIL AND C2
DOMAIN-CONTAINING
PROTEIN
1-LIKE,GH13992P
(Drosophila
melanogaster) 		4 / 8 GLU A  25
ASP A 139
GLU A 146
GLU A 150
 None
 1.14A 1knyA-5vo5A:
2.3
1knyB-5vo5A:
3.6		 1knyA-5vo5A:
21.03
1knyB-5vo5A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_B_RBFB202_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 5vo5 COILED-COIL AND C2
DOMAIN-CONTAINING
PROTEIN
1-LIKE,GH13992P
(Drosophila
melanogaster) 		5 / 11 PRO A  60
GLU A 146
VAL A  38
TYR A  15
GLU A 150
 None
 1.41A 2fl5A-5vo5A:
undetectable
2fl5B-5vo5A:
undetectable
2fl5F-5vo5A:
undetectable		 2fl5A-5vo5A:
18.06
2fl5B-5vo5A:
19.23
2fl5F-5vo5A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)		 5vo5 COILED-COIL AND C2
DOMAIN-CONTAINING
PROTEIN
1-LIKE,GH13992P
(Drosophila
melanogaster) 		4 / 7 LEU A   8
TYR A  48
MET A   4
LEU A  59
 None
 1.05A 5jq7B-5vo5A:
undetectable		 5jq7B-5vo5A:
22.55