SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vod'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IB2_A_IBPA3960_1 (LACTOTRANSFERRIN)	5vod	FAB 9I6 HEAVY CHAIN (Homo sapiens)	4 / 4	GLY H 45 VAL H 21 GLY H 118 THR H 119	None	0.93A	3ib2A-5vodH: undetectable	3ib2A-5vodH: 22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C9P_A_CAMA423_0 (CYTOCHROME P450)	5vod	FAB 9I6 HEAVY CHAIN (Homo sapiens)	5 / 9	THR H 192 LEU H 151 GLY H 166 VAL H 225 VAL H 179	None	1.39A	4c9pA-5vodH: undetectable	4c9pA-5vodH: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JX1_B_CAMB502_0 (CAMPHOR 5-MONOOXYGENASE)	5vod	FAB 9I6 HEAVY CHAIN (Homo sapiens)	5 / 10	PHE H 149 GLY H 145 THR H 232 VAL H 225 VAL H 234	None	1.08A	4jx1B-5vodH: undetectable	4jx1B-5vodH: 20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P66_A_MTXA201_1 (DIHYDROFOLATE REDUCTASE)	5vod	FAB 9I6 HEAVY CHAIN (Homo sapiens)	5 / 11	ALA H 50 ASP H 46 LEU H 23 ILE H 53 TYR H 71	None	1.13A	4p66A-5vodH: undetectable	4p66A-5vodH: 19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E4D_B_BEZB202_0 (HYDROXYNITRILE LYASE)	5vod	FAB 9I6 HEAVY CHAIN (Homo sapiens)	4 / 7	VAL H 136 LEU H 105 MET H 67 VAL H 87	None	1.02A	5e4dA-5vodH: undetectable 5e4dB-5vodH: undetectable	5e4dA-5vodH: 20.89 5e4dB-5vodH: 20.89

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3IB2_A_IBPA3960_1","LACTOTRANSFERRIN","5vod","FAB 9I6 HEAVY CHAIN","Homo sapiens",4,"GLY H  45;VAL H  21;GLY H 118;THR H 119","None","0.93A","3ib2A-5vodH:undetectable","3ib2A-5vodH:22.74"],["4C9P_A_CAMA423_0","CYTOCHROME P450","5vod","FAB 9I6 HEAVY CHAIN","Homo sapiens",5,"THR H 192;LEU H 151;GLY H 166;VAL H 225;VAL H 179","None","1.39A","4c9pA-5vodH:undetectable","4c9pA-5vodH:22.45"],["4JX1_B_CAMB502_0","CAMPHOR 5-MONOOXYGENASE","5vod","FAB 9I6 HEAVY CHAIN","Homo sapiens",5,"PHE H 149;GLY H 145;THR H 232;VAL H 225;VAL H 234","None","1.08A","4jx1B-5vodH:undetectable","4jx1B-5vodH:20.76"],["4P66_A_MTXA201_1","DIHYDROFOLATE REDUCTASE","5vod","FAB 9I6 HEAVY CHAIN","Homo sapiens",5,"ALA H  50;ASP H  46;LEU H  23;ILE H  53;TYR H  71","None","1.13A","4p66A-5vodH:undetectable","4p66A-5vodH:19.44"],["5E4D_B_BEZB202_0","HYDROXYNITRILE LYASE","5vod","FAB 9I6 HEAVY CHAIN","Homo sapiens",4,"VAL H 136;LEU H 105;MET H  67;VAL H  87","None","1.02A","5e4dA-5vodH:undetectable;5e4dB-5vodH:undetectable","5e4dA-5vodH:20.89;5e4dB-5vodH:20.89"]]