SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5vog'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_C_BEZC264_0
(CARNITINYL-COA
DEHYDRATASE)		 5vog PUTATIVE
PHOSPHORIBOSYLTRANSF
ERASE
(Neisseria
gonorrhoeae) 		4 / 6 ALA A 124
ILE A  23
LEU A  94
ALA A  44
 None
 0.90A 3r9sC-5vogA:
undetectable		 3r9sC-5vogA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_A_SAMA401_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 5vog PUTATIVE
PHOSPHORIBOSYLTRANSF
ERASE
(Neisseria
gonorrhoeae) 		5 / 12 GLY A  37
VAL A  99
GLY A  39
GLY A  40
PRO A  43
 None
G4P  A 203 (-4.9A)
G4P  A 203 (-3.5A)
None
None
 1.11A 5wyqA-5vogA:
undetectable		 5wyqA-5vogA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 5vog PUTATIVE
PHOSPHORIBOSYLTRANSF
ERASE
(Neisseria
gonorrhoeae) 		4 / 8 ILE A  34
THR A 105
VAL A 104
GLU A 107
 None
EDO  A 202 ( 3.4A)
G4P  A 203 (-4.6A)
None
 1.06A 6fbvC-5vogA:
undetectable		 6fbvC-5vogA:
9.46