SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vob'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5vob ENVELOPE
GLYCOPROTEIN UL128
(Human
betaherpesvirus
5) 		4 / 7 ILE C 109
LEU C 103
THR C  85
LEU C  84
 None
 0.89A 1v54N-5vobC:
undetectable
1v54W-5vobC:
undetectable		 1v54N-5vobC:
14.92
1v54W-5vobC:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5vob ENVELOPE
GLYCOPROTEIN UL128
(Human
betaherpesvirus
5) 		4 / 7 ILE C 109
LEU C 103
THR C  85
LEU C  84
 None
 0.90A 2dyrN-5vobC:
undetectable
2dyrW-5vobC:
undetectable		 2dyrN-5vobC:
14.92
2dyrW-5vobC:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5vob ENVELOPE
GLYCOPROTEIN UL128
(Human
betaherpesvirus
5) 		4 / 8 ILE C 109
LEU C 103
THR C  85
LEU C  84
 None
 0.84A 2eijN-5vobC:
undetectable
2eijW-5vobC:
undetectable		 2eijN-5vobC:
14.92
2eijW-5vobC:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5vob ENVELOPE
GLYCOPROTEIN UL128
(Human
betaherpesvirus
5) 		4 / 8 ILE C 109
LEU C 103
THR C  85
LEU C  84
 None
 0.88A 2eikN-5vobC:
undetectable
2eikW-5vobC:
undetectable		 2eikN-5vobC:
14.92
2eikW-5vobC:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5vob ENVELOPE
GLYCOPROTEIN UL128
(Human
betaherpesvirus
5) 		4 / 8 ILE C 109
LEU C 103
THR C  85
LEU C  84
 None
 0.83A 2eilN-5vobC:
undetectable
2eilW-5vobC:
undetectable		 2eilN-5vobC:
14.92
2eilW-5vobC:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5vob ENVELOPE
GLYCOPROTEIN UL128
(Human
betaherpesvirus
5) 		4 / 7 ILE C 109
LEU C 103
THR C  85
LEU C  84
 None
 0.91A 3ablA-5vobC:
undetectable
3ablJ-5vobC:
undetectable		 3ablA-5vobC:
14.92
3ablJ-5vobC:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5vob ENVELOPE
GLYCOPROTEIN UL128
(Human
betaherpesvirus
5) 		4 / 8 ILE C 109
LEU C 103
THR C  85
LEU C  84
 None
 0.81A 3ablN-5vobC:
undetectable
3ablW-5vobC:
undetectable		 3ablN-5vobC:
14.92
3ablW-5vobC:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5vob ENVELOPE
GLYCOPROTEIN UL128
(Human
betaherpesvirus
5) 		4 / 8 ILE C 109
LEU C 103
THR C  85
LEU C  84
 None
 0.85A 3ag3N-5vobC:
undetectable
3ag3W-5vobC:
undetectable		 3ag3N-5vobC:
14.92
3ag3W-5vobC:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5vob ENVELOPE
GLYCOPROTEIN UL128
(Human
betaherpesvirus
5) 		4 / 8 ILE C 109
LEU C 103
THR C  85
LEU C  84
 None
 0.85A 3asnN-5vobC:
undetectable
3asnW-5vobC:
undetectable		 3asnN-5vobC:
14.92
3asnW-5vobC:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP1_A_ACTA590_0
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 5vob FAB 8I21 HEAVY CHAIN
(Homo
sapiens) 		4 / 5 GLU H   3
LEU H   4
GLN H 114
GLY H 113
 None
 1.17A 3pp1A-5vobH:
undetectable		 3pp1A-5vobH:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA501_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 5vob FAB 8I21 HEAVY CHAIN
(Homo
sapiens) 		4 / 5 TYR H  94
LEU H  81
LEU H  86
ARG H  67
 None
 1.22A 4em2A-5vobH:
undetectable		 4em2A-5vobH:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5vob ENVELOPE
GLYCOPROTEIN UL128
(Human
betaherpesvirus
5) 		4 / 7 ILE C 109
LEU C 103
THR C  85
LEU C  84
 None
 0.86A 5b1bA-5vobC:
undetectable
5b1bJ-5vobC:
undetectable		 5b1bA-5vobC:
14.92
5b1bJ-5vobC:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_C_ACTC403_0
(D-ALANINE--D-ALANINE
LIGASE)		 5vob FAB 8I21 HEAVY CHAIN
(Homo
sapiens) 		4 / 4 TYR H 203
GLY H 143
SER H 196
LEU H 198
 None
 1.25A 5bphC-5vobH:
undetectable		 5bphC-5vobH:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_D_ACTD403_0
(D-ALANINE--D-ALANINE
LIGASE)		 5vob FAB 8I21 HEAVY CHAIN
(Homo
sapiens) 		4 / 6 TYR H 203
GLY H 143
SER H 196
LEU H 198
 None
 1.25A 5bphD-5vobH:
undetectable		 5bphD-5vobH:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5vob ENVELOPE
GLYCOPROTEIN UL128
(Human
betaherpesvirus
5) 		4 / 7 ILE C 109
LEU C 103
THR C  85
LEU C  84
 None
 0.90A 5iy5A-5vobC:
undetectable
5iy5J-5vobC:
undetectable		 5iy5A-5vobC:
14.92
5iy5J-5vobC:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5vob ENVELOPE
GLYCOPROTEIN UL128
(Human
betaherpesvirus
5) 		4 / 7 ILE C 109
LEU C 103
THR C  85
LEU C  84
 None
 0.84A 5xdqA-5vobC:
undetectable
5xdqJ-5vobC:
undetectable		 5xdqA-5vobC:
14.92
5xdqJ-5vobC:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 5vob ENVELOPE
GLYCOPROTEIN UL128
(Human
betaherpesvirus
5) 		4 / 8 ILE C 109
LEU C 103
THR C  85
LEU C  84
 None
 0.86A 5xdxN-5vobC:
undetectable
5xdxW-5vobC:
undetectable		 5xdxN-5vobC:
14.92
5xdxW-5vobC:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5vob ENVELOPE
GLYCOPROTEIN UL128
(Human
betaherpesvirus
5) 		4 / 8 ILE C 109
LEU C 103
THR C  85
LEU C  84
 None
 0.87A 5zcoA-5vobC:
undetectable
5zcoJ-5vobC:
undetectable		 5zcoA-5vobC:
14.92
5zcoJ-5vobC:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5vob ENVELOPE
GLYCOPROTEIN UL128
(Human
betaherpesvirus
5) 		4 / 8 ILE C 109
LEU C 103
THR C  85
LEU C  84
 None
 0.84A 5zcqN-5vobC:
undetectable
5zcqW-5vobC:
undetectable		 5zcqN-5vobC:
14.92
5zcqW-5vobC:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA606_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 5vob FAB 8I21 HEAVY CHAIN
(Homo
sapiens) 		4 / 5 GLU H 157
PHE H 155
HIS H 209
THR H 119
 None
 1.15A 6b58A-5vobH:
undetectable		 6b58A-5vobH:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5vob ENVELOPE
GLYCOPROTEIN UL128
(Human
betaherpesvirus
5) 		4 / 7 ILE C 109
LEU C 103
THR C  85
LEU C  84
 None
 0.91A 6nmfA-5vobC:
undetectable
6nmfJ-5vobC:
undetectable		 6nmfA-5vobC:
14.92
6nmfJ-5vobC:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5vob ENVELOPE
GLYCOPROTEIN UL128
(Human
betaherpesvirus
5) 		4 / 7 ILE C 109
LEU C 103
THR C  85
LEU C  84
 None
 0.91A 6nmpA-5vobC:
undetectable
6nmpJ-5vobC:
undetectable		 6nmpA-5vobC:
14.92
6nmpJ-5vobC:
19.75